Thiago Carvalho @cyrilpedia@social.cleverlibre.org

So #DORA has almost 24k signatures now:

https://mastodon.world/@DORAssessment/111088194624414428

Only 3k of those are from institutions. Globally, the number of academic institutions is close to 90k:

https://higheredstrategy.com/higher-education-institutions-worldwide/

DORA is now 10 years old:

https://sfdora.org/dora-10th-anniversary-events/

At the current rate of about 300 institutional signatories per year, it will take another 140 years until 50% of all institutions have signed DORA.

This is the speed of #openscience

The length of motorways in Europe grew 60% between 1995 and 2020 while railways shrank 6.5%. For every €1 governments spent building railways, they spent €1.6 building roads.

https://www.theguardian.com/world/2023/sep/19/european-governments-railways-road-building-report-motorways-funding-rail?CMP=Share_iOSApp_Other

'However, it is well-established that, compared with other conventional treatments, immunotherapy shows unique efficacy kinetics such as delayed clinical effect and long-term favorable outcome.3 These characteristics may lead to the prolongation of trial duration and make it difficult to accelerate the drug development process.'

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00333-4/fulltext#secsectitle0100

I hate it when that happens

"He recounts the grudge he held on behalf of his father, Thyestes, whom Agamemnon’s father, Atreus, had tricked into eating his own children."

https://www.nytimes.com/2023/09/12/magazine/greek-tragedy.html

'That book’s philosophical themes, however, continued to percolate and eventually emerged in an entirely different form in a series of stories called Artifices (1944). In that collection’s opening story, Borges describes a man who loses his ability to forget.'

https://aeon.co/essays/borges-and-heisenberg-converged-on-the-slipperiness-of-language

'Following Joseph Lister, German surgeons, unlike their French colleagues, used carbolic acid spray to sterilise their tools and operating areas. French surgeons did insist on ‘hygiene’, but by this they meant the provision of adequate bedding and the maintenance of medical supplies, not sterilisation. Death rates for amputations on the French side reached 75 per cent (including toes and fingers) – a shocking figure, given that by 1870 the use of Lister’s techniques in peacetime amputations had resulted in a drop from 50 per cent to 15 per cent.'

https://www.lrb.co.uk/the-paper/v45/n18/christopher-clark/predicamental

Cephalopod ceramics, glazed stoneware by @hunchbacksociety

https://hunchbacksociety.cargo.site/Small-talk

#Ceramics #Handmade #Art #stoneware #artgallery #artmastodon

'Limitations relative to absolute age, time from doctoral degree, and/or duration of postdoctoral training arbitrarily select against early-stage investigators who have taken nonlinear or nontraditional career paths.'

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002291

@thelancet #SARSCoV2 is capable of #neuroinvasion into the hypothalamus through at least 2 distinct invasion routes➡️resulting dysfunction of GnRH-neurons & tanycytes(special ependymal cells in the 3rd ventricle of 🧠 & on the floor of 4th ventricle & processes extending deep into the hypothalamus. be responsible for serious reproductive, metabolic, mental health consequences in LC pts ➡️ lead to a delayed increase in the risk of neurodevelopmental & neurodegenerative pathologies in all age groups

“A new type of vaccine… has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis and type 1 diabetes—all without shutting down the rest of the immune system.”

Leveraging the liver!

https://erictopol.substack.com/p/an-exciting-new-approach-to-autoimmune

"The participants in the group that were given MDMA experienced significantly greater reductions in their PTSD symptoms compared with those in the group that were given a placebo, according to the research article."

https://www.nytimes.com/2023/09/14/health/mdma-ptsd-psychedelics.html

"While #malaria infection is still prevalent south of the Sahara and in parts of Oceania, such as Papua New Guinea, prior to the 1880s the disease was also endemic in areas that have no longer sustained transmission, including the United States."

https://asm.org/Articles/2023/September/The-History-of-Malaria-in-the-United-States

'This is a hard essay to read or listen to, and it’s meant to be. Clearly, it was hard to write; watching Ursula in her 80s read her own words aloud, more than a decade after she wrote them, the emotion is palpable'

https://lithub.com/watch-ursula-k-le-guin-on-her-illegal-abortion-in-1950/

'And so a lot of the people who try to romanticize what the Roman Empire was and putting themselves into the Roman Empire imagine themselves being, you know, the senator in the fine toga laying on the side, being hand-fed grapes. Whereas more likely than not, they would have died at the age of 28 because of an undiagnosed kidney stone while they were trying to plow their lands.'

https://www.rollingstone.com/culture/culture-features/men-obsessed-roman-empire-explained-tiktok-1234826340/

'The new rules, which went into effect on Sept. 5, mean as many as 10,800 listings for short-term rentals will likely no longer be available, according to a city estimate from the end of March. City officials say the shift will force property owners to rent those homes to residents instead of visitors, helping to ease the city’s housing shortage.'

https://www.nytimes.com/2023/09/16/nyregion/airbnb-nyc-housing-rentals.html

“António Costa está há quase oito anos no Governo e desde 2015 que disse que queria resolver o problema da habitação, quase 8 anos depois nem sequer acabou com o regime dos 'vistos gold', não tocou no regime de residentes não habituais e promoveu o regime dos nómadas digitais. Fez um convite mundial a especuladores para virem especular sobre a habitação do nosso país e colocou a banca a ganhar dinheiro como nunca ganhou até agora”

https://www.publico.pt/2023/09/16/politica/noticia/habitacao-be-pede-sobressalto-acusa-bce-terrorismo-financeiro-2063579

Surprise!

"One explanation for the resurgence of scientific racism—what the psychologist Andrew S. Winston defines as the use of data to promote the idea of an “enduring racial hierarchy”—is that some very rich people are underwriting it."

https://www.theatlantic.com/ideas/archive/2023/09/richard-hanania-racist-pseudoscience-woke-silicon-valley/675335/