Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
The Texas Attorney General & #TXSupremeCourt are preventing a woman w/a life-threatening, nonviable pregnancy from having an abortion.
Donate to help turn Texas blue TODAY.
https://secure.actblue.com/donate/txblue24?refcode=gabamasto
Thiago Carvalho
boosted
'Given the ability of low-affinity Glut2 to bidirectionally transport glucose along a concentration gradient, its prompt removal from the cell surface is instrumental to prevent glucose leakage in glucose-depleted environments. In contrast, the high-affinity Glut1, whose expression does not decrease in inflammatory sites, can sustain glucose uptake in conditions of low glucose availability.'
Thiago Carvalho
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@cyrilpedia Bill Balch's telling of that story (particularly his impression of Woese on the phone to the NYT) is ROTFLOL funny.
"We demonstrate a direct effect of ACh on worms, reducing their viability and fecundity via helminth muscarinic ACh receptors, with effects promoted by inhibition of acetylcholinesterase, an helminth-secreted enzyme."
Thiago Carvalho
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Not that the category is large, but “The eviction risk for Black households earning more than $80,000 is still higher than it is for a white household earning under $20,000 a year.“
https://www.newamerica.org/better-life-lab/articles/eviction-health-risks-black-children/
#the1619Project #BlackMastodon
Peek-a-bowl.
#Ceramics #stoneware #pottery #Handmade #Art #ceramic #artgallery #artmastodon
@madparreira.bsky.social
Thiago Carvalho
boosted
Mammoth: a simpler, discovery-focused Mastodon app.
It’s nice to see discussion of more Mastodon apps. The article also lists others like #Icecubes which I like a lot.
#Mastodon #Fediverse
https://www.theverge.com/2023/12/7/23991158/mammoth-2-app-mastodon
Let's mouth-pipette a toast to the good old days...
'It was Woese’s new approach to doing phylogeny that produced this completely unexpected and very newsworthy result. His method, which seems impossibly tedious now that we can sequence whole genomes over lunch, involved dangerous amounts of radioisotopes, highly flammable solvents, and weeks to months of effort to produce, for any cultured microbial species, an ‘oligonucleotide catalog’. '
Thiago Carvalho
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New York Times, 1977
'One flight of fancy advanced by Dr. Woese, with an accompanying smile, is that the presence of this class of organisms might explain why life evolved here and not on the earth's sister planet, Venus.
The rationale goes as follows: Clouds of carbon dioxide originally enveloped both planets, but methanogens developed on earth and digested much of the cloud and in turn produced the hydrocarbons that developed into higher forms of life. But on Venus, according to this line of speculation, the lack of methanogens allowed the carbon dioxide to accumulate to the point that the so‐called “greenhouse effect” took over the Venusian surface, in turn making it too hot for life to evolve.'
Thiago Carvalho
boosted
On this day in 1935: Lafayette B Mendel died, co-discovered vitamins A and B, lysine and tryptophan #ThisDayInBiotech
"The NADINA trial aims to compare the efficacy of neoadjuvant ipilimumab plus nivolumab with that of adjuvant nivolumab in macroscopic stage III melanoma. Patients diagnosed with recurrent or de novo stage III melanoma, including up to three in-transit metastases, will be randomly assigned to receive neoadjuvant treatment or adjuvant treatment."
#Immunology #Immunotherapy
“En este periplo imaginario, sin embargo, todo empieza y concluye ante Las meninas de Velázquez. Mi vida está ligada a esta obra fascinante, se aparta de ella y vuelve a ella sin cesar, encontrándola siempre en su camino”.
https://elpais.com/babelia/2023-12-09/la-gran-aventura-europea-de-jorge-semprun.html
Thiago Carvalho
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Portuguese journalist and author Almeida Garrett died #OTD in 1854. In 1843, he published Romanceiro e Cancioneiro Geral; two years later, he wrote the first volume of his historical novel O Arco de Santana. This latest signified a change in Garrett's style, leading to a more complex and subjective prose with which he experimented at length in Viagens na Minha Terra. via @wikipedia
Books by Almeida Garrett at PG:
https://www.gutenberg.org/ebooks/author/7478
Thiago Carvalho
boosted
Apparently the BBC (UK) has had 144 complaints about a recent episode of #DoctorWho because it contained an openly #trans character.
I'm going to make a complaint to the BBC that there weren't enough #transgender characters in Doctor Who. I would love if 144 other people did the same thing. Here's the link: https://www.bbc.co.uk/contact/complaints/make-a-complaint/#/Complaint
(For your easy reference: "The Star Beast" aired on 25/11/2023, and the trans character is called Rose.)
Reply when you've done it, so we can count us all. When we get to 145, everyone... gets a free BLÅHAJ? 🦈
Thiago Carvalho
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"The best fiction, nonfiction, history and sci-fi books Scientific American staff read in 2023" by Brianne Kane for @scientificamer | Honored for #OurFragileMoment to be included 🙂https://www.scientificamerican.com/article/55-books-scientific-american-recommends-in-2023/
"A new study, published on Friday in the journal Science Advances, bolsters Williams’s theory using a trove of human DNA. Researchers found hundreds of mutations that could boost a young person’s fertility and that were linked to bodily damage later in life."
https://www.nytimes.com/2023/12/08/science/fertility-genes-lifespan.html
Thiago Carvalho
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Research Specialist III
Moffitt Cancer Center
See the full job description on jobRxiv: https://jobrxiv.org/job/research-specialist-iii/?feed_id=67384
#ScienceJobs #hiring #research
https://jobrxiv.org/job/research-specialist-iii/?feed_id=67384
Thiago Carvalho
boosted
Dopamine Prediction Error Signaling in a Unique Nigrostriatal Circuit is Critical for Associative Fear Learning https://www.biorxiv.org/content/10.1101/2023.12.08.570564v1?med=mas
Thiago Carvalho
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.@us_fda approves two gene therapies for sickle cell disease: @bluebirdbio's #Lyfgenia and @vertexpharma & @crisprtx's #Casgevy, the first treatment in the US based on CRISPR gene editing technology #NBTNewsBeat https://www.reuters.com/business/healthcare-pharmaceuticals/us-approves-two-gene-therapies-sickle-cell-disease-2023-12-08/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
