Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"Os interesses da indústria farmacêutica são incompatíveis com o escrutínio que os cidadãos têm o direito de fazer aos gastos públicos com medicamentos, mas quem ganha o braço-de-ferro é a indústria."
Lithographic print on wood, 12x15cm by @madparreira
#Art #Prints #Printmaking #Handmade #artgallery #artmastodon
Thiago Carvalho
boosted
Book 29: “New Suns: Original Speculative Fiction by People of Color” edited by #NisiShawl.
Read this after learning a Mastodon mutual is in it. Tend to have a hard time with short story collections, but this one slowly grew on me. I loved the author bios and having a better sense of what informed their pieces, especially as POC authors in this genre. “New Suns” makes up for some of its less successful parts by gathering these voices together into a greater whole.
Thiago Carvalho
boosted
Convolutional Gene Expression Detective 🕵️♀️ : Decoding mRNA Features to Predict Protein Abundance.
Another excellent preLights post from Benjamin Dominik Maier covering a recent #preprint from Patrick Maximilian Schwehn & Pascal Falter-Braun.
Check it out! 👀
#preLight 👉 https://prelights.biologists.com/highlights/inferring-protein-from-mrna-concentrations-using-convolutional-neural-networks-v3/
#bioinformatics #NeuralNetworks #MachineLearning #proteomics #transcriptomics
Thiago Carvalho
boosted
@cyrilpedia @FrenchHistory he famously "remade" the port by having cannons pointing at the city rather than at the sea
"Our study reveals an imbalance in nitrogen-recycling bacteria and, specifically, C. freundii in relapsed multiple myeloma patients. We established a critical role for C. freundii in inducing bortezomib resistance."
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(23)00450-3#secsectitle0080
Thiago Carvalho
boosted
with the US CDC urging masking, making it mandatory in health settings amid the rise of variant JN.1 and WHO today listing that as a separate variant of interest - The Netherlands recording it's highest wastewater viral load ever (and they've been leaders in monitoring)
You would think Canada and the provinces would be holding urgent pre-Christmas press conferences, and enacting some measures
Dead silence
We live in an insane timeline of utter negligence
"Upon reflection, I have realised that this fascination and appeal to dinosaurs could be used for good. The attention-grabbing effect of dinosaurs may offer a means of captivating audiences and explaining complex or difficult subjects."
https://www.cell.com/current-biology/fulltext/S0960-9822(23)01573-7
O Pesadelo do Moedas
"Broad, tranquil avenues of tall trees link parks, squares and allotments, forming a circular oasis around a city centre that itself is largely car-free and where, aside from a passing tram, the dominant sound is conversation, birdsong and even the persistent chirping of cicadas."
https://www.theguardian.com/environment/2023/dec/20/vitoria-gasteiz-spanish-city-rejected-cars
Thiago Carvalho
boosted
Several fully-funded PhD positions are available in the new AI centre of excellence at Sussex. Anyone interested in a project involving neuromorphic engineering, spiking neural networks please get in touch!
https://www.sussex.ac.uk/study/fees-funding/phd-funding/view/1686-Sussex-AI-PhD-Studentship
Thiago Carvalho
boosted
Interested in #epigenetics? Scientists find that high-sugar diets have a transgenerational effect in fruit flies as behaviour changes are passed from mother to offspring. #Drosophila #Neuroscience https://elifesciences.org/articles/85365?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Thiago Carvalho
boosted
Universities: why are you still on Twitter/X?
As I have explained before, I left the platform formerly known as Twitter at the end of August 2023 and haven't looked back. Many of my friends and colleagues have quit too, most of them setting up accounts on Bluesky and/or Mastodon. In recent months, a number of big companies have also stopped advertising on Twitter/X too. It's not just the systematic amplification of hateful tweets from a variety of antisocial bigots,…
http://telescoper.blog/2023/12/20/universities-why-are-you-still-on-twitter-x/
Great piece - I expected the neglected researchers, the public health effects of deprivation, the normally peace-loving organism thrust into the role of pathogen, British imperialism as the secret ingredient that makes any problem worse... But I did not see the volcano coming :)
(via. The Browser)
https://openthemagazine.com/features/living/amnesia-hour/?ref=thebrowser.com
Thiago Carvalho
boosted
Scientists created a searchable #FluorescenceMicroscopy image resource of #Drosophila GAL4 driver expression patterns with single neuron resolution. Check out some of the images below. #Neuroscience #12DaysOfeLife https://elifesciences.org/articles/80660?utm_source=mastodon&utm_medium=social&utm_campaign=organic_12Days
Thiago Carvalho
boosted
My annual call!
Please suggest a cool paper/preprint in your field in the last year or so!
For a course I teach, I am collecting papers on: cell/dev bio, microbio, neuro, maths/stats/CS/chem/phys applied to biology.
Students use one paper as the basis for a "research grant application" that they will write. So papers that are cool but also open doors to future study are ideal! Do you know one? It can be your own, I don't mind!
Last year's selection: https://quantixed.org/2023/01/14/papers-for-md9a8-2023-edition/
Thiago Carvalho
boosted
A new protein-ligand docking software with an improved method of molecular conformation optimization https://chemrxiv.org/engage/chemrxiv/article-details/65816d1066c138172990436e
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#proteomics #prot-preprint
Maybe *literal* inbreeding is not the best way to intelligent elites?
"The aristocracy and celebrities are in thrall to medical quackery that while useless can be far from harmless"
Thiago Carvalho
boosted
In today's episode Arazoo Ferozan discusses how the Sun King remade the port city of the Marseille, France's gateway to the Mediterranean. https://www.thefrenchhistorypodcast.com/marseille-the-mediterranean-the-sun-king-by-arazoo-ferozan/?fbclid=IwAR0WDhFynRtG4a493NhHmrvqb3NKXWhG1UzBR4_iANqzdhleyWblktyzA5U
Thiago Carvalho
boosted
Humans might have driven 1,500 bird species to extinction — twice previous estimates
"Novo Nordisk also faces a number of potential obstacles that could still hamper its expected growth. The surge of popularity in the drugs — fuelled in part by slimming celebrities — has caused a supply shortage and created a booming black market. Concerns rumble about side effects. Rival Eli Lilly has won approval for its own obesity drug, which could be more effective and currently has a lower list price."
https://www.ft.com/content/d4d289a7-e1a5-4848-8e7e-b592f7018722
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
