Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
I was on Twitter/X for several years and as the COVID pandemic started it became a key way for people to communicate--scientists, clinicians, policy-makers, advocates. But since Musk took over many have fled and the place has become incredibly toxic (yes, I am slow to learn that not all things get better...). It's just really filled with hate now of all kinds. I just deleted my account. I feel free.
Thiago Carvalho
boosted
Près de 25 000 morts à Gaza, pourquoi ce chiffre de victimes de l’offensive israélienne est sous-estimé
Source: Léa Masseguin
Thiago Carvalho
boosted
'Our findings suggest that the GFRAL neuronal axis is key in coordinating the adaptive thermogenic response across multiple tissues and adipose depots, thereby ensuring metabolic homeostasis during mitochondrial stress.'
#Preprint
Thiago Carvalho
boosted
"Jawed vertebrates have had at least two genome duplications, and Dr. Pascual-Anaya and his colleagues were curious whether the hagfish showed evidence of them too. They discovered that one of these duplications must have happened before the two groups of vertebrates split — the hagfish genome has signs of it — but the other was most likely after the fork in the evolutionary road. What’s more, they confirmed a suspicion other scientists had raised, that an ancestor of both the hagfish and the lamprey, another jawless wonder, at some point tripled its genome."
https://www.nytimes.com/2024/01/16/science/hagfish-slime-eel-genome.html
'Neuroscientist Anita Lüthi would like to see future studies elucidate how the PV neurons decrease brain connectivity without shutting it down completely. “Sleep is not a coma; we are not totally knocked out,” says the University of Lausanne-based researcher. Perhaps there’s a parallel system that keeps some basal connectivity intact, she hypothesizes. Dan says the work is also getting a lot of attention from anesthesiologists, who are interested in knowing how the brain’s response to different forms of anesthesia compares to its response to sleep.'
https://www.pnas.org/post/journal-club/mouse-study-sheds-light-brain-powers-down
Thiago Carvalho
boosted
'More recently, Dr. Wooller and his colleagues figured out how to use mammoth tusks to track where the animals lived over the course of their life. They did so by measuring strontium, an element found in trace amounts in the plants the animals ate.'
Thiago Carvalho
boosted
"There is a quote by Theodosius Dobzhansky that goes: “Nothing in biology makes sense except in the light of evolution.” In response, I wish to offer up a corollary: “Nothing in evolution makes sense except in the light of molecular biology and genetics.”* Building a comprehensive model of evolution requires a thorough understanding of the molecular events involved. Here is where experimental evolution coupled with modern molecular biology and next-generation sequencing can create new ways for us to answer fundamental questions about the nature of evolution."
Correction: written by Ira Zibbu (and not @RELenski as I'd originally posted)
https://the-ltee.org/who-moved-my-genes-analyzing-chromosomal-rearrangements-in-the-ltee/
Thiago Carvalho
boosted
Squirrel! Glazed stoneware by @hunchbacksociety
#art #ceramics #stoneware #handmade #artgallery #stoneware
@madparreira.bsky.social
Thiago Carvalho
boosted
"Colitis is a frequent and severe adverse event in patients treated with antibodies targeting the checkpoint inhibitor cytotoxic T-lymphocyte protein 4 (CTLA-4), but the underlying mechanisms leading to this reaction remain unclear."
"Em vez de encarar um conflito que é real, o Chega intensifica potenciais conflitos irrelevantes: entre o povo e a comunidade cigana, entre os portugueses e os imigrantes, entre quem é de bem e a comunidade LGBTQI+ ou entre os cidadãos e os políticos que, já se sabe, são todos uns corruptos. A fórmula é simples, mas pelos vistos eficaz. As pessoas gostam de ter inimigos e a quem culpar pelos seus infortúnios, o Chega tem uma lista de inimigos em carteira para apresentar."
Thiago Carvalho
boosted
"We tend to think about species moving north [or south] rather than changing appearance".
This is my ex's cousin Richard on the efferct of #climatechange on #insects #Entomology
https://www.bbc.com/news/uk-england-devon-68008127?xtor=AL-72-%5Bpartner%5D-%5Bbbc.news.twitter%5D-%5Bheadline%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D&at_bbc_team=editorial&at_campaign=Social_Flow&at_link_type=web_link&at_ptr_name=twitter&at_format=link&at_link_origin=BBCScienceNews&at_medium=social&at_link_id=4061BBDC-B5CA-11EE-BACF-6D9AD0B4AF07&at_campaign_type=owned
Thiago Carvalho
boosted
Here's Tom Gauld's take on the #ArtificialIntelligence in #Art...
If he's right the writing on the gallery wall is about to get a lot more obscure....
Fans of cutting edge #contemporaryart will be grinding their teeth & complaining that this unfairly trivialises artists intent & commitments to avant-garde creativity.
either way it made me smile!
So lets not take the cartoon too seriously!
Thiago Carvalho
boosted
As would be expected, measures such as masks and air filtration reduced spread of Covid
#COVID
https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad738/7517603
'The paper, published Tuesday in JAMA, found that the death rate from breast cancer had fallen to 27 per 100,000 women in 2019 from 48 per 100,000 in 1975. That includes metastatic cancer, which counted for nearly 30 percent of the reduction in the breast cancer death rate.
Breast cancer treatment has improved so much that it has become a bigger factor than screening in saving lives, said Ruth Etzioni, a biostatistician at the Fred Hutchinson Cancer Center.'
https://www.nytimes.com/2024/01/17/health/cancer-deaths-decline.html
“The U.S. market is the bank for pharmaceutical companies,” said Ameet Sarpatwari, an expert in pharmaceutical policy at Harvard Medical School. “There’s a keen sense that the best place to try to extract profits is the U.S. because of its existing system and its dysfunction.”
https://www.nytimes.com/2024/01/17/health/us-drug-prices.html
Thiago Carvalho
boosted
'The Brazilian Society of Palaeontology (BSP) has recently taken steps to become more involved in the repatriation of fossil specimens — a central issue in the global palaeontological community, as interest in combating scientific colonialism grows — both through collaboration with researchers and other Latin American scientific associations. We discuss our experience, including the challenges we have faced and how we have overcome them, in the hope of inspiring other scientific societies to play their part.'
"There is a quote by Theodosius Dobzhansky that goes: “Nothing in biology makes sense except in the light of evolution.” In response, I wish to offer up a corollary: “Nothing in evolution makes sense except in the light of molecular biology and genetics.”* Building a comprehensive model of evolution requires a thorough understanding of the molecular events involved. Here is where experimental evolution coupled with modern molecular biology and next-generation sequencing can create new ways for us to answer fundamental questions about the nature of evolution."
Correction: written by Ira Zibbu (and not @RELenski as I'd originally posted)
https://the-ltee.org/who-moved-my-genes-analyzing-chromosomal-rearrangements-in-the-ltee/
Thiago Carvalho
boosted
After a tough day, a tiny octopus finds somewhere safe to have a snooze, in this handy clam shell.
Photographed in Lembah Strait, off Indonesia, by Franco Tulli (Australian Nature Photographer Awards 2021).
https://theguardian.com/artanddesign/gallery/2021/aug/27/australian-geographic-nature-photographer-of-the-year-2021-in-pictures #octopus #octopi #photography
@artinsociety
Thiago Carvalho
boosted
'More recently, Dr. Wooller and his colleagues figured out how to use mammoth tusks to track where the animals lived over the course of their life. They did so by measuring strontium, an element found in trace amounts in the plants the animals ate.'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
