Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Here is a new thread for friends of #PaperHistory, #BookHistory, and the #histodons community.
@histodons

On the painting with the title "The Alchemist" from the Flemish Mattheus van Helmont, circa mid seventeenth century, are many uses and abuses of #earlymodern paper products reflected in the details. I will address 7 of these paper issues in the thread. Bonus for #Alchemy friends: a large écorché figure, a distillation apparatus over a fire, and metal working assistants.
Enjoy.

1/x

How a #BigPharma Company Stalled a Potentially Lifesaving #Vaccine in Pursuit of Bigger Profits
==

A vaccine against #tuberculosis, the world’s deadliest infectious disease, has never been closer to reality, with the potential to save millions of lives.

But its development slowed after its corporate owner #GSK focused on more profitable vaccines.

#Health #TB #PublicHealth #News

https://www.propublica.org/article/how-big-pharma-company-stalled-tuberculosis-vaccine-to-pursue-bigger-profits?utm_medium=social&utm_source=mastodon&utm_campaign=mastodon-post

The past, present and future of science publishing.

Long read from me giving the history (not always told well), details of how journals actually work (useful for young scientists and to clarify for old hands), and discussion of how the future could look in a post-preprint world (spoiler: academia could get this wrong).

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002234

Let's hope he follows through:

'Tax breaks for foreign residents in Portugal are “no longer justified”, the prime minister, Antonio Costa, has declared, promising to close the scheme for new applicants in 2024 after it stoked housing prices in one of western Europe’s poorest nations.'

https://www.theguardian.com/world/2023/oct/03/portugal-to-scrap-unjust-tax-breaks-for-foreign-residents

Issue 18 is complete!

On the cover: CRISPR knockout of Wnt receptor frizzled2 leads to fragmented (non-cell-autonomous) disruptions in wing marginal patterns in the Painted Lady butterfly as a result of mosaic loss of function of WntA. See Hanly et al.:
https://journals.biologists.com/dev/article/150/18/dev201868/329659/Frizzled2-receives-WntA-signaling-during-butterfly

Also in Issue 18:
▪4 Research Highlights on Rasa1, Twist1, Vestigial & WntA
▪Interviews with PI Fellows
▪Behind the paper interview
▪Gastric epithelial stem cells Review

https://journals.biologists.com/dev/issue/150/18

Postdoctoral Research Associate-Pharmacy & Pharmaceutical Sciences

St. Jude Children's Research Hospital

See the full job description on jobRxiv: https://jobrxiv.org/job/postdoctoral-research-associate-pharmacy-pharmaceutical-sciences/?feed_id=60682

#ScienceJobs #hiring #research
Memphis #UnitedStatesUS #PostdoctoralFellow #ResearchAssistant #ResearchTechnician #Researcher
https://jobrxiv.org/job/postdoctoral-research-associate-pharmacy-pharmaceutical-sciences/?feed_id=60682

Katalin Karikó won a Nobel Prize for her work on the COVID mRNA vaccines. Yet just 10 years earlier, UPenn kicked her out of academia.

"They told me that they’d had a meeting and concluded that I was not of faculty quality. When I told them I was leaving, they laughed at me and said, ‘BioNTech doesn’t even have a website.'"

https://www.wired.co.uk/article/mrna-coronavirus-vaccine-pfizer-biontech

The Pythagorean Theorem is at least a thousand years older than Pythagoras. Turns out Babylonians knew some pretty advanced math.

https://www.iflscience.com/pythagorean-theorem-found-on-clay-tablet-1000-years-older-than-pythagoras-70934

On #EMmonday we’re highlighting slit assembly in Drosophila nephrocytes. Marta Carrasco-Rando, Mar Ruiz-Gómez and colleagues @CBMSO_CSIC_UAM discover that an acytokinetic cell division breaks membrane symmetry during slit diaphragm assembly.
📖 @Dev_journal: https://journals.biologists.com/dev/article/150/18/dev201708/328448/An-acytokinetic-cell-division-creates-PIP2
#OpenAccess

"After realising that many notable women working in science, technology, engineering and maths (Stem) and others from minority backgrounds did not have Wikipedia pages, though they were deserving of them, she decided to start them herself, one every day. Each one takes “a few hours” to write, she says. It’s a task, she confesses, that she somehow completes while simultaneously watching real estate shows on Netflix in the evening. To date, she has contributed more than 2,000 entries."

https://www.theguardian.com/science/2023/oct/01/why-are-they-not-on-wikipedia-dr-jess-wades-mission-for-recognition-for-unsung-scientists?CMP=Share_iOSApp_Other

A CRISPR-based strategy to promote endogenous fetal hemoglobin re-expression to treat sickle cell disease: my latest Nature Medicine column.

#SickleCell #GeneTherapy #Crispr

https://www.nature.com/articles/d41591-023-00088-6

A Galaxy of informatics resources for MS-based proteomics https://www.tandfonline.com/doi/abs/10.1080/14789450.2023.2265062

---
#proteomics #prot-paper

Swedish medical physicist and "Father of Radiation Protection" Rolf Maximilian Sievert died #OTD in 1966.

He played a pioneering role in the measurement of doses of radiation especially in its use in the diagnosis and treatment of cancer. In later years, he focused his research on the biological effects of repeated exposure to low doses of radiation. He was a founder of the International X-ray and Radium Protection Committee (later became ICRP) in 1928. He also chaired the UNSCEAR.

#science

Shift Happens is a beautifully designed history of how keyboards got this way https://arstechnica.com/?p=1972356

#intro #présentation

Je suis chercheuse en #Economie du #ChangementClimatique au centre-cired.fr. Je travaille sur les impacts du changement climatique et sur les trajectoires et politiques d'atténuation du CC, en me concentrant souvent sur les liens avec les #inégalités.

J'ai participé au rapport du #GIEC sur l'atténuation, et je suis membre du Haut conseil pour le climat.

Je parlerai ici de #recherche, #enseignement, #interdisciplinarité, #transformations pour notre avenir commun.