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One of the embryo model studies I wrote about the other day is officially published in Nature: nature.com/articles/s41586-023 And one that I didn't write about is also published there: nature.com/articles/s41586-023 So that's 5 embryo models, w/more to come...

The Company of Biologists is excited to announce the launch of its new mastodon instance @biologists.social, on which you can now find all our journals and community sites. We look forward to sharing more news about this new community in the coming days.

Back to the zebrafish fin at #GRCdevbio23, with @HeatherBleu (@uoregon) discussing the role of calcium signalling in controlling the regeneration of the size and shape of organs, using the longfin zebrafish mutant published in @Dev_journal
doi.org/10.1242/dev.199384

New TG mouse model for infection

"In this study, we report an inducible, transgenic hACE2 mouse line and showcase three examples for specifically expressing hACE2 in three different lung epithelial cells, including AT2 cells, club cells, and ciliated cells. Moreover, all these mice models develop severe pneumonia after SARS-CoV-2 infection."

pnas.org/doi/10.1073/pnas.2207

'The first popular English-language science books came to India in the mid-20th century. Even today, a majority of popular science books in Indian bookstores or online marketplaces are in English and written by foreign authors. The lack of Indian stories and perspectives is stark. While bestsellers in politics, cultural fiction, entertainment, and sports dominate the Indian market and have won prestigious international awards, compelling literature on Indian science and scientists is rare. It also likely accounts for the limited penetration of any popular book on science.'

nature.com/articles/d44151-023

“Equity in science is not a political issue; it’s good science.” The authors caution that in order to move equity to the center of scientific research, “we must first recognize and acknowledge whom our scientific and institutional processes harm and how,” noting that acknowledging this harm “is the first step” towards positive change.'

forbes.com/sites/marybethgasma

One of the many reasons actual doctors and scientists shouldn't debate RFK Jr: because he constantly lies about everything, even simple indisputable facts.

He claims comparative studies aren't done on vaccines.

Yes, they are. Here's one showing the efficacy of the COVID vaccine, and one showing autism is *less* common in kids who received the MMR vaccine.

His whole shtick relies on repeating lies until the audience starts thinking they might be true. No use in helping him.

They were here indeed .
A great week teaching MD PhD students of the multi-institutional EMERALD MD PhD program for the second year, this time at the Instituto Gulbenkian de Ciencia in Lisbon (last year at Centre for Genomic Regulation (CRG) Barcelona). Thanks to David Brena, PhD, Damjana Kastelic, Luis Moita, Gabriel G. Martins, Tiago Paixao & Ricardo Leite for making it all happen.

The first part was a one day workshop on modern scientific publication that David del Álamo and I designed. The rest was discussing the interplay of basic science and medical progress with a wonderful group of students.

"Despite this lower baseline phosphosignature, CD14+ monocytes and CD1c+ DCs from both patients and healthy donors showed very similar activation in response to atherosclerotic plasma. However, when exposed to healthy plasma, only immune cells from patients were activated, suggesting they have an intrinsic inflammatory capacity in response to the same stimulus."

nature.com/articles/s44161-023

This preprint from Groza et al. (Helge Ewers lab) looks really interesting. Exploring how particles (such as virions) gain entry to cells. Really neat application of synthetic tools to show that overcoming energy for membrane deformation is the key step to endocytosis.

biorxiv.org/content/10.1101/20

#CellBiology #MembraneTraffic #Virology

“It’s not surprising the WSJ is disinclined to entertain the real lesson of the story: that confident idiots who think regulation is for cowards can end up getting themselves killed, and taking innocent people with them.” # currentaffairs.org/2023/06/the

Post-Doctoral Fellow (PDF) positions in Biology

Seoul National University

Prospective applicants should first send a brief expression of interest and a curricula vitae (CV) with contact details of two referees.

See the full job description on jobRxiv: jobrxiv.org/job/seoul-national

#Scien...
jobrxiv.org/job/seoul-national

#Introduction

Hello #BiologyMastodon We are the British Society for Developmental Biology.

We are here to immerse ourselves in the #DevBio Mastodon universe and to keep you informed about the meetings we organise, the grants we give out and all the other good things that we do.

'This is a vision of hell. It is also a glimpse of the future. The Institute for Economics and Peace has estimated that by the middle of the century more than a billion people will be at risk of displacement because of ecological threats.'

lrb.co.uk/blog/2023/june/ever-

If you have never heard of her, go to YouTube and find her films: #LotteReininger long before Disney invented animated films - of opera, novels, fairy tales...
When visiting #UniversitätTübingen for a talk i accidentally stumbled into her collection at a local museum - impressive to see the original cut out silhouettes

This is Papageno based on #mozart #magigflute
m.youtube.com/watch?v=h4uUchB4

#Ainime #cinema #animations #WomenInFilm

If there ever was a need for a perfect example of why ethics approval really is crucial in human research, Didier Raoult would be that example! Raoult is a threat to any patient or volunteer and a disgrace to all science.

"Didier Raoult : 30 years of unregulated experiments on humans"
lepoint.fr/sante/didier-raoult

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