Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Rogue right-wing governor is repeatedly engaging in human trafficking. He’s violating the law, abusing state funds and state power, and deceiving helpless migrants. Why isn’t this a bigger story? https://www.theguardian.com/us-news/2023/jun/06/texas-migrants-flight-marthas-vineyard-charges-sheriff
Thiago Carvalho
boosted
🏳️🌈🖖🏽
A federal judge has ruled Florida’s ban on gender-affirming care for minors is likely unconstitutional and has issued an injunction halting enforcement of the ban.
Happy Pride, and thank you, federal judiciary!
Thiago Carvalho
boosted
Craig White & Dustin Marshall discuss in their JEB100 Commentary how they have developed a new theory to explain the evolutionary origin of metabolic scaling, presenting an overview of the approach and its limitations
#science #biology #zoology #comparativephysiology
https://journals.biologists.com/jeb/article/226/11/jeb245426/310832
File this one under "big if true":
"For decades, it was typical to use pelvic radiation. But the radiation puts women into immediate menopause and damages sexual function in men and women. It also can injure the bowel, causing issues like chronic diarrhea. Patients risk pelvic fractures, and the radiation can cause additional cancers.
Yet radiation treatment, the study found, did not improve outcomes."
Let's hope they lose big.
'The pharmaceutical company Merck on Tuesday sued the government over a federal law that empowers Medicare for the first time to negotiate prices directly with drugmakers.'
https://www.nytimes.com/2023/06/06/business/merck-medicare-drug-prices.html
Thiago Carvalho
boosted
This #TechnicalTuesday we are highlighting zFACE, a tool to quantitatively assess craniofacial development in #zebrafish from Lorena Maili, George Eisenhoffer and colleagues.
Read the full #OpenAccess article in @DMM_Journal https://journals.biologists.com/dmm/article/16/6/dmm049868/313484/Facial-analytics-based-on-a-coordinate
First person interview: https://journals.biologists.com/dmm/article/16/6/dmm050302/313489/First-person-Lorena-Maili
Thiago Carvalho
boosted
#SARSCoV2 ‘overlapping genes’ are often ignored, partly because they are difficult to annotate.
For example, ‘genes’ overlapping ORF3a (3b, 3c, 3d) and N (9b, 9c) may be of great importance—but are not annotated in the NCBI reference genome, Wuhan-Hu-1. elifesciences.org/articles/59633
"Presently, most nanobodies are produced by immunizing camelids; however, platforms for animal-free production are growing in popularity. Here, we describe the development of a fully synthetic nanobody library based on an engineered human VH3-23 variable gene and a multispecific antibody-like format designed for biparatopic target engagement."
Thiago Carvalho
boosted
Not “Everyone” Has Been Infected with COVID https://mikethemadbiologist.com/2023/06/06/not-everyone-has-been-infected-with-covid/
Thiago Carvalho
boosted
Ion Mobility Mass Spectrometry Unveils Global Protein Conformations in Response to Conditions that Promote and Reverse Liquid–Liquid Phase Separation | https://pubs.acs.org/doi/10.1021/jacs.3c00756 #proteomics
Thiago Carvalho
boosted
A fiber-free (FF) #MaternalDiet alters #microbiome establishment in pups, with diminished pre-weaning levels of Akkermansia muciniphila (AM). These results underscore the important influence of #MaternalDiet and #microbiome on immune maturation in offspring during a critical developmental period.
By E. Grant, M. Desai & colleagues
Thiago Carvalho
boosted
"Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences"
It takes researchers who do postdocs "about 15 years to catch up in salary to those who hadn’t, and that they earned between $128,000 and $240,000 less in total pay during this period."
via https://www.statnews.com/2023/06/06/postdoc-system-teetering-imperiling-life-sciences-diversity/
h/t @dmacphee
Thiago Carvalho
boosted
A falta de informação é o novo "não me recordo." É a desculpa para continuar a carregar sobre os salários quando a própria análise do BCE mostra que os lucros são o que tem aumentado verdadeiramente.
RT @IsabellaMWeber: BREAKING: Sellers' inflation is now a Christine Lagarde take.
https://t.co/UQ5rzSmU1U
🐦🔗: https://n.respublicae.eu/joseggusmao/status/1666069275541647360
Thiago Carvalho
boosted
Hepatic necroptosis and #HCC were caused by recombinant #AAV injection in hyperglycemic and obese mice, which could be alleviated by #prednisone administration or Pebp1/Tbk1 signaling inhibition.
By Y. Cheng, Z. Zhang, Q. Zhai & colleagues at University of Chinese Academy of Sciences
Thiago Carvalho
boosted
Gene therapy with AAV vectored micro-dystrophin for Duchenne muscular dystrophy. My latest #ClinicalPipeline column for #NatureMedicine.
'When Professor Harald zur Hausen, who has died aged 87, identified a link between the human papillomavirus and cervical cancer almost half a century ago, few of his fellow scientists took the breakthrough seriously.'
https://www.ft.com/content/eeb66a36-29e4-4a14-b7a4-0ca59214ad05
Thiago Carvalho
boosted
I just love Albrecht Dürer to pieces. You can practically hear the wind blowing over the grasses.
"The Great Piece of Turf"
Watercolor, pen and ink
1503
The intersection of macroeconomics and air mattresses
Early morning stats
"The purpose of this Viewpoint is to provide guidance on statistical analysis options for repeated measurements within the context of basic science. Analysis guidance is given considering various assumptions and repeated measures data structures."
Thiago Carvalho
boosted
New article! Read Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response https://www.nature.com/articles/s41541-023-00683-1?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
