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Individual rare diseases are... rare. But taken together, they affect a significant fraction of the population. We need to develop a sustainable economic model for gene therapy.

"As a result, while the number of people eligible for any single gene therapy might be small, the total number of people eligible across all of them could soon be significant. Annual spending on gene therapies could increase from $5.15 billion 2020 to $25.3 billion in 2026."

bloomberg.com/opinion/features

‼️Deadlines for ERC Starting Grants and Synergy Grants calls are extended.
nitter.cz/search?q=%23ERCStG
: from 24 Oct to 7 Nov 2023
nitter.cz/search?q=%23ERCSyG
: from 8 to 15 Nov 2023
The reason for the changes are disruptions caused by the fallout of Hamas’ terrorist attacks across Israel.
erc.europa.eu/news-events/news

🐦🔗: nitter.cz/ERC_Research/status/

[2023-10-18 08:27 UTC]

"What’s most important is that these models ensure equitable access to these treatments for any eligible patient. The tens of thousands of people with sickle cell should all have the same opportunity as Carter: to wake up one day and feel what it’s like to not be in pain. Equitable access is also what matters for the future of the technological revolution brewing in medicine. After all, what good are miracle cures if only the few can get them?"

bloomberg.com/opinion/features

Can't stand the heat? How nutritional status modulates #thermosensation: behavioral & live brain imaging studies reveal why food-sated #FruitFlies prefer to stay at relatively higher temperatures compared to hungry flies #insulin #PLOSBiology plos.io/400hmjQ pic.twitter.com/8eRF13QtHg

.@alanmcn1 &co use a mouse colonization model to show that a #MultiDrugResistant (MDR) strain of #Ecoli can displace commensal strains from the gut; selection pressures occurring in the #MDR strain result in streamlining of their metabolism #PLOSBiology plos.io/45AqQUf pic.twitter.com/AYgAda9BaK

From Filipe França on the bird site:

🚨Black heritage PhD studentship, please boost🚨

How do forest disturbances affect tropical insect food webs?
🌴🌳🪲🐝🌳🌴👩🏾‍🔬🧑🏿‍🔬🧑🏾‍🎓👩🏿‍🎓

Interested in tackling this question? Check bit.ly/3QkdvLu

As an effort to tackle the under-representation of black people in PG research & academia, Bristol Uni launched a number of PGR research scholarships open exclusively to UK-domiciled black or black-mixed PhD applicants.

Orig. tweet here: twitter.com/FilipeEco/status/1

'Le Carré’s interview was filmed in 2019. It would be his last. He died in December 2020. And while the circumstances were sudden — a fall in his home — the writer had been 88 when sitting down with Morris. It is not an age when one is unaware that time is finite. Now, The Pigeon Tunnel shares with The Fog of War (after which Robert McNamara died in 2009) a sense of legacy.

“You make me sound like the Grim Reaper,” Morris says. Not quite, I say. But the Grim Reaper’s documentary maker? He pauses. I worry I’ve offended him. “No, I like it!”'

ft.com/content/8a048174-e10a-4

'Los últimos datos de la OMS Europa, con 33 países, y la Iniciativa Europea de Vigilancia de la Obesidad Infantil (COSI por sus siglas en inglés), mostraron que el 29% de los niños de siete a nueve años presentaron sobrepeso y obesidad.'

elpais.com/salud-y-bienestar/2

This would be so amazing IF the government took heed as would truly support economic growth and be better for climate with benefits for all in costs saved too but will they support it? I fear the populist policies embraced by Rishi may not. theguardian.com/business/2023/

I just can‘t get enough … still adjusting conditions and protocols.

Really astonishing what cells can do.

#biology #nephrology #kidney #stemcells #iPSC

Did ancient Egyptians know meteorites came from space?

Smithsonian Magazine reports: "Hieroglyphic texts suggest they understood the rocks, which contained valuable iron, did not originate on Earth."

flip.it/P.yBu8

#Egypt #AncientEgypt #Space #Meteorites #History

Rich people are under the mistaken impression that they have valuable thoughts.

I have no issues whatsoever with people wanting to be on Bluesky; in fact, if it hastens the demise of Twitter/X which now seems beyond repair, I’m personally all for it- as far as politics, cat pictures, thoughts on the world in general etc are concerned

but I don’t understand how moving *science discourse* to a for profit, invite only, platform is in any way compatible with the goals of open science and science reform.

am I missing something?

The Medieval Sect That Inspired the Video Game 'Assassin's Creed': From Marco Polo to the Assassin’s Creed video game franchise, the Nizari Ismailis have inspired fascination and fanciful stories. But who were these bold assassins really? smithsonianmag.com/history/the

During the next Community Call, we will hear from @lonnibesancon, who has conducted multiple meta-research projects and written opinion pieces focussed on unreliable science or fraudulent data.
asapbio.org/event/november-202

In response to Lonni's rigorous and scientific approaches, he has faced lawsuits and attacks from senior scientists.
The talk from Lonni about his experiences will be followed by a longer discussion.

#ECRs #preprint #preprints #research #science #OpenScience

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