#IDMastodon lung remodeling disease due to #COVID19. Respiratory viruses, including severe, acute #SarsCoV2 infection can trigger chronic lung disease that persists and even progresses after expected clearance of virus.
📌https://ajp.amjpathol.org/article/S0002-9440(23)00056-1/fulltext
📌 https://ajp.amjpathol.org/issue/S0002-9440(22)X0007-2
Espanha proibiu há 3 anos. Malta está em processo legislativo. Portugal é um dos 3 países da UE que, além de permitir esterilização forçada de mulheres com deficiência, o permite em menores.
Esta violência tem de acabar.
🐦🔗: https://n.respublicae.eu/joseggusmao/status/1666467965263290368
‘In the winter of 1750, Jean-Jacques Rousseau threw away his watch. “Thank heavens,” he remembered exclaiming after this sublime gesture, “I shall no longer need to know what time its!”’
- Peter Gay, ‘The Enlightenment, the rise of modern paganism’.
#Books #BookClub #HistoryBooks #Philosophy #Bookshelf #bookstodon
A vital post by the @MIT head of admissions:
https://mitadmissions.org/blogs/entry/reaffirming-our-commitment-to-diversity/
The Supreme Court is most likely about to gut the (narrow) use of race in college admissions. Doing so will further concentrate power in majority white upper income cohorts while reducing both excellence and social welfare. Dean Schmill brings the receipts. Read the footnotes, btw: they contain those receipts.
A comprehensive conversation on #LongCovid with Hannah Davis
https://erictopol.substack.com/p/hannah-davis-a-360-on-long-covid w/ transcript
Ouch
“What Keir Starmer offered was Corbynism with competence, that was the basis of his leadership bid,” he says. “What he delivered was Blairism without charisma.”
https://www.ft.com/content/f2da2081-5304-4e2b-b9f9-0bc837dbcf21
"Similarly, reproductive aging and women’s health are finally on the scene: several initiatives have recognized not only that reproductive cessation is the earliest aging phenotype, but also that menopause itself (which is about 15 years later than reproductive aging, so not interchangeable) can cause aging, and that mid-life health may ultimately determine future longevity. This, plus the acknowledgment that female animals are important to study in all aspects of biology, may lead to the end of ignoring 50% of the aging population’s needs."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002132
On this day in 1920: Jacques Monod born, won 1958 #NobelPrize for working out function of mRNA #ThisDayInBiotech
Today's #neuroscience news includes the release of the first fully-reconstructed #connectome for the ventral nerve cord (VNC) of the adult #drosophila. This data set, known as the "MANC", is the result of collaboration between the FlyEM team at #HHMIJanelia and teams from the University of #Cambridge and #Google Research. (1/5)
🔬 Discover how to turn your scientific discoveries into real-world products and services that benefit society!
📍 HT's Centre for Innovation and Technology Transfer is organising a one-day training course on #techtransfer and #ThirdMission in the #lifesciences.
🧐 In partnership with Netval and IUSS Pavia.
Register by 28th June 👉 https://humantechnopole.it/en/trainings/technology-transfer-for-beginners-from-scratch-to-millions/
"In this article – which builds on a preprint we posted in March 2022 (Corneille et al., 2022) – we describe a range of persuasive communication devices that can be used to exaggerate the importance of and/or hide the weaknesses of scientific work, and urge authors to exercise caution when thinking about using such devices"
Antidepressant from engineered fungus. Transferring the #biosynthetic pathway of the #antidepressant orcinol glucoside from #Curculigo orchioides into #Yarrowia lipolytica results in yields >6400x higher than from its natural plant source #PLOSBiology https://plos.io/3J0Px3T
Senior/Laboratory Research Scientist – Protein Biochemist | https://www.crick.ac.uk/careers-study/vacancies/2023-06-06-senior/laboratory-research-scientist-protein-biochemist #proteomics
Interesting addition to the toolbox, if you're working on #microglia:
"We generated a constitutive Cre line controlled by the microglia signature gene Crybb1 that produced nearly complete recombination in embryonic brain macrophages (microglia and border-associated macrophages [BAMs]) by the perinatal period, with limited recombination in peripheral myeloid cells."
https://www.cell.com/immunity/fulltext/S1074-7613(23)00040-7
Be there or be square (if you're Lisbon):
Exposição "Oubliette", inaugura 6ª feira dia 16 Junho às 18h30 na Biblioteca Camões em Lisboa. Pieces by Ana Jotta, Constança Arouca, Jorge Nesbitt & Madalena Parreira
Texts by H. Manfredsenjensen
Opening on Friday, June 16th at Biblioteca Camões, Lisbon (Largo Calhariz 17), 18h30.
"We have established a #Helicobacter-induced accelerated disease progression mouse model, which involves infecting mice deficient in the myeloid differentiation primary response 88 gene (Myd88-/-) with H. felis. Using this model, we report here that that progression of H. felis-induced inflammation to high-grade dysplasia was associated with activation of type I interferon (IFN-I) signaling pathway and upregulation of related downstream target genes, IFN-stimulated genes (ISGs)." #Preprint
https://www.biorxiv.org/content/10.1101/2023.06.04.543598v1?med=mas
"Typing and retyping as if you know where you're going is a version of what therapists tell you to do when they suggest that you try changing from the outside in - that if you can't master the total commitment to whatever change you want to make, you can at least do all the extraneous things connected with it, which make it that much easier to get there."
- Nora Ephron.
https://www.nytimes.com/1986/11/09/books/revision-and-life-take-it-from-the-top-again.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com