Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Location location location

"Here, we show that NET1 mRNA location in combination with the rate of its translation can influence the ability of competing domains to determine the targeting of the newly synthesized protein, by favoring binding to specific partners. This RNA-based partner-selection mechanism provides a robust means of controlling protein function."
#MolecularBiology #Translation #RNA

https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00514-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

'The spending underscores that trial attorneys are still pursuing payouts from Bayer five years after a jury initially awarded $289mn in a Roundup case. The landmark award triggered thousands of additional mass tort claims that exposure to glyphosate, the active ingredient in Roundup, caused non-Hodgkin lymphoma.'

https://www.ft.com/content/36f28381-1cc2-4ce7-9053-7c172605d08c

'Across America right now, parents face a possible nightmare: taking a sick child to the doctor, only to be told at the front desk that their health insurance is no longer valid. The reason is that millions of low-income American families have lost Medicaid benefits because they have to jump through an unexpected administrative hoop, resulting in a slow-burning crisis.'

https://www.theatlantic.com/family/archive/2023/08/health-insurance-losing-medicaid-coverage-verification-disenrollment/674929/

Sensory neuroscience meets climate change.

"Dungeness crabs hunt by flicking their chemical-detecting antennae to and fro. Sensing the water—the underwater equivalent of sniffing the air—is a well-known strategy for homing in on potential prey. But that timeless tactic appears to be at risk, as new research shows that climate-change-induced ocean acidification seems to cause Dungeness crabs’ antennae to falter."

https://www.theatlantic.com/science/archive/2023/08/climate-change-ocean-acidification-crabs/674932/

'So why did artists pivot from venerating powerful people and institutions to images of peasants engaged in unremarkable activities like walking, dancing, working and eating?'

https://aeon.co/videos/why-european-artists-shifted-their-focus-from-power-to-peasants-in-the-16th-century

“Mire usted”, le contestó, “cuando tomé posesión me dijo el rector: Tiene usted ahora que ir al Sr. arzobispo para ponerse a su disposición.

—¿Y por qué?, dije yo.

—Hombre, es lo que hay que hacer, ¿no le parece?

—Pues me he venido sin más [a Madrid] y que le den por culo al arzobispo y al rector”.

https://elpais.com/ciencia/2023-08-06/el-enigma-del-doctor-arteta-el-genio-de-la-patologia-que-renuncio-a-ser-catedratico-que-le-den-por-culo-al-arzobispo-y-al-rector.html

'Our results show that despite different building materials, comb configurations, and 179 million years of independent evolution, honey bees and social wasps have converged on the same solutions for the same architectural problems, thereby revealing fundamental building properties and evolutionary convergence in construction behavior.'

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002211

'When my college roommate concluded with a personality test that I was the “creative” type, the rest of my friends said that couldn’t be right, because “I was a scientist and therefore was not creative.” When I tell people I’m in a chemistry Ph.D. program, they often respond with something along the lines of, “I could never do that because I am more of the creative type.”

https://www.science.org/content/article/how-centering-my-creativity-helps-my-science