'For Le Guin, writing was a “willingness to relinquish control, an act of trust.” Her universes were born of the belief that her imaginative instincts would take her where she needed to go — out among her fellow aliens and the stars.'
https://www.nytimes.com/article/ursula-k-leguin-best-books.html
Madrid vermuterias:
"Two gentlemen, in suits and hats, one with a cane, sat next to each other at the far end of the bar. They looked dressed from an era when people didn’t wear T-shirts and never left the house without a hat.
“I have been sitting in this seat every day for 50 years,” said Jaime, 91."
https://www.nytimes.com/2023/08/16/travel/vermouth-madrid-best-places-to-drink.html
Lithographic print on wood 12x20cm
#Print #Printmaking #Art #ArtGallery #lithography #Handmade #artmastodon
'Meditations on Mortality and Cinema: Kurosowa, Scorsese, and Friedkin'
A bittersweet cinematic awakening awaits many filmmakers as they approach the end of their lives.
“Just when you learn how to do it, you're too old. Except in your dreams."
Read: https://colehaddon.substack.com/p/a-meditation-on-mortality-in-cinema
#film #movies #cinema #filmmaking #screenwriting #directing #MartinScorsese #AkiraKurosawa #williamfriedkin #art #aging #mortality #lifelessons
A district court judge upheld a US Copyright Office finding that artwork created by AI isn't eligible for copyright protection because it lacks human authorship (Winston Cho/The Hollywood Reporter) http://www.techmeme.com/230818/p18?utm_source=dlvr.it&utm_medium=mastodon#a230818p18
"By targeting graduate school applicants, application assistance programs are a powerful and precise method for increasing the representation of minoritized groups in the sciences. These interventions can have a high impact on career outcomes and in remedying the discrepancies between the social and cultural expectations of students and graduate school admissions committees."
"The (re)appreciation that true insight into neural function depends reciprocally on an in-depth understanding of the underlying structure(s) has driven a surge in efforts to develop novel imaging techniques. In fact, keeping track of these approaches, which continue to emerge at a staggering pace, has become a challenge by itself."
#neuroscience @PLOSBiology
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002221
"In a new study published Thursday in the journal Science, a group of paleontologists that analyzed fossil records at La Brea Tar Pits, a famous excavation site in Southern California, concluded that the disappearance of sabertooth cats, dire wolves and other large mammals in this region nearly 13,000 years ago was linked to rising temperatures and increased fire activity spurred by people."
The Massive Open Online Course (MOOC)
from @sthlmresilience
"Transforming Development: the science and practice" of resilience" has been updated and is now open
https://www.edx.org/learn/social-science/sdg-academy-transforming-development-the-science-and-practice
@enochmm @VaryIngweion mira esta gráfica. es lo que necesitamos hacer para mantenernos en 1.5ºC al 50% de probabilidad sin overshooting. En 6 años el mundo tendría que dejar de emitir el 48% de las emisiones. En 14 años, el 80%. En 24 años, el 99%. ¿Podemos afirmar que estamos avanzando hacia eso? Si la respuesta es no, entonces no hay desacoplamiento suficiente. De hecho la respuesta no es "no", es "no, ni de lejos".
Blaise Pascal died #OTD in 1662. His earliest mathematical work was on conic sections; he wrote a significant treatise on the subject of projective geometry at the age of 16. He later corresponded with Pierre de Fermat on probability theory, strongly influencing the development of modern economics and social science. In 1642 he started some pioneering work on calculating machines, establishing him as one of the first two inventors of the mechanical calculator.
Postdoctoral Research Fellow: Alternative Splicing in Pancreatic Cancer Metastasis
Moffitt Cancer Center
See the full job description on jobRxiv: https://jobrxiv.org/job/postdoctoral-research-fellow-alternative-splicing-in-pancreatic-cancer-metastasis/?feed_id=55734
#ScienceJobs #hiring #research
Tampa #UnitedStatesUS #PostdoctoralFellow #Researcher
https://jobrxiv.org/job/postdoctoral-research-fellow-alternative-splicing-in-pancreatic-cancer-metastasis/?feed_id=55734
FDA’s ‘Standing’ problem: Why the mifepristone court case could lead to more challenges to product approvals
The moving story of Carol Jennings, APP and Alzheimer's
In all my years as a brain researcher, I didn't think to sit down and learn the stories of individuals afflicted with brain dysfunction until I sat down to write a book. Learning their stories has been one of the most impactful parts of this experience.
Among them: Carol Jennings. In an era in which the causes of Alzheimer's were not thought to be genetic, Carol's father and four of his siblings were all diagnosed with the disease at the ages 54-58. She started writing letters to Alzheimer's researchers wondering if her family could contribute to some type of study. One of those letters was written to John Hardy and it set off a chain of events that changed the course of Alzheimer's research for the next 30 years.
"Dear Sir, I was very interested to read of your research in the Alzheimer’s Disease Society News and think my family could be of use ... please contact me at the above address if you think we could be of help." April, 1986.
That letter led to the discovery of a single point mutation in the gene APP that leads to the protein beta-amyloid. It was a key step toward Hardy and others launching the amyloid cascade hypothesis, which in turn led to the new Alzheimer's drugs. (While their effectiveness thus far is questionable, they are a necessary step).
Carol spent the next 30 years as a patient advocate. She refused to be tested for the gene herself absent a cure. Tragically, she was diagnosed with the disease in 2012.
Here's more about Carol and her devoted husband and caregiver, Stewart.
https://www.alzheimers.org.uk/blog/honouring-couple-dementia-their-contributions-research
(Watch the movie. Have tissues ready).
In case you missed it, this was a great conversation with Pavel Tomancak & @tlemberger for the #EMBOPodcast.
Everything from the early days of open science to tips on classic Czech science fiction.
#EMBOPodcast #SciComm #SciencePodcast #DevelopmentalBiology
Take the ability to block away, and Twitter immediately becomes utterly unusable for anyone who doesn’t revel in being overwhelmed by an avalanche of racist, misogynistic, bigoted filth - and that’s intentional, of course. An incitement of abuse.
https://variety.com/2023/digital/news/elon-musk-x-twitter-block-feature-delete-1235699759/
Biological Imaging Development CoLab (BIDC) Director UCSF
UCSF
Dream of spearheading innovative microscopy research? Lead our Biological Imaging Development CoLab team to new heights in scientific discovery.
See the full job description on jobRxiv: https://jobrxiv.org/job/ucsf-27778-biological-imaging-development-colab-bidc-director-ucsf/?feed_id=55725
#ScienceJobs #hiring #research...
https://jobrxiv.org/job/ucsf-27778-biological-imaging-development-colab-bidc-director-ucsf/?feed_id=55725
During WWI, Marie Curie created a vehicle that contained a hospital bed, a generator, an X-ray machine and photographic darkroom equipment. These “petite Curies" (below) could be driven right up to the Front. Curie also helped train 150 women as radiology technicians.
#histmed #histsci #WWI #warhistory #war #medhist #science #womeninstem #womenshistory #histodon #histodons #twittermigration #twitterexodus
'Mère Ubu, inspirada en la sátira Ubu rey, del autor francés Alfred Jarry, es eco, para Miró, de la crueldad del déspota, memoria de la dictadura franquista y recordatorio de que la tentación autoritaria sigue anidando en nuestras calles.'
https://elpais.com/opinion/2023-08-19/el-simbolismo-de-la-mere-ubu-de-miro.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com