Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Umberto Eco has a cogent essay about how to spot the signs of what he calls "Ur-Fascism", or the essential components of fascism.

I turned it into an infographic, because, well, you know why...

Original article here in PDF: https://www.pegc.us/archive/Articles/eco_ur-fascism.pdf

#fascism #authoritarianism #elections #infographic #democracy

https://journals.biologists.com/dev/article/151/3/dev201867/342647/Tracking-early-mammalian-organogenesis-prediction now in @Dev_journal

Thanks to all the #OpenAccess leaders who shared their take on "Community over Commercialization" during #OAWeek. Read about what's happening in Chile & all over the world in our series of profiles about efforts to advocate for open knowledge sharing.https://sparcopen.org/impact-story/the-impact-of-embracing-community-over-commercialization/

Mary Shelley died on this day in 1851 and left us, besides one of the farthest-seeing books of all time, her abiding wisdom on what makes life worth living https://t.co/BPelivt92s

"In the 1970s, working at the University of Maryland, Daly pioneered the field of ecological economics, which models the biophysical reality that delimits all economies. “The human economy,” wrote Daly, “is a fully contained wholly dependent growing subsystem of the non-growing ecosphere” — a commonsense observation that amounted to heresy in mainstream economics."

https://theintercept.com/2023/10/29/william-nordhaus-climate-economics/

Reminds me of the divide between psychologists and cell biologists when it comes to neuroscience.

In this Research Article, Michelle Urman et al (Lee Lab at University at Albany) show that aging disrupts spatial regulation of Notch activation in the C. elegans germline, leading to the mislocation of the Notch-responsive GSC pool, leading to reproductive decline
https://journals.biologists.com/bio/article/13/1/bio060261/341335
#OpenAccess

Hey y’all! As I diversify beyond the ex-Bird App, I’m trying to expand my reach to keep folks up to date with the latest.

I’m tantalizingly close to 1,000 on Mastodon. Could I trouble you for a boost from the #StarTrek community to follow me here?

Mass Spec–Based Single-Cell Proteomics Grapples with Heterogeneity https://www.genengnews.com/topics/omics/mass-spec-based-single-cell-proteomics-grapples-with-heterogeneity/

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#proteomics #prot-article

'Vertex Pharmaceuticals of Boston announced Tuesday that it had developed an experimental drug that relieves moderate to severe pain, blocking pain signals before they can get to the brain. It works only on peripheral nerves — those outside the brain and the spinal cord — making it unlike opioids. Vertex says its new drug is expected to avoid opioids’ potential to lead to addiction.'

https://www.nytimes.com/2024/01/30/health/vertex-pain-medicine-non-opioid.html

'How could one come to know the motions of wit? Here Cavendish left off her quarrel with Hobbes and turned to the “Modern Microscopical or Dioptrical Writers”—Descartes, Hooke, Boyle—whose splendid and costly instruments, she insisted, had deceived them as to the true nature of motion. In her 1666 treatise, “Observations upon Experimental Philosophy,” she complained that the lenses of microscopes were fractured, flawed, and unevenly shaped, and that their mirrors produced distorted figures, like “a high heel to a short legg.” Lice appeared as large as lobsters, while the wings of birds were abnormally stretched, their feathers streaked with garish colors. “How shall a feather inform us of the interior nature of a Bird?” she wondered.'

https://www.newyorker.com/magazine/2024/02/05/pure-wit-the-revolutionary-life-of-margaret-cavendish-francesca-peacock-book-review

"Here, we explored the impact of dietary interventions on both immunity and the microbiota in a highly controlled clinical setting, with each participant sequentially consuming distinct diets for 2 weeks in random order. To our knowledge, this study represents the first multiomics study investigating the impact of ketogenic and vegan diets on humans."

https://www.nature.com/articles/s41591-023-02761-2

English novelist Mary Wollstonecraft Shelley died #OTD in 1851. She is best known for writing the Gothic novel Frankenstein; or, The Modern Prometheus, which is considered an early example of science fiction. She edited and promoted the works of her husband, the Romantic poet and philosopher Percy Bysshe Shelley. Her historical novels include Valperga and Perkin Warbeck, the apocalyptic novel The Last Man and her final two novels, Lodore and Falkner. via @wikipedia

#books #literature

If allegations against .0004% of UNWRA's employees are enough for US Admin to cancel all US funding for food & water to 2.3 million Palestinians in Gaza, then why isn't open support by 1/3 of ***the entire ministry of the government of Israel*** for the ethnic cleansing of Palestinians in Gaza, enough to cancel all US funding to their organization?

/thinking/

https://twitter.com/EpshtainItay/status/1751668300008833149

Expanding the ligandable proteome by paralog hopping with covalent probes https://www.biorxiv.org/content/10.1101/2024.01.18.576274v1.full.pdf+html

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#proteomics #prot-preprint