Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Please dont write sentences like this. 'An Italian university' has a name, just like Harvard.

"Dr. Gino was something of an academic late bloomer. After growing up in Tione di Trento, a small town in Italy, she earned a Ph.D. in economics and management from an Italian university in 2004, then did a postdoctoral fellowship at Harvard Business School."

https://www.nytimes.com/2023/09/30/business/the-harvard-professor-and-the-bloggers.html

"Further, when CART cells were treated with IL-4, they developed signs of exhaustion, but when CART cells were treated with an IL-4 monoclonal antibody, they showed improved antitumor efficacy and reduced signs of exhaustion in preclinical models."

#immunology #immunotherapy #CARTCells #Preprint

https://www.biorxiv.org/content/10.1101/2023.09.28.560046v1

🌱I’m going on an adventure, to find the fertilizer🌱

Check out Margot Smit's first post for the "#NewPI diaries" series on the Node:

https://thenode.biologists.com/im-going-on-an-adventure/careers/

(Today is also Margot's first day as a group leader at The Center for Plant Molecular Biology (ZMBP) at University of Tübingen!)

Many of us are alive thanks to the mRNA COVID vaccine developed by today's Nobel Prize winners and many many many others. Here's a short thread of news from today, plus a Q&A with Katalin Karikó and a Scientific American article by Drew Weissman. https://www.scientificamerican.com/article/nobel-prize-medicine-2023-mrna-vaccine-tech/ #nobelprize

'However, as Keller would often emphasize later on, this approach did not mean that McClintock was pursuing science in a distinctively feminine way, either. Instead, as Horning notes, Keller’s aim, stated in “Reflections on Gender and Science,” was the “reclamation, from within science, of science as a human instead of a masculine project.”

https://news.mit.edu/2023/professor-emerita-evelyn-fox-keller-dies-0925

Researchers use historic remnants like antlers, shells, teeth and pollen to learn how natural communities once worked. The clues serve as guides for restoration.

Read more:
🔬 “Conservation paleobiology: Eyeing the past to restore today’s ecosystems,” @KnowableMag
https://arevie.ws/ConservationPaleobio
🔬 “Conservation Paleobiology: Leveraging Knowledge of the Past to Inform Conservation and Restoration,” Annual Review of Earth and Planetary Sciences
https://arevie.ws/Paleobio_EA43

#KnowableMagazine

What is this beautiful neural phenomenon? Cortical spreading depolarizations, some of the brain's tallest waves, are thought to play a role in many things ranging from migraines to seizures.

Learn more about these beautiful and mysterious neural waves in this weeks post, "Catching the Brain's Tallest Waves" by Sophie Liebergall.

https://pennneuroknow.com/2023/09/26/catching-the-brains-tallest-waves/

Image taken by Sophie Liebergall and Zach Rosenthal at the University of Pennsylvania

#sciComm #neuroscience #brain #brainWaves

#OpenCell: A $50 #OpenSource 3-in-1 device for #DNA #extraction:

-combines bead #homogenizer, #microcentrifuge & vortex #mixer
-RPM measurement
-programmable timers
-battery operation
-optional speed control

https://doi.org/10.1101/2023.09.18.558349
#DIYbio #lab #instruments #FrugalScience

Not good. My olive harvest this year will be zero. I mean nothing. Not one olive on the trees. I presume it was down to the extremely hot, extremely long summer. Our fears are that this will be the new normal - science says our fears are justified.

Climate change is hitting our food production. Today.

I expect olive oil to hit €20 per litre in 🇪🇸. 2 years ago it was €4.

#climatechange #oliveoil

https://www.theguardian.com/world/2023/sep/28/europes-local-olive-oil-supply-runs-almost-dry-after-summer-of-extreme-weather?s=09

Excited to be in Geneva & Switzerland 1st time for the @GlobalGenMed meeting. Looking forward to connecting with colleagues & discussing how we can work collaboratively & equitably to enable implementation of #GenomicMedicine #PrecisionHealth in Latin America and other LMICs.

📢 APPLY NOW! 📢
✍️if you want to exchange #openscience experiences and best practices, learn from peers, participate in unconference style teams, engage in thought-provoking discussions and benefit from coaching, in a week in serene surroundings! For more details 👇 www.openscienceretreat.eu

Research from Juma Ward and Paul Martin reveals that microclots and the associated inflammatory response trigger enhanced cancer cell extravasation.
Highlight: https://journals.biologists.com/jcs/article/136/18/e136_e1802/330690/Platelets-and-immune-cells-are-accomplices-in
Article: https://journals.biologists.com/jcs/article/136/18/jcs261225/329658/Live-imaging-studies-reveal-how-microclots-and-the

This article is available under our Read & Publish Open Access initiative.
Researchers can find out about the wide range of benefits, read what researchers are saying and view a list of participating institutions at https://www.biologists.com/library-hub/read-publish/researchers/
#OpenAccess #ReadandPublish

The Netherlands halted extraction from Europe's biggest gas field on Sunday, which was resulting in earthquakes that have shaken local residents for decades and threaten to persist.

Although gas extraction from the field has been almost cut to zero over the last few years, the government kept the site operational due to the global energy uncertainties prompted largely by Russia's invasion of Ukraine in February 2022.

https://www.france24.com/en/europe/20231001-netherlands-shuts-europe-s-biggest-gas-field-over-quake-concerns

#Netherlands #Groningen #Gas #Energy #Earthquakes

For today's #MosaicMonday an early 4th century AD mosaic, discovered in the basilica of Aquileia, depicting the fight between a rooster and a turtle, commonly interpreted as the representation of light/good (rooster) and darkness/evil (turtle).

#LateAntiquity
#RomanArchaeology

[da capo] The Magasanik Paradox
by Elio
The journal Nature published a study of the most 100 most cited scientific papers that provides food for thought to the working stiffs (I used to be one). First of all, I find it quite natural for any researcher to keep an eye on how often his or her work is cited.
Read more > https://tinyurl.com/svwf8jch
#microbiology

Hybridizing #species are usually maintained by genome-wide selection against #introgression or by selection on a few “genomic islands.” @yanivbrandvain & Shelley Sianta explore #PLOSBiology study which finds a new pattern – 60 SNPs across the #genome differentiate #Penstemon species with different #pollinators. Paper: https://plos.io/3LGHkD9 Primer: https://plos.io/3RHSF9L