"The NLOS that spits out the Transplant Benefit Scores is one of dozens of algorithms in use in healthcare systems around the world. These applied statistical systems are used by physicians and hospitals to aid decisions such as who receives heart surgery and organ transplantation, which patients are at the highest risk of surgical complications, and in diagnosing cancers and brain injury. The intent behind predictive algorithms, like the NLOS, is to make consequential decisions fairer."
https://www.ft.com/content/5125c83a-b82b-40c5-8b35-99579e087951
The superior, durable immune response for a mucosal (nasal or nebulizer) Covid booster compared with bivalent shot in non-human primates vs XBB.1.16 variant infections
http://biorxiv.org/cgi/content/short/2023.11.06.565765
Fruit bowl with bat, glazed stoneware by @hunchbacksociety
#Ceramics #stoneware #pottery #Handmade #Art #artgallery #artmastodon
Posting for those who may need this:
ProPublica has created a tool to help consumers fight denied health insurance claims: https://projects.propublica.org/claimfile/
A complete mass spectrometry-based immunopeptidomics pipeline for neoantigen identification and validation https://www.researchsquare.com/article/rs-3520814/v1
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#proteomics #prot-preprint
"Then, 20-odd years ago, some researchers began to ask a heretical question: is the brain really so isolated? The answer, according to a growing body of evidence, is no — and has important implications for both science and health care."
"Follicle cells triggered by hair movements release the neurotransmitters histamine and serotonin, chemical messengers linked to biological phenomena as varied as inflammation, muscle contraction and mood changes."
https://www.nytimes.com/2023/11/08/science/hair-follicle-neuron-touch.html
'Varias universidades árabes pagan hasta 70.000 euros anuales por cabeza a reputados científicos extranjeros para que mientan y declaren en una base de datos que su lugar de trabajo principal está en Arabia Saudí.'
"SARS-CoV-2 infection is milder in children, but the underlying mechanisms are not fully understood. This study finds increased interactions between immune and epithelial cells in children's noses, priming the epithelium for stronger interferon responses upon infection."
Magalhães et al @emboreports
A while back we asked you, the Node community, to vote for your favourite artwork from @BSDB #DevBio_Art exhibition — the results are now in!
Have a look at the People's and Judges' choices of #microscopy images and #SciArt work:
https://thenode.biologists.com/peoples-choice-and-judges-choice-from-the-bsdb-the-node-virtual-art-exhibition/
The exhibition is still open until the end of November! Have a stroll around:
🔬Scientific images
https://artspaces.kunstmatrix.com/node/12245599
🖼#SciArt and 'Art by scientists'
https://artspaces.kunstmatrix.com/node/12245684
🦞🐬🐢🐤Historic embryo zoo
https://artspaces.kunstmatrix.com/node/12186775
Austrian Actress Hedy Lamarr (Hedwig Eva Maria Kiesler) was born #OTD in 1914 (not 1913).
At the beginning of World War II, she and avant-garde composer George Antheil developed a radio guidance system for Allied torpedoes that used spread spectrum and frequency hopping technology to defeat the threat of jamming by the Axis powers. Though it was never used in wartime, this device is a component of present-day satellite and cellular phone technology. via @wikipedia
Fast alignment of mass spectra in large proteomics datasets, capturing dissimilarities arising from multiple complex modifications of peptides - BMC Bioinformatics https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05555-y
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#proteomics #prot-paper
"A team of researchers backed by Alzheimer’s Research UK and the Alzheimer’s Society have launched a £5m project to trial simple blood tests in the NHS, with the hope of speeding up diagnosis and reaching more people. They aim to be able to determine whether someone has the disease using a single drop of blood."
The immune landscape of murine skeletal muscle regeneration and aging
"...challenge established notions on immune regulation of skeletal muscle regeneration, providing a new set of potential targets to improve skeletal muscle health and regenerative capacity in aging.".
https://www.biorxiv.org/content/10.1101/2023.11.07.565995v1.full.pdf+html
"What we are focused on now is the expansion of biological specificity. Modern quantitative biology has great instrumentation to measure how things work physiologically, but that needs really specific readouts; if the reagent that you are using is not specific enough, then your assay probably won't be very good."
"Tuberculosis, which is preventable and curable, has reclaimed the title of the world’s leading infectious disease killer, after being supplanted from its long reign by Covid-19. But worldwide, 40 percent of people who are living with TB are untreated and undiagnosed, according to the World Health Organization."
https://www.nytimes.com/2023/11/06/health/tuberculosis-tb-treatment-vaccine-diagnosis.html
"The Covid inquiry has shown us that inside No 10 there was a combination of squabbles, chaos and incompetence best described as an absurdist tragedy. The obvious takeaway is, “don’t elect someone like Boris Johnson”"
‘The analysis estimates that 1.5–2% of all scientific papers published in 2022 closely resemble paper-mill works. Among biology and medicine papers, the rate rises to 3%."
Thanks to LS4FUTURE Associated Laboratory for the invitation to speak at Career Day 2023 - and to hear the other panelists's stories. As a side note, it was odd to learn from postdocs at the speed-dating portion of the afternoon that Portugal's government had fallen (as if they needed *more* uncertainty).
(Photo by Andreia Freitas/IBET)
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com