Thiago Carvalho @cyrilpedia@social.cleverlibre.org

"These draft pages make it possible to see in detail how Darwin originally composed and revised many of his arguments and expressions. The drafts also contain many sentences that were never published, offering fascinating insights into Darwin's thinking as he composed the book that quite literally changed the world."

http://darwin-online.org.uk/EditorialIntroductions/vanWyhe_Drafts_of_Origin_of_species.html

Chaque année, le massif de Belledonne, qui s’étend entre l’Isère et la Savoie, attire de nombreux pratiquants d’activités récréatives de montagne. En cette saison, la montagne accueille également les troupeaux et leurs bergers, avec lesquels randonneurs...
https://lejournal.cnrs.fr/diaporamas/la-montagne-un-habitat-qui-se-partage?utm_medium=Social&utm_source=Mastodon

"Netanyahu has a salient interest in the war continuing until Donald Trump ousts Biden from the White House. That would help him implement his three “noes” – no acceptance of responsibility, no elections and no Palestinian state."
https://www.haaretz.com/opinion/2023-11-20/ty-article-opinion/.premium/is-it-good-to-die-on-the-altar-of-netanyahus-lifes-work/0000018b-ee64-ddc3-afdb-fe75c6600000

"Tal vez su mayor contribución a la guerra no estuvo en las trincheras, sino en el legado de su testimonio. Una investigación ha calculado que los 2.300 combatientes británicos que lucharon en la guerra de España escribieron y publicaron, entre todos ellos, 730 obras literarias, en su mayoría diarios de guerra."

https://elpais.com/cultura/2023-11-25/ultimo-verso-en-la-trinchera-los-poetas-con-fusil-que-murieron-por-un-ideal.html

Postdoctoral fellow in Bioinformatics/Genomics

Institut Curie

We are hiring a postdoc in bioinformatics to join my lab in Institut Curie and beautiful Paris!
Exciting projects using single-cell omics data

See the full job description on jobRxiv: https://jobrxiv.org/job/institut-curie-27778-postdoctoral-fellow-in-bioinformatics-genomics/?feed_id=66283

#ScienceJobs #hiring #research ...
https://jobrxiv.org/job/institut-curie-27778-postdoctoral-fellow-in-bioinformatics-genomics/?feed_id=66283

Francis Bacon. 2nd Version of Triptych, 1944, 1988.
"'Part man, part beast, these howling creatures first appeared in Three Studies for Figures at the Base of a Crucifixion, which Bacon painted during the Second World War. One critic described that picture as a reflection of ‘the atrocious world into which we have survived’. Bacon identified his distorted figures with the vengeful Greek Furies, while the title places them in the Christian context of the crucifixion.'"
- Tate Gallery label, 2005

Protesters blockaded the world’s largest coal port for 30 hours over the failure of government to act on climate change, preventing more than half a million tonnes of coal from leaving the port of Newcastle.

“Pancakes were being made, tea drunk, #dolphins swam nearby and people watched the sunset and sunrise. Those involved say it was a magical experience.”

- Rising Tide local organiser Alexa Stuart

Protesters spent the night on the water, rostered in two-hour shifts.

#Newcastle #StopCoal #PeoplesBlockade #RisingTide #ClimateChange #NSW #Australia

A scandal of the century is the energy-industrial complex taking over the G.O.P. - the Gas and Oil Party.

This loss of American liberty is exposed in "Climate Denial in American Politics: #ClimateBrawl."

👉 Order now - 25% DISCOUNT 👈

https://routledge.com/Climate-Denial-in-American-Politics-ClimateBrawl/Kutney/p/book/9781032592794

"We demonstrated that a DSB located upstream of CAG repeats induces polymerase theta-mediated end joining, resulting in deletion of the entire CAG tract."

#Preprint

https://www.biorxiv.org/content/10.1101/2023.11.24.568568v1

'As of 2022, no journal published in Latin America appears in lists of the world’s publications with the highest impact factors; these journals are more vulnerable to economic conditions, and even closure. Spending years of work on research only to publish in a journal that will “die quickly” because it has no readership, Artaxo said, is a “waste of time, money, and everything.”

https://eos.org/features/raising-the-visibility-of-latin-american-science?utm_source=EosBuzz&mkt_tok=OTg3LUlHVC01NzIAAAGPn_oOHVi0kvmCTw3CgKbXeupSS1QCxpmn268hIIKeAyDQUVdkBFkgIbcxTc03AIL6XX0nWTojPbOjG3pCPSE6r-uPKsBAnjf4p6BgbOqQ

R to @JChengWSJ: NYT: "The surge of migrants entering the United States across the southern border increasingly includes people from a surprising place: China." https://www.nytimes.com/2023/11/24/us/politics/china-migrants-us-border.html https://nitter.hongkongers.net/JChengWSJ/status/1728602221992948092#m

Periodic reminder of what fMRI's BOLD signal is measuring, and its temporal dynamics:

"blood oxygenation level–dependent (BOLD) contrast. [...] increased signal in a voxel measured with an EPI [echo planar imaging] sequence indicates recent neuronal activity
because of the relative increase in local blood oxygenation that accompanies such activity. The temporal profile of this BOLD response, known as the hemodynamic response function, looks like a bell curve with a long tail, peaking around 4 to 5 seconds after local neural activity and returning to baseline after 12 to 15 seconds."

From "Principles of Neural Science", Kandel et al. 6th edition, page 115.

No matter how fast the EPI imaging is (~100 ms), the BOLD dynamics makes GCaMP look lighting fast. Temporally deconvolving BOLD is possible, to a point, but remember its spatial resolution is measured in millimetres, whereas neuronal somas measure ~0.025 millimetres.

#fMRI #BOLD #neuroscience

Further evidence that the pressure in MDPI for fast turnaround is compromising article quality: https://pubpeer.com/publications/411821120F65A4609F4665C967E782#2