Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Thiago Carvalho
boosted
Immigration : au-delà de l’indignation, quelle alternative à gauche ?
Source: Patrick Haddad
"The most important challenge is that of fairness or “linguistic justice”. A common language is a bit like a telephone network: the more people know a language, the more useful it becomes to communicate. The question of fairness arises because individuals face very different costs to access the network and are on an unequal footing when using it. Those who learn English as a second language incur learning costs, while native speakers can communicate with all network members without incurring such costs. It’s like getting the latest smartphone model and sim card with unlimited data for free."
"Irreproducible experiments, projects that failed to meet their goals, datasets we collected but never managed to analyze, and freezers full of unusable samples have taught us the hard way lessons that have led to these 10 simple rules for managing laboratory information."
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011652
Thiago Carvalho
boosted
"The rate of serious medical complications increased in hospitals after they were purchased by private equity investment firms, according to a major study of the effects of such acquisitions on patient care in recent years."
https://www.nytimes.com/2023/12/26/upshot/hospitals-medical-errors.html
Thiago Carvalho
boosted
"La noticia también ha sacudido a la Agencia Europea del Medicamento (EMA), que se ha dirigido a la FDA para conocer más detalles. “Estamos al tanto de la comunicación sobre casos de neoplasias malignas secundarias con algunos medicamentos de células T con CAR. Nos hemos puesto en contacto con la FDA para recopilar más información sobre los casos notificados a las autoridades estadounidenses”, explica por escrito un portavoz."
"To build a comprehensive hemocyte single-cell atlas of larval hemocytes, we integrated whole transcriptomes of hemocytes both in circulation and in the lymph gland 72, 96, and 120 hours after egg laying"
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011077
Thiago Carvalho
boosted
Macrophages are essential immune cells that reside in all tissues. Some macrophages arise from monocytes in the blood, but during fetal development they also come from a unique pathway!
We still have a lot to learn, but here I'll describe how Zhao et al. (2023) used mouse models to uncover hints about which progenitor cells create tissue-macrophages.
https://doi.org/10.1016/j.celrep.2023.113364
#Macrophages #MouseModel #Immunology #Immunity #scRNAseq #FlowCytometry #Research #JournalArticle #JournalClub
1/9🧵
"La noticia también ha sacudido a la Agencia Europea del Medicamento (EMA), que se ha dirigido a la FDA para conocer más detalles. “Estamos al tanto de la comunicación sobre casos de neoplasias malignas secundarias con algunos medicamentos de células T con CAR. Nos hemos puesto en contacto con la FDA para recopilar más información sobre los casos notificados a las autoridades estadounidenses”, explica por escrito un portavoz."
'The Russian government’s invasion cut off pharmaceutical supplies (...) More than 100,000 Ukrainians with H.I.V., for example, were threatened with losing access to the lifesaving antiretroviral medications they needed.'
https://www.nytimes.com/2023/12/25/opinion/global-immune-system-public-health.html
Thiago Carvalho
boosted
"Tumor interstitial fluid nutrient composition closely resembles kidney interstitial fluid, suggesting that tissue-specific factors unrelated to the presence of cancer exert a stronger influence on nutrient levels than tumor-driven alterations"
#Metabolism
Thiago Carvalho
boosted
Thiago Carvalho
boosted
Exciting venture ahead as Michael Bader and colleagues at #mdcBerlin and Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) found Trypto Therapeutics to bring their serotonin-regulating agent, TPT-004, to market! Join the journey of innovation! #StartUp
Read more:
https://www.mdc-berlin.de/news/press/new-agent-regulates-serotonin-production
Thiago Carvalho
boosted
"Younger people—typically at low risk—are especially vulnerable to COVID-related heart attacks, with the sharpest relative rise in deaths occurring in people ages 25 to 44, research by Los Angeles’ Cedars-Sinai Medical Center shows." https://www.prevention.com/health/health-conditions/a46131357/heart-problems-after-covid/
Thiago Carvalho
boosted
"Here, by studying 98 tissues from 27 deceased transplant organ donors we demonstrate that despite representing less than 5% of circulating Tregs, fully functional, thymically derived CD8+FOXP3+ Tregs are highly enriched in human tissues particularly in non-lymphoid tissues and bone marrow, where they reside as CD25lo/-CD8+CD69+CD103+TLR9+HELIOS+FOXP3+ Tregs."
#Preprint #Immunology
Thiago Carvalho
boosted
'Candice Breitz, Deborah Feldman and Masha Gessen are just the latest to be ‘lectured’, as Eyal Weizman put it, ‘by the children and grandchildren of the perpetrators who murdered our families and who now dare to tell us that we are antisemitic’.'
https://www.lrb.co.uk/the-paper/v46/n01/pankaj-mishra/memory-failure
Thiago Carvalho
boosted
'The book that gives us Calvino the romantic and Calvino the craftsman in equal measure is “If on a Winter’s Night a Traveler.” It is the book that makes people fall in love with Calvino, because it is a book about falling in love through reading—specifically, “reading Italo Calvino’s new novel, If on a winter’s night a traveler.”' (Illustration by Daniele Castellano)
https://www.newyorker.com/magazine/2023/03/06/the-worlds-of-italo-calvino
"O racismo e a ausência de sentido crítico em relação ao colonialismo, em Portugal, vêm de longe. Não vale a pena negar que é assim. A inferiorização de pessoas e uma descrição idealizada do processo dos Descobrimentos fizeram parte dos manuais escolares da grande maioria dos portugueses."
https://www.publico.pt/2023/12/27/opiniao/opiniao/ventura-traficante-louro-prensado-2074907
Thiago Carvalho
boosted
Nature is going into full Buzzfeed mode with its headlines
Just waiting until that happens to research paper titles as well…
Thiago Carvalho
boosted
Happy 200th Birthday to French chemist and microbiologist Louis Pasteur!
He is renowned for his discoveries of the principles of vaccination, microbial fermentation, and pasteurization, the last of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes & preventions of diseases, which laid down the foundations of hygiene, public health & much of modern medicine.
Louis Pasteur at PG:
https://www.gutenberg.org/ebooks/search/?query=louis+pasteur&submit_search=Go%21
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
