'Es un tipo muy duro. Meticuloso. Comprometido. Y ese espíritu se refleja en sus proyectos, como Amazônia, al que pertenecen las imágenes de estas páginas: travesías por la selva amazónica a lo largo de varios años para retratar la tragedia ecológica y humana de la destrucción del pulmón del planeta.'
https://elpais.com/eps/2023-08-30/sebastiao-salgado-y-la-salvaje-poesia-del-amazonas.html
The loss of large-bodied #wildlife from tropical forests reduces their #carboncapture potential. This #PLOSBiology Perspective argues that carbon-based markets that incentivize wildlife #conservation can generate revenues to support needed #forest and #hunting management.
https://plos.io/44vBE5q
'But why should you see it, or see it again? Why should you (still) care? These are fair questions to ask of any consensus masterpiece — skepticism is what keeps art alive, reverence embalms it — and especially apt in the case of “Bicycle Thieves.” The movie is about seeing and caring, about the danger of being distracted from what matters. The tragedy it depicts arises partly from poverty, injustice and the aftereffect of dictatorship, but more profoundly from a deficit of empathy.'
https://www.nytimes.com/2020/08/13/movies/bicycle-thieves-italian-neorealism.html
'The US government named 10 of the best-selling drugs as the first to face tough price regulations in a bid to slash healthcare costs, marking the biggest shake-up for the pharmaceutical industry in decades.'
https://www.ft.com/content/fa9b0422-6f93-4703-9358-6396660f63b6
'Braxton, who is Black, decided to go to the town hall and talk to Stokes, who is white, in person. He told Stokes that he would need a key to the town hall to begin his duties. Stokes acquiesced and gave him a key, but when Braxton entered the building, he found that town hall had been stripped of its records, beyond a couple boxes of discarded items that looked like trash. He also said he noticed that Stokes had given keys to friends of his, people who were not council members and had no official business with the city, who were walking in and out of the building.'
https://www.theguardian.com/us-news/2023/aug/26/black-mayor-alabama-town-locked-out
Is #CaloricRestriction the only diet that improves aging health? @Dorottya_Horkai @HouseleyLab &co show that dietary change from glucose to galactose, without restriction, can result in healthy #aging in yeast #PLOSBiology https://plos.io/44xS3GL
'New tracking tools are also helping us to scale up from spatiotemporal analyses of behavioral components to a systems-level view of the whole. The systems approach focuses on structure–function relationships, moving from cause-and-effect thinking to synergistic thinking, by emphasizing interactions, linkages, and integrated phenotypes'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002264
TOR-mediated Ypt1 #phosphorylation regulates autophagy initiation complex assembly
The Rab #GTPase #Ypt1 serves as a bridge that connects environmental sensing to the formation of the #autophagy initiation complex.
1/2
Great work on #mpox #virus ( #MonkeyPox) from Lisa Bauer, Debby van Riel, & Oliver Harschnitz:
"We found that MPXV infects and replicates more efficiently in astrocytes and microglia compared to cortical neurons, which unlike glial cells showed activation of distinct antiviral programs that may confer differential susceptibility to #MPXV."
from:
"Dissecting the neurotropism and neurovirulence of MPXV using human stem cell-based models"
https://doi.org/10.1101/2023.08.25.554849
A fun read from Adam Mastroianni on the recent #HonestyPapers #AcademicChatter controversy
https://www.experimental-history.com/p/im-so-sorry-for-psychologys-loss
Imagine if someone told you that 60% of your loved ones had died in a plane crash... It would be insane to only remember the 60% statistic and then, whenever someone asked you who died in that horrible plane crash, respond, “Hmm, you know, I never really looked into it. Maybe, um, Uncle Fred? Or my friend Clarissa? It was definitely 60% of my loved ones, though, whoever it was.”
FYI
'That said, the Food and Drug Administration has extended the expiration dates for certain brands of tests. You can check a test by finding the lot number (typically found right by the expiration date) and cross-referencing it at this F.D.A. website.'
https://www.nytimes.com/2023/08/29/well/live/covid-test-expiration.html
'With hospitalisation rates low but rising, experts said Covid-19 cannot yet be treated as a seasonal virus like flu. The US Centers for Disease Control and Prevention warned last week that a new sub-variant, BA. 2.86, may be more able to cause infection in people who have previously had Covid-19 or been vaccinated against it, and urged the vulnerable to wear masks in public places.'
https://www.ft.com/content/5ec35a44-eadd-47de-a325-4a5004bc36c5
No talking in the library, please! Reading and research needed silence to protect the concentration of those using the library for knowledge production. However, this was moment of not being quiet by these two men in the @hab_wf in 1654. #HAB_WF A short #BookHistory thread, part 5.
'Picking out proteins and sending them into the vicious shredder that is the proteasome is a completely new mode of action for drugs, and there are many examples of it leading to effects that you just don't see (can't see!) with traditional small-molecule inhibitors. But as these things get further and further into development, and as more and more effort has been poured into them in both industry and academia, details inevitably emerge that make the whole picture more complicated.'
https://www.science.org/content/blog-post/unexpected-effects-protein-degradation
@cyrilpedia Our lab recently catalogued our biggest energy slurpers. The -80C freezers easily came out on top, 10s of kWh/day according to the data sheet. Computation came as a surprising second, and we don't have any clue what the terribly insulated 1960s building costs to keep moderately warm in winter.
My previous institute ran a "get a new -80 freezer for free if you scrap two old ones" challenge for a while. Apparently the new freezers paid for themselves within a couple years.
'Implementing a series of sustainable practices in health research could help the field to reduce its hefty carbon footprint, according to a report commissioned by health-research funder Wellcome.'
'Here, once again, my personal landscape shifted and the possibility of a career in science seemed beyond my reach. I struggled to sleep at nights. I even tried distracting myself with daily 7 mile runs, every pounding step the question echoing: What do you do when you don’t know what to do?'
“But the analysis discovered one major change: The incomes of the rich grew much faster in countries where tax rates were lowered. Instead of trickling down to the middle class, tax cuts for the rich may not accomplish much more than help the rich keep more of their riches and exacerbate income inequality, the research indicates.”
#tax #taxes #inequality #rich #middleclass
https://www.cbsnews.com/news/tax-cuts-rich-50-years-no-trickle-down/
'From their first appearance in the U.S., the syringe tides were a ready-made tabloid sensation, and a shocking visualization of the perils of a throwaway society. In the years that followed, major efforts would be taken to reduce Americans’ solid-waste production and protect its shores. But the steel-and-plastic flotsam raised a more specific warning, too, about the increasing and deliberate wastefulness of the American health-care system. That concern went unheeded at the time.'
Postdoc and Postgrad Positions in Computational Biology, Human Genetics, an
Yale University School of Medicine
Postdoc and postgrad positions open in Dr. Renato Polimanti’s group at the Yale University School of Medicine
See the full job description on jobRxiv: https://jobrxiv.org/job/yale-university-school-of-medicine-27778-postdoc-and-...
https://jobrxiv.org/job/yale-university-school-of-medicine-27778-postdoc-and-postgrad-positions-in-computational-biology-human-genetics-an/?feed_id=57050
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com