Comparing cytoarchitectural subdivisions of #BrocasArea in humans & #chimps: @gagdiez @FriedericiLab &co find that BA44 expanded from a purely action region to a bipartite system (action-related posterior & #syntax-related anterior) in humans #PLOSBiology https://plos.io/45D1tSq
'Countering the theory that glioblastoma–synaptic integration may result in physiologically disorganized neural responses, we found task-relevant neural activity within the entire region of the tumour-infiltrated cortex, including cortical regions that are not typically implicated in speech production (Fig. 1b)—a notable finding that indicates tumour-induced functional remodelling of language circuitry. '
Looking forward to our workshop 'Frontiers of Neuromorphic Computing' that will start tomorrow morning at the @MPI_ScienceOfLight Max Planck Institute for the Science of Light.
We are trying to record at least most of the talks and release them later (with some delay) on video.
'The majority (68%) of the candidates are being developed independently or collaboratively by private companies/industry, while 25% are being developed by academic or other non-profit organizations (Fig. 2b). Notably, candidates against HIV and malaria are being developed mostly by academic or other non-profit organizations.'
New* preprint from the lab! 🎉
Synaptic mechanisms for associative learning in the cerebellar nuclei https://biorxiv.org/content/10.1101/2022.10.28.514163v2
These findings raise the intriguing possibility that plasticity within the cerebellar nuclei (and not just the cortex!) has the capacity to support well-timed sensorimotor learning.
Nice collaboration with Robin Broersen, Chris De Zeeuw et al. 🇳🇱🤝🇵🇹
'Here I call attention to evolutionary addiction, whereby a host trait evolves a need for microbes without having been improved by them. Evolutionary addiction should be considered when interpreting microbe-removal experiments, as it is a distinct and potentially common process. Further, it may have unique implications for the evolution and stability of host–microbe interactions.'
https://www.cell.com/trends/microbiology/fulltext/S0966-842X(23)00224-X
'Es una elefanta —abierta de patas— en una habitación. Es una presencia real y, a la vez, un enigma de primer orden. Creemos pertenecer a una sociedad amante del conocimiento, pero no fue hasta el 1 de junio de 1998 —¡1998!— que conocimos la anatomía completa del clítoris, cuando la doctora australiana Helen O’Connell lo publicó en la revista estadounidense The Journal of Urology.'
cc @vagina_museum
'While more effective treatments are developed and someday may become more widely accessible, interventions that promote the personhood and well-being of persons living with dementia—as well as that of their care partners and caregivers—will remain integral to dementia care.'
#alzheimersdisease
#alzheimers
a Portrait of Tenochtitlan, my 3D reconstruction of the capital of the Aztec Empire is released!
I've been looking forward to this for a long time, and I am really curious what all of you think.
Take a look:
http://tenochtitlan.thomaskole.nl
This is about a writer's notebook (and most definitely *not* about a lab book).
"In my view, a good notebook should be at best partially legible - that’s what creates its mystique. It should actively repel the casual viewer, and exude a feral air that unsettles intruders. It should be a disorderly space, defiant of bourgeois convention; a rowdy heath instead of a tidy garden. Its dark magic lies in a series of collisions, the juxtaposition of thoughts that, in any ordinary space, would not go together. The result should be an unruly object, defying polite society."
@gpollara a whistleblower already said it’s been ignored since at least 2019
@Sheencr yes, this smells of U-turn in some way, especially if the problem expands to other schools/hospitals, and certainly if it drags on for longer.
And you can bet there's some investigative journalists working hard looking for the 'smoking gun' showing government wilfully ignored this.
Agree overall, not the last we've heard of this story....
Outrageous, this was pushed back and back, budgets were cut by Sunak and now they fess up they won’t allocate more cash from the existing (already reduced) budget. They have to backtrack on this one.
Jeremy Hunt under fire after Treasury says no new cash to fix Raac in schools
'It's a short list, but it's a big change, because Medicare up until now has been legally forbidden from negotiating drug prices at all, which is a situation that has never made a great deal of sense considering what happens with other national health care systems around the world.'
https://www.science.org/content/blog-post/inflation-reduction-act-s-first-drug-list
'The Webb data, though, revealed that some very large galaxies formed really fast, in too short a time, at least according to the standard model. This was no minor discrepancy. The finding is akin to parents and their children appearing in a story when the grandparents are still children themselves.'
https://www.nytimes.com/2023/09/02/opinion/cosmology-crisis-webb-telescope.html
'In a 2016 article for The Atlantic, Edward Simon explored the sci-fi that was published during and before the peak of the scientific revolution, including such novels as Thomas More’s Utopia, Francis Bacon’s New Atlantis, and Johannes Kepler’s Somnium. Literature helped spark curiosity as new scientific understandings were developing, he explained. “Science fiction alone did not inspire the scientific revolution, but the literature of the era did allow people to imagine different realities—in some cases, long before those realities actually became real,” Simon wrote.'
https://www.theatlantic.com/newsletters/archive/2023/08/science-fiction-technology/675206/
'Once Allende won—in spite of an American-funded campaign of misinformation that depicted him, a man of impeccable democratic credentials, as a Communist stooge—the next step was to try to stop his inauguration. A CIA-financed terrorist group killed General René Schneider, the commander in chief of the army, who was committed to the rule of law. When Allende was nonetheless sworn in on November 3, covert operations were launched to “make the economy scream,” per Nixon’s instructions.'
https://www.nybooks.com/articles/2023/09/21/defending-allende-ariel-dorfman/
#KochNetwork wants to end access to the ballot for groups of Americans who persistently don't vote Republican.
Women, LGBTQ, immigrants, POC, non-Christians, the young, the poor, the middle class, the educated, the literate, the employed...
If #KochNetwork succeeds, the only people allowed to have a vote that matters will be 1000 oil, tech, & media billionaires, foreign & domestic.
#PutinThePoisoner and #PrinceBonesaw look forward to having an ever bigger say in US elections.
'Bipartisan support continued through three reauthorizations of the program. That ended this year, when Republicans took over the House with a slim majority that was beholden to the MAGA wing of the party, which has been looking for opportunities to damage any Biden administration priorities. PEPFAR became a target when the Heritage Foundation released a falsehood-ridden report in May saying the administration was using it as a “vehicle to promote its domestic radical social agenda overseas,” specifically abortion and L.G.B.T.Q. issues.'
https://www.nytimes.com/2023/09/01/opinion/pepfar-abortion-republicans.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com