Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Elect enough politicians of the kind that now call themselves "Republican" and this kind of thing will happen more and more: Ban this, ban that, ban practically anything to demonstrate they are Tough-Minded and In-Control-of-Everything. If they were also efficient, they would skip ahead, stop calling themselves "Republican" and finally, accurately call themselves "Fascist". https://bookriot.com/hoopla-overdrive-libby-now-banned-for-those-under-18-in-mississippi/

@embojournal Should there then be a clear correlation to #microbiome composition and short fatty acid concentrations in patients? Is this data out there already? @cyrilpedia @gpollara @EMIL_DKFZ @dkfz

#Neurology @thelancet Earlier menopause refers to menopause that occurs before the median age of natural menopause (age 50 years) & premature menopause refers to menopause that occurs before age 40 years. Emerging shreds of evidence indicated that earlier menopause, particularly premature menopause, irrespective of its spontaneous or surgery-induced nature, might be associated with increased risks of #cardiovasculardiseases, #sleepdisorders, #psychiatricdiseases ( #dementia )& other sequelae.

@thelancet Most of these findings implicated an oestrogen deficit mechanism leading to tissue or organ dysfunctions
📌 https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00210-9/fulltext#section-3d6acba1-acea-4be2-8dc9-b7e14e5b6583
📌 https://www.thelancet.com/journals/eclinm/issue/vol60nonull/PIIS2589-5370(23)X0005-4

Recommended resource:

#covid @whn
https://www.panaccindex.info/p/what-sars-cov-2-does-to-the-body

This sounds cool and promising: ‘Klotho itself cannot cross the barrier from blood to brain’, so this memory improvement might be a general improvement in ageing that shows up in brain function? https://www.nature.com/articles/d41586-023-02214-3

#aging #ageing #agingbiology #ageingbiology

Testing the #academia outreach here on Mastodon. Please boost if you think you know others who might know.

I'm looking for some good light undergraduate-level books/articles in English about Taiwan under the Japanese and during the White Terror. History, culture, I would even love recommendations of short fiction if you have any.

Thanks

#Taiwan #Colonialism #WhiteTerror #JapaneseColonialism #History #CulturalStudies #Literature

@thelancet ‘Opioids should not be recommended for acute non-specific low back pain or neck pain given that we found no significant difference in pain severity compared with placebo. This finding calls for a change in the frequent use of opioids for these conditions’
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00404-X/fulltext

📖 #MondayMusings with @PeerCommunityIn 📖

"The relationship between impact metrics and #APCs evidences that publishers fix fees 𝐝𝐞𝐩𝐞𝐧𝐝𝐢𝐧𝐠 𝐨𝐧 𝐭𝐡𝐞 𝐫𝐞𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧 𝐚𝐬𝐬𝐢𝐠𝐧𝐞𝐝 to journals by peers"
#ScholarlyCommunication

#Science is funded by public money.

We need new #ScholarlyCommunication models like PCI or diamond #OpenAccess journals to give money back to research and promote #ResearchIntegrity #OpenEdu #OpenScience #AcademicTwitter

https://onlinelibrary.wiley.com/doi/10.1002/leap.1558#leap1558-bib-0106

If you gain biological insight from #microscopy images, then check out the ‘Beyond pretty pictures’ subgroup at #CellBio2023, with tandem talks highlighting collaborative research between experimental & computational biologists.
Abstract deadline: 1 August
https://focalplane.biologists.com/2023/07/06/beyond-pretty-pictures-subgroup-at-cell-bio-2023/
#CellBiology #bioimageanalysis #conference

What doesn’t kill you makes you younger: damage-induced tissue regeneration resets the clock for elderly flatworms. 👩‍🎤🎵

Really entertaining preLight prepared by Sophia Friesen covering work from the #GuoLonghua Lab #UMich. #preprint

#development #physiology #ageing

#preLight 👉 https://prelights.biologists.com/highlights/regeneration-leads-to-global-tissue-rejuvenation-in-aging-sexual-planarians/

In Japanese folklore kaze no kami are invisible, evil spirits believed to cause sickness and suffering by travelling on, and controlling, the wind. When they encounter humans, they exhale toxic clouds of yellow breath, causing all who breathe it in to become ill. Despite this, these spirits were sometimes enshrined as gods by those whose livelihoods depended upon favourable winds.
#MythologyMonday #yokai #mythology #JapaneseFolklore #JapaneseArt #ukiyoe @mythology @folklore
1/2

SIB Swiss Institute of Bioinformatics - Comparative Genomics Course 2023
https://www.sib.swiss/training/course/20230830_COMGE
The aims of this course are to (i) explore key evolutionary concepts, (ii) examine different methodological approaches, and (iii) gain hands-on experience in eukaryotic comparative genomic analyses.
Application deadline:
26 July 2023

Symposium on applied quantum computing at the Institute for Advanced Studies: opportunities and limitations in diverse fields from #chemistry to #PersonalizedMedicine #quantumcomputing @MunichQuantum @fraunhofer @helmholtz @hereon @association

Gut #microbiota regulates blood-#cerebrospinal fluid barrier function and Aβ pathology
Roos Vandenbroucke and colleagues
The gut microbiota promotes blood-cerebrospinal fluid (#CSF) barrier integrity by regulating the subcellular localization of tight junctions and reduces #Alzheimer's disease pathology
https://www.embopress.org/doi/full/10.15252/embj.2022111515

on day 87 of drawing animals I was tired and completely underestimated how hard giant #Isopods would be to draw for me. I am still a bit confused about it. Might try them again some time when I am more awake, maybe that really _was_ the thing that tripped me up. Still, I did not falter! And still sticking with the marine theme for #Mermay.

#Ink #Art #Invertebrates

Come for the story about how GLP-1 receptor agonists — the hot new diet drugs like Wegovy — were developed. Stay for the cocktail-nicking vervet monkeys & what they tell us about the drugs' addiction curbing capacities. https://www.statnews.com/2023/07/10/new-weight-loss-drugs-wegovy-food-cravings/

'Here, we analyzed #lysosome subcellular distribution in micropatterned patient-derived melanoma cells and found that lysosome spreading scales with their aggressiveness.'
#Preprint #Melanoma

https://www.biorxiv.org/content/10.1101/2023.07.07.548108v1

'This proof-of-concept study suggests that bNAbs may represent a promising treatment modality for infants and children living with HIV-1. Future studies using newer bNAb combinations with greater breadth and potency are warranted.'

https://www.science.org/doi/10.1126/scitranslmed.adh0004?adobe_mc=MCMID%3D32606866948369690911249990612432038778%7CMCORGID%3D242B6472541199F70A4C98A6%2540AdobeOrg%7CTS%3D1688573056