Natural killer #NKcell #reprogramming into mature T cells is actively inhibited by the #NuRD complex and #BCL11B-mediated regulation of #H3K27 acetylation - which also inhibit #OPA1-dependent #mitochondrial fusion in #Tcells
Peng Li and collaborators
https://www.embopress.org/doi/full/10.15252/embj.2023113448
'Richard Estes, ‘M Train on Route to Manhattan Approaches the Williamsburg Bridge’ (1995) © Richard Estes, courtesy Louis K Meisel Gallery'
https://www.ft.com/content/0f7b0a94-029b-4d67-8542-03b4c4762744
Information contained in the fMRI signals recorded when the brain is at rest helps to better interpret how changes in blood flow correlate with neural activity across various regions. https://elifesciences.org/digests/86453/spectral-signatures?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Registration is now open for our 2024 Meeting 'Pre-clinical Modelling of Human #Genetic #Disease and #Therapy', organised by Wendy Bickmore, Luke Boulter, Sara Brown, Pleasantine Mill, Liz Patton and Owen Sansom
This should be a fantastic meeting in beautiful Edinburgh, already with a phenomenal line up of speakers!
Apply at https://biologists.com/meetings/dmmgenetics2024
#dmmgenetics
Madalena (right) and Audrey II (she gets bigger.
#Theater #SetDesign #HandMade #ArtGallery #TheaterArts #artmastodon
After moving to the neuromatch.social instance, it is time for a new introduction!
I am a biologist and a neuroscientist. I got a PhD in systems ##neuroscience in the Portugues lab. I have been working with larval zebrafish, where we described a mesmerising circuit encoding heading direction (https://doi.org/10.1101/2022.04.27.489672). I recently moved to the lab of Giuliano Iurilli at IIT (Italy) to follow up in mice my interest in subcortical circuits for naturalistic behavior. I'm a fan of #openscience, #Python, #DIY setups crackpot theories and unconventional paradigms. Sometimes I rant about journals, but I mostly revel in cool (neuro)science!
"The Cell Biology Division of the MRC Laboratory of Molecular Biology (LMB), a research institute within UK Research and Innovation (UKRI), invites applications for a tenure-track Group Leader position."
Assistant Professorship tenure track in Plant Diversity and Macroevolution
University of Zurich
The Faculty of Science at the University of Zurich (UZH) invites applications for the Assistant Professorship tenure track in Plant Diversity a
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-zurich-27778-assistant-professors...
https://jobrxiv.org/job/university-of-zurich-27778-assistant-professorship-tenure-track-in-plant-diversity-and-macroevolution/?feed_id=59937
To migrate efficiently, neutrophils must polarize their cytoskeletal regulators along a single axis of motion. @JasonPTown & @OWeinerLab use spatially-defined #optogenetic control of a leading edge organizer to explore how #neutrophil-like cells balance “decisiveness” (needed to polarize in one direction) with flexibility (to respond to new cues) #PLOSBiology https://plos.io/3ZAldnx
Brazil’s Supreme Court upholds Indigenous rights to reclaim land.
The ruling puts up additional road blocks for mining, logging and cattle industries.
#Climate #ClimateChange #ClimateCrisis
https://grist.org/global-indigenous-affairs-desk/brazils-supreme-court-upholds-indigenous-rights-to-reclaim-land/
Obituary for Jeffrey Pollard at Nature Cancer
"His landmark discovery in 2001 on the tumor-promoting role of macrophages in breast cancer propelled the cancer research field into studying the pro-tumoral roles of the immune compartment."
@jocelyn_etienne @Rxiv_cytoskeleton I guess one solution is to follow the bot, add it to a list, hide the list from your home feed (now possible in 4.2). At least that way the bot traffic is away from your timeline. There needs to be a way to filter the list for actin though. Don't know if that is possible.
One possibility is to support a #Mastodon feature that would allow #unlisted posts to be present in #hashtag feeds, see https://github.com/mastodon/mastodon/issues/23038
For the time being, I see no real solution if you want e.g. to know about new #actin papers but can't parse by yourself all of @Rxiv_cytoskeleton posts...
but we can discuss this, if you have ideas.
'Un estudio publicado recientemente en la revista BMJ Oncology calcula que la incidencia mundial de tumores entre menores de 50 años ha aumentado un 79% en tres décadas. '
'Here, 273 individuals with or without LC were enrolled in a cross-sectional study that included multi-dimensional immune phenotyping and unbiased machine learning methods to identify biological features associated with LC.'
Are you interested in the #cytoskeleton ...?
#actin, #actomyosin, #myosin, #microtubule, #kinesin, #intermediatefilament, #vimentin, #keratin, #desmin, #GFAP, #peripherin, #syncoilin, #internexin, #neurofilament, #synemin, #syncoilin, #lamin
are hashtags used by @Rxiv_cytoskeleton bot.
Unfortunately, if you search / follow one of these hashtags, most of the posts from this bot will be invisible because a recent policy makes them "unlisted", see https://botsin.space/@muffinista/110378654504428500
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"É para já um projecto-piloto, mas a correr bem poderá vir a ser uma solução para mitigar os efeitos da falta de água na agricultura, em concreto na viticultura, e tornar mais eficiente o uso de um bem tão escasso e precioso."
'These episodes made me experience first-hand a phenomenon that I was becoming increasingly familiar with: the vanishing of confidence in science. It seems almost a paradox: as our societies become more and more dependent on advanced technology based on scientific discoveries, people are becoming more and more suspicious of scientists.'
'Similarly, the poorest communes have generally voted much more for the left, especially in cities. That remains true to the present day. The (often intentional) confusion comes from the fact that commentators tend to associate the working classes only with blue-collar manufacturing workers, forgetting that the average wage of supermarket cashiers, restaurant staff, cleaners, care workers and other service industry employees has fallen below that of manufacturing workers for several decades now.'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com