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"Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it."

cell.com/cell-metabolism/fullt

Three quarters of trusts in England that responded to a survey by The BMJ are still reliant on paper patient notes and drug charts, despite progress towards electronic records and prescribing
bmj.com/content/382/bmj.p2050

'Three hospitals declined to provide the procedure, she said. At the third, “they said, ‘We can’t touch you unless you’re like crashing in front of us,’” Ms. Statton, 26, said in an interview. The hospital’s only suggestion, she said, was “we should wait in the parking lot until I was about to die.”

nytimes.com/2023/09/12/health/

My latest at NM

"Pigs are, prima facie, a good organ source. They are abundant, their overall physiology is very similar to that of humans, as is their size (in this case, size matters), and they can be bred under conditions that limit exposure to pathogens"


nature.com/articles/d41591-023

I hate it when that happens

"He recounts the grudge he held on behalf of his father, Thyestes, whom Agamemnon’s father, Atreus, had tricked into eating his own children."

nytimes.com/2023/09/12/magazin

'However, it is well-established that, compared with other conventional treatments, immunotherapy shows unique efficacy kinetics such as delayed clinical effect and long-term favorable outcome.3 These characteristics may lead to the prolongation of trial duration and make it difficult to accelerate the drug development process.'

thelancet.com/journals/eclinm/

NEWS: IG Threads blocks all searches related to covid and vaccines in the midst of a major covid surge.

Public health experts denounced the platform’s moderation policies, which they say restrict access to critical health information
washingtonpost.com/technology/

"Throughout the tome, Musk’s confidantes, co-workers, ex-wives and girlfriends present a DSM-5’s worth of psychiatric and other theories for the “demon moods” that darken the lives of his subordinates, and increasingly the rest of us, among them bipolar disorder, OCD, and the form of autism formerly known as Asperger’s. But the idea that any of these conditions are what makes Musk an “asshole” (another frequently used descriptor of him in the book), while also making him successful in his many pursuits, is an insult to all those affected by them who manage to change the world without leaving a trail of wounded people, failing social networks and general despair behind them. The answer then must lie elsewhere."

theguardian.com/books/2023/sep

🧬 "Identifying the molecular drivers of #NeuroCOVID is crucial"

How close are we to understanding the roots of this condition? Let's talk about it with our Oliver Harschnitz

#science #sciencemastodon #longcovid #covid #neuroscience

youtube.com/watch?v=nhKkEkDc-F

After thinking it over all week and talking to a bunch of peers, I've made up my mind. Goodbye Twitter. Also, I think it lots more journalists decided to go (it's surprising how many good folks are still there, as I detail), a big chunk of the advocacy sector would leave too. It's time. open.substack.com/pub/theconne

It is so hard to manage infections when the anatomy is not intact

Here in infants with Vesicoureteric Reflux. Give antibiotic prophylaxis:
👉 less UTIs
👉 more antibiotic resistance

Not a straightforward trade-off given the many courses of antibiotic ahead of these young people's lives...
#AMR #IDMastodon #infectiousdiseases #pediatrics #microbiology #antibiotics #reflux #UTI
nejm.org/doi/full/10.1056/NEJM

'If the NIH does decide to support fewer postdocs but with increased pay, it could change the calculus for many labs across the country. Schwetz acknowledges this, and says that leading a smaller lab will hopefully help PIs to provide a better experience for their team members and to focus on a smaller number of projects. Some scientists are looking forward to that kind of future.'

nature.com/articles/d41586-023

"The BMJ asked the colleges to disclose all payments from industry, campaign groups, or patient associations, including the specific amount received from each donor, but they all refused to do so, other than the Royal College of Anaesthetists."

bmj.com/content/382/bmj.p1658

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