Fellow Mstdn.Science users - We're living through tough times right now, in so many ways. Not everyone agrees with each other, not everyone can see eye-to-eye.
While we do not tolerate abuse, slurs, or hate speech - someone disagreeing with you (even in a heated way) is not a bannable offense. We are grateful for everyone who keeps civil discourse on tough topics. Remember, you can always personally block those you don't want to engage with.
Thank you for being part of our instance! ♥
"How exactly the drug prevents major cardiac events isn’t fully understood. Some of the effects can likely be chalked up to weight loss itself, which is associated with improvements in metrics that influence heart health, such as blood pressure, Yang said. But mechanisms independent of weight loss may also be at work. In the trial, lower rates of cardiovascular events began showing up before participants lost weight. One explanation is the drug’s impact on inflammation, which is associated with heart disease: C-reactive protein, a rough proxy for inflammation, dropped by nearly 40 percent in study participants."
https://www.theatlantic.com/health/archive/2023/11/ozempic-wegovy-obesity-drugs-benefits/676011/
“The current ideas to reduce the number of international students and staff give the wrong signal and will scare international top talent away at a time in which our economy and society as a whole are in desperate need of highly skilled labour forces,” said Robert-Jan Smits, president of the executive board of Eindhoven University of Technology. “We should not make the same mistake as Denmark.”
"Dancer Amandine Albisson performs "Chiroptera" as thousands gather in front of the Palais Garnier Opera House in central Paris to watch the facade of the opera house transformed into a philosophical allegory of Plato's cave, as part of a new project by the French artist JR on November 12, 2023."
Observations of respiratory syncytial virus (RSV) nucleic-acids in wastewater solids across the United States in the 2022-2023 season: Relationships with RSV infection positivity and hospitalization rates https://www.medrxiv.org/content/10.1101/2023.11.16.23298599
Interesting results from the British Academy's experiment of randomizing the awarding of research grants. While all the proposals eligible for funding have passed a high quality threshold random selection of what proposals receives funding increases diversity quite dramatically on several dimensions.
"Our study thus reveals an unsuspected role of histone eviction from insect sperm chromatin: safeguarding the integrity of the male pronucleus during female meiosis."
In this episode we talked with Maria Gambetta from the University of Lausanne about her work on the function of insulators in 3D genome folding. #womeninstem #podcast #epigenetics
Listen here: https://activemotif.com/podcasts-maria-gambetta
"We suggest ‘phenotypic noise’ be used to distinguish non-genetic changes in phenotype that occur independently from the environment. We discuss the conceptual and methodological techniques used to identify these phenomena during cancer evolution."
https://www.sciencedirect.com/science/article/pii/S0962892423002064#f0005
'Na conversa, o jurista confirmou que o território foi sempre uma espécie de cofre para os partidos portugueses e que o dinheiro chegava em malas a Portugal. “Que eu saiba, com excepção do PCP, toda a gente lá foi”, garantiu, admitindo também que Stanley Ho, entre outros, seria uma das fontes de financiamento.'
https://www.publico.pt/2023/11/17/politica/noticia/negocios-china-lacerda-machado-2070533
Finally heard back from that rogue invited speaker? You still have time to submit your symposium proposal for #SMBE24!! Deadline is today (Nov 17)!! SMBE2024.org
"If Zoom meetings leave you feeling like something is missing, know that you’re not alone. According to a new study by researchers at Yale and University College London, staring at someone’s face on a computer screen results in lower levels of brain activity and social arousal than meeting them in person."
Not great. Gantenerumab is a monoclonal antibody against aggregated Aβ:
"Among persons with early Alzheimer’s disease, the use of gantenerumab led to a lower amyloid plaque burden than placebo at 116 weeks but was not associated with slower clinical decline."
#alzheimers
https://www.nejm.org/doi/full/10.1056/NEJMoa2304430?query=featured_home
"According to the V.A., the Million Veteran Program is the largest such database in the world. It includes not only genetic information but also is linked to the department’s electronic medical records and even contains records of diet and environmental exposure."
https://www.nytimes.com/2023/11/15/health/million-veterans-database-va.html
"That doctor had to be talking about Stieve, Hildebrandt says, since “there is no other ‘Nazi experiment’ like this.” It was another link in the chain from Stieve to Mecklenburg to Willke to today’s anti-abortion Republicans."
(article is fm 2013)
"Early results from an innovative new trial in how the British Academy awards its Small Research Grantssuggests that introducing partial randomisation into the selection process could lead to a more ethnically and institutionally diverse cohort of award-holders."
"The bat fossil record also provides significant evolutionary insights, although it is one of the poorest of any mammalian order, with ∼80% of the record estimated to be missing. The world’s oldest known bat fossil consists of a single, 56 mya lower molar from Portugal"
https://www.cell.com/current-biology/fulltext/S0960-9822(23)01289-7
Menu:
- Um truque inovador para reduzir o número de candidaturas a financiamento de projetos de investigação
- Um subterfúgio de secretaria para falsear as taxas de sucesso.
- A falsa regularidade dos concursos para financiamento de projetos.
"(...) in 1986, it eventually led him to #immunology—via an unusual patient. She was the wife of a government minister, a privileged woman who nevertheless had spent years being sent from one expert to another, some of whom said her problem was in her head. Her problem? She itched! Everywhere all over her skin, to the point of scratching her skin bloody. Albert was a young dermatology resident when he was asked to take care of her."
https://www.cell.com/immunity/fulltext/S1074-7613(23)00443-0?dgcid=raven_jbs_etoc_email
"To further promote good science, he worked hard at educating students and postdocs, and he became a wonderful teacher. Eschewing textbooks (because of any author’s inescapable biases), he taught from the primary literature. Students loved his classes, and he won the University of Chicago’s “Llewellyn/Quantrell award for excellence in undergraduate teaching ”, chosen from the entire University as best teacher of the year."
https://www.cell.com/immunity/fulltext/S1074-7613(23)00443-0?dgcid=raven_jbs_etoc_email
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com