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Something I internalized living in a non-English country (with fantastic colleagues).
Even reading a paper is an extra mental effort, as it's using the "translate" part of the brain for an ESL speaker.

Now when I write, I try to remember the majority of my audience are ESL - avoid faff, read easy.

#AcademicChatter #PeerReview #ScientificPublishing

See: qoto.org/@cyrilpedia/111238064

The Book Wheel was an invention from the 16th century for people that needed multiple tabs open before browsers were invented.

"Coincidently, the DNAm changes observed in aging, cancer, and proliferation share some notable patterns. In general, they tend to be characterized by gains in methylation at promoters—especially those marked by polycomb group (PcG) factor targets—and loss of methylation in intergenic regions and repetitive elements"

science.org/doi/10.1126/sciadv

I missed this, but @openDemocracy notes that while #SuellaBraverman & her unsavoury band of #migrants hating #Tories were decrying the inability of some migrants to speak English, a programme the govt. was going to launch that would have targeted aid to help migrants learn to speak English had been dropped...

words fail me..... (for once)

opendemocracy.net/en/esol-nati

"Resumo: o poder do Hamas nasce da ocupação. Mas também do falhanço da AP perante o seu povo; do falhanço contínuo dos regimes árabes perante os palestinianos; e do falhanço internacional perante o mais longo e obsceno statu quo de um povo ocupado há décadas, apesar das resoluções da ONU. Que, sendo a máquina que permite a milhões de palestinianos viver desde 1949, é também, por isso, tragicamente, a que viabiliza o status quo."

publico.pt/2023/10/13/mundo/op

As von der Leyen visits Israel, is the European Commission overstretching its powers?

Since the horrific attack by Hamas on innocent Israeli civilians last weekend, European Commission president Ursula von der Leyen has expressed unambiguous support for Israel, without member states’ mandate, and apparently regardless of how Israel chooses to respond.

irishtimes.com/world/middle-ea

#EU #EuropeanCommission #VonDerLeyen #Israel #Palestine #Gaza

"Although a Nature survey suggests that scientists who use LLMs regularly are still in the minority, many expect that generative AI tools will become regular assistants for writing manuscripts, peer-review reports and grant applications."

nature.com/articles/d41586-023

Not sure what those who advocate for the use of ChatGPT in scientific writing have in mind. It is the very act of writing that helps us think about the connections and implications of our results, identify gaps, and devise further experiments and controls.

Any science project that can be written up by a bot from tables of results and associated literature isn’t the kind of science that I’d want to do to begin with.

Can’t imagine completing a manuscript not knowing what comes next, because the writing was done automatically instead of me putting extensive thought into it.

And why would anyone bother to read it if the authors couldn’t be bothered to write it. Might as well put up the tables and figures into an archive online, stamp a DOI on it, and move on.

#ScientificPublishing #science #ChatGPT

"Here are the FDA briefing documents for the meeting being held today (Thursday, October 5). If you read Amgen’s press releases from the last two or three months and then read this stuff, you will feel as if you have stepped through a portal into another dimension."

science.org/content/blog-post/

🫘 🧪 Renal biomarkers can be used to define/identify of subclinical acute kidney injury, frequent & severe condition with prognosis equivalent to #AKI, as defined by KDIGO criteria based on ⬆️ serum creatinine: ancillary analysis of FROG-ICU study 🐸
Results free to read on @ICM #FOAMcc
🔓 rdcu.be/dlsf9
⬇️ Below visual abstract

@cyrilpedia I'm a supporter of FDA generally ... its role is vital.

Given its known mutagenic mechanism of action and the availability of a safer and efficacious alternative (Paxlovid)... it's a mystery to me why this drug was authorized by #FDA .

"The emergence of variants of concern complicated the relatively simple relationship between attaining protection after immunization with vaccines based on the ancestral SARS-CoV-2 strain (5). It is critical to disentangle the issue of waning immunity from immune escape by emerging variants."

science.org/doi/10.1126/scienc

"However, it remains unknown how JH3 degradation results in neurodevelopmental outcomes that translate into distinct worker behaviors, how this is accomplished at the molecular and cellular level, and whether differential regulation of JH3 levels early in life is sufficient to accomplish lifelong Major-Minor division of labor in C. floridanus."

cell.com/cell/fulltext/S0092-8

"But for all that progress, a disparity is emerging: Women between the ages of 35 and 54 are being diagnosed with lung cancer at higher rates than men in that same age group, according to a report published Thursday by researchers at the American Cancer Society. The disparity is small — one or two more cases among every 100,000 women in that age range than among men — but it is significant enough that researchers want to know more."

nytimes.com/2023/10/12/well/li

"Highlighting the role of repeated immune responses, our results confirm the role of REL in the germinal center reaction and provide evidence supporting the fact that genetic deregulation of c-Rel expression is most likely a primary event in the aggressive transformation of GC B-cells."

biorxiv.org/content/10.1101/20

"The knob interaction with SARS-CoV-2 spike was revealed by electron microscopy, X-ray crystallography, NMR spectroscopy, and mass spectrometry and established ultralong CDR H3-derived knobs as the smallest known recombinant independent antigen-binding fragment"

pnas.org/doi/10.1073/pnas.2303

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