"Animals lacking microglia show increased metastasis, decreased survival and reduced natural killer and T cell responses, showing that microglia are critical to promote anti-tumour immunity to suppress breast cancer brain metastasis."
#Immunology #TumorImmunology #Microglia
"We asked students several questions about the scheduling structure, frequency, and helpfulness of their individual meetings with their advisors. Frequent meetings were a positive predictor of nearly every aspect of well-being and productivity measured in the survey."
Do you know we have a subject collection with a focus on techniques and resources in #DevBio?
Check out this collection showcasing some of our recent Techniques and Resources papers and review-based articles discussing newly developed tools & approaches in the field:
https://journals.biologists.com/dev/collection/9852/Focus-on-techniques-and-resources
#IDMastodon No significant differences in #IgG #RBD #antibody concentration after #covid19vaccination were found between older adults who had been BCG-vaccinated in the year preceding #COVID19-specific vaccination compared with those who received a placebo vaccine @iscience_cp
https://www.cell.com/iscience/fulltext/S2589-0042(23)02139-9?rss=yes&utm_source=dlvr.it&utm_medium=twitter
In their Review, Rachel Thayer & Nipam Patel discuss structural colors in #butterflies, how they are produced, the range of colors & their phylogenetic distribution, while also giving testable hypotheses for future studies.
https://journals.biologists.com/jeb/article/226/21/jeb245940/334657
"Although type 1 conventional dendritic cells (cDC1s) were not required for initial priming of CD4+ T cells, cDC1s were required for CD4+ T cell expansion and gut homing. cDC1s were also a major source of IL-12 that was not required for priming but promoted full differentiation of CD4+ T cells and local production of IFN-γ. Together, these studies reveal distinct roles for cDC1s in shaping CD4+ T cell responses to enteric infection: first to drive early expansion in the mesLN and second to drive effector responses in the gut."
#InfectionImmunity #Immunology #MucosalImmunology #parasitology #Preprint
I am actively recruiting students for my lab at UMass Dartmouth!
Are you interested in a project on actin, amoebae, cell migration, and/or pathogenesis? Send me an email & apply to the Integrative Biology PhD program by Jan 15!
Please RT
More info: https://katrinavelle.wixsite.com/science
Meanwhile, in Portugal, no trains & more airports:
"The Socialist Workers' Party of Prime Minister Pedro Sánchez has signed a coalition deal with the far-left Sumar party that includes some 230 policy promises covering the next four years — including a pledge to limit short flights within the country."
https://www.politico.eu/article/spain-aims-to-say-adios-to-short-haul-flights/
"Combining molecular dating, phylogeography, and comparative genomic analyses of a large collection of isolates, we find that several pathogenic lineages of S. suis emerged in the 19th and 20th centuries, during an early period of growth in pig farming. These lineages have since spread between countries and continents, mirroring trade in live pigs."
#InfectiousDisease #zoonosis
Stereotyped goal-directed activity patterns in the insular cortex https://www.biorxiv.org/content/10.1101/2023.11.13.566809v1?med=mas
The formation of a new coalition government in Spain portends big changes for the country's short-haul flights.
The coalition deal includes some 230 policy promises covering the next four years — including a pledge to limit short flights within the country.
The idea is similar to a program in France, and would scrap domestic flights where there is a rail alternative that takes less than two-and-a-half hours
https://www.politico.eu/article/spain-aims-to-say-adios-to-short-haul-flights/
#Spain #ShortHaul #Flights #Aviation #HighSpeedRail #Politics
“Be #sustainable!”
@eosclife assembles recommendations and resources for concrete implementation of #FAIR principles in #lifescience research
https://www.embopress.org/doi/full/10.15252/embj.2023115008
German astronomer and mathematician Johannes Kepler died #OTD in 1630. He is a key figure in the 17th-century Scientific Revolution, and his books Astronomia nova, Harmonice Mundi, and Epitome Astronomiae Copernicanae, influencing among others Isaac Newton, providing one of the foundations for his theory of universal gravitation. The variety & impact of his work made Kepler one of the founders and fathers of modern astronomy, the scientific method, natural and modern science.
Our group has several 3y+ #postdoc openings at the Centre for Organismal Studies at Heidelberg University. Come and join us in Heidelberg to study eye evolution, #cilia, #behaviour by #connetomics #vEM etc. #neuroscience #Evolution #job #science
https://adb.zuv.uni-heidelberg.de/info/INFO_FDB$.startup?MODUL=LS&M1=1&M2=0&M3=0&PRO=34018
"It is very probable that the great stratum called the Milky Way is that in which the sun is placed, though perhaps not in the very centre of its thickness. "
Sir William Herschel: His Life and Works (1880)
as quoted by Edward Singleton Holden via @wikipedia
Books about William Herschel at PG
https://www.gutenberg.org/ebooks/52923
https://www.gutenberg.org/ebooks/29031
'A new venture, led by the founder of a biotech group that was sold to Sanofi for up to $1.45bn in 2021, has won £48mn in funding for research into cancer treatments using machine learning and genetically engineered mouse technology.'
https://www.ft.com/content/73c41613-5fc7-499b-9858-2eeb456014bb
"The prints are very small, some are roughly the size of a stamp, & are at times watercoloured." @madparreira
Mini-etchings inspired by Seghers, Rembrandt & Bruegel the Younger/loosely inspired by 17th century Dutch landscape paintings.
#Print #Printmaking #Etching #Handmade #Art #ArtGallery #artmastodon
"Chronic viral infections are known to accelerate immune aging and to induce immune senescence (21, 22). We have shown that among 206 viruses with human tropism, only CMV seropositivity was associated with senescence of CD8+ T cells in patients with aNSCLC."
#Immunology #TumorImmunology #Immunotherapy
It was an incredible privilege to attend this workshop on cancer immunotherapy organized by Tasuku Honjo & Antonio Coutinho and hosted by the Fondation des Treilles in Provence.
I put together a brief meeting report for the foundation, you can read it here 👇
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com