Thiago Carvalho @cyrilpedia@social.cleverlibre.org

@schoppik Thanks for including me in this list of awesome people! 💖

@AllenNeuroLab @cyrilpedia @NicoleCRust @dgoldsmith @mekkaokereke @talia_christine

Happy to have joined synapse.cafe. The Effort Lab is a neuroscience/psychophysiology lab at Liverpool John Moores University, UK, examining determinants and mechanisms of effort investment in goal-directed behavior. #introductions

Hello again Mastodon/fediverse, any good topics about the brain to discuss today?? 😅

Bioinformatics Specialist
City of Hope

See the full job description on jobRxiv: https://jobrxiv.org/job/bioinformatics-specialist/?feed_id=52805

#ScienceJobs #hiring #research
Duarte #UnitedStatesUS #Bioinformatician #ResearchTechnician #Researcher #Scientist
https://jobrxiv.org/job/bioinformatics-specialist/?feed_id=52805

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807639

With commentary by @michael_hoerger

via @MoriartyLab and @kashprime

“New study in @JAMANetworkOpen shows that the reintroduction of universal #masking in #Ottawa #schools in spring 2022 reduced student absenteeism.

#Students gained nearly 2,000 days of learning in the schools studied.

The study likely considerably underestimated the real benefit of masking and enormously underestimated the potential benefit of masking.”

🙉🙈Ignorance is not bliss.
'The virus is still lurking and it's dangerous to be complacent. It’s a long time since many had their booster jabs, and the poor weather in July may have encouraged crowding in poorly ventilated spaces.' 💯Prof @LawrenceYoung11 https://www.telegraph.co.uk/news/2023/07/29/covid-19-uk-infections-virus-coronavirus-rise-booster/

The most recent Podcast I produced for EMBO was with Pavel Tomancak (and EMBO's Thomas Lemberger). One detail that might get missed in a wide ranging conversation about science, policy, science fiction and more was Pavel's passing comment on how one important consideration in his decision to return to Europe after a very productive time at UC Berkeley were serious reservations about the US healthcare system.
#Drosophila #OpenScience #DevelopmentalBiology #EMBOPodcast

https://www.embo.org/podcasts/who-reviews-the-reviewers/

'Radick uses counterfactual history to perform an experiment. He outlines a curriculum for an introductory biology class that does not begin and end with Mendelian inheritance, but instead emphasizes developmental contexts. Students who took this class — Radick ran the experiment at the University of Leeds, UK — came away with a less gene-centred and a more enquiring approach to biology than did those who took a more Mendel-focused course (A. Jamieson & G. Radick Sci. Educ. 26, 1261–1290; 2017).'

https://www.nature.com/articles/d41586-023-02310-4

@cyrilpedia 8th World Conference on #ResearchIntegrity produced a statement to try to address this issue - https://www.wcrif.org/guidance/cape-town-statement

When will the British follow ?
Their museums are full of plundered objects from slave nations and the RF even wears plundered jewels
@humanrightswatch @humanrights @PIL@mastodon.lawprofs.org @pil@a.gup.pe

LAG3 ICIs

"With this approval, LAG-3 became the third checkpoint inhibitor to show efficacy when targeted in the clinic, The response profile of Opdualag is comparable to the ipilimumab/nivolumab (anti-CTLA4/anti-PD-1) combination (47.7% versus 49% 12-month PFS), although 59% of patients had severe adverse events with ipilimumab/nivolumab compared with only 18.9% with Opdualag"

#immunology #Immunotherapy #checkpointinhibitors

https://www.nature.com/articles/s41590-023-01569-z

'We compare collective performance in structured information–sharing networks to collective performance in independent control groups, and find that networks significantly reduce clinical errors, and improve treatment recommendations, as compared to control groups of independent clinicians engaged in isolated reflection.'

https://www.pnas.org/doi/10.1073/pnas.2108290120

"Heat damage to underground cables"? WTF!!!

Italian city ‘brought to its knees’ by power cuts caused by #heatwave

by Jasper King, Tuesday 25 Jul 2023

"Hundreds of thousands people are facing blackouts and are without electricity in #Sicily during a scorching heatwave.

"Temperatures on the Italian island have soared to 47.6°C, with warnings Catania has been ‘brought to its knees’ by the power cuts.

"It is believed the power cuts have been caused by heat damage to underground cables.

"Between 200,000 to 300,000 people have been impacted by water pumps stopping but the issue was resolved on Monday morning."

https://metro.co.uk/2023/07/25/huge-blackouts-on-sicily-impact-half-a-million-people-19186076/

#Blackouts #Italy

Researchers found both compositional & functional gut #microbiome differences in people with various types of arthritis and I like their caution in concluding these are probably a RESPONSE to system-wide inflammation, rather than the cause of it.
https://www.science.org/doi/10.1126/scitranslmed.abn4722

#rheumatoid #ankylosing #psoriatic #arthritis

And another paper likely to get the proteomics crowd hitting their keyboards in a frenzy :-)

Proteome-wide copy-number estimation from transcriptomics | https://www.biorxiv.org/content/10.1101/2023.07.10.548432v1.full.pdf+html #proteomics

If you're considering grad school in Portugal, don't forget to inquire about housing:

'Like so many people in Portugal, where rental prices make a mockery of the low salaries, Custódio lives through a monthly agony when it comes to covering the costs of her flat. Despite a good job in human resources, she earns €930 (£795) a month after tax – of which €700 goes on rent.'

https://www.theguardian.com/world/2023/jul/29/portugals-bid-to-attract-foreign-money-backfires-as-rental-market-goes-crazy