Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
RT @EricTopol@twitter.com
Just out @NEJM@twitter.com, a "milestone"
The level of neutralizing antibodies induced by Covid vaccines has been established as a correlate of protection, i.e. a surrogate endpoint for predicting clinical outcomes and use for regulatory approvals
https://www.nejm.org/doi/full/10.1056/NEJMp2211314?query=featured_secondary
🐦🔗: https://twitter.com/EricTopol/status/1601600918109425665
Thiago Carvalho
boosted
Scientists Are Uncovering Ominous Waters Under #Antarctic
At base of Antarctica's #icesheet is an area size of Germany & France combined feeding #meltwater into a super-pressurized, 290mi river running to the sea. That could be bad news for #sealevelrise
https://bit.ly/3ApjLJo
Thiago Carvalho
boosted
Fellow librarians -- please pass around word about @libraryland.social - a Mastodon instance set up for public library workers to share ideas, inspirations, questions, announcements and the like. If you're looking for a new home to move to after landing at mastodon.social -- that might be your new home.
From Kevin Foster and collaborators
"The order and identity of incoming symbionts is critical for health, but what determines the success of the assembly process remains poorly understood. Here we develop ecological theory to identify factors important for microbial community assembly. Our method maps out all feasible pathways for the assembly of a given microbiome—with analogies to the mutational maps underlying fitness landscapes in evolutionary biology."
#Microbiology #MucosalImmunology
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001116
Thiago Carvalho
boosted
Marrocos eliminar a Ibéria do mundial só pode ser um sinal
'Experts say the prevalence of middle-class professionals in the ranks of the extremists makes them a far bigger threat than the radical left Baader-Meinhof gang that terrorised Germany in the 1970s. “This is a form of terrorism that has emerged out of the mainstream of society,” says Sebastian Fiedler, a Social Democrat MP and police detective.'
https://www.ft.com/content/b7565be2-0130-4d1d-9ace-c3f4787775d8
That's how you start an abstract:
"In the beginning it was simple: we injected a protein antigen and studied the immune responses against the purified protein. This elegant toolbox uncovered thousands of mechanisms via which immune cells are activated. However, when we consider immune responses against real infectious threats, this elegant simplification misses half of the story: the infectious agents are typically evolving orders-of-magnitude faster than we are."
Thiago Carvalho
boosted
Ada Lovelace, née Augusta Ada Byron, was born #OTD in 1815. A mathematician and the first published computer programmer, she offered a prescient vision of what computing would become.
Portrait: Margaret Sarah Carpenter (1836)
Thiago Carvalho
boosted
On this day in 1934: Howard M Temin born, won 1975 #NobelPrize for discovering reverse transciptase #ThisDayInBiotech
Thiago Carvalho
boosted
This whole “Twitter Files” nonsense has made me realize that I need to *leak* my next research article instead of publishing it.
'For Henry James, our man in Italy, “There is something ridiculous in talking of Venice without making him almost the refrain.”
The year is 1882, the American writer is not yet 40, and the him is Vittore Carpaccio: the painter of the early Renaissance whose narrative cycles of Christian saints decorate churches and confraternities all around the maritime city.'
Thiago Carvalho
boosted
New #preprint about PENSA, our flexible #OpenSource software package for comprehensive and thorough investigation of biomolecular conformational ensembles:
https://arxiv.org/abs/2212.02714
In three real-world examples, we show how it can be used to understand an #enzyme mechanism, #DNA #forcefield parameters, and #signaling in an #opioid #receptor.
Please share widely with the #MolecularDynamics #simulation #CompChem #MolBio #StructuralBiology #GPCR communities!
Feedback and ideas are always welcome.
Thiago Carvalho
boosted
Nice review covering transmission, pathogenesis of airborne viruses: “Airborne transmission of respiratory viruses” https://www.science.org/doi/full/10.1126/science.abd9149
Thiago Carvalho
boosted
Impressive how vigorous, crisp, and sound Anthony Fauci is at age ~82. Such an important voice.
We need many more scientifically literate and powerful voices like this willing to go into government and public service around the globe.
From @sciencemagazine podcast:
https://podcasts.apple.com/pt/podcast/science-magazine-podcast/id120329020?l=en&i=1000589458084
Thiago Carvalho
boosted
The Albert Khan Museum in France has just made available for download thousands of early autochrome photos from around the world: Khan, a banker, had top French photographers travel the world documenting everyday aspects of global life which he believed would soon vanish as the world rapidly developed.
Such prescience.
https://www.rferl.org/a/color-photos-archive-planet-albert-kahn-history/32166970.html
"As we know, because we’ve gone through it several times, the problem comes a month or two later. There will be a massive wave of covid infections, and this means that there’s going to be a lot of people with heavy symptoms, and, inevitably, there will be some deaths—a lot more covid-related deaths than what China is used to. Does Xi then reinstate a very draconian lockdown? Does he go to some partial level of lockdown, but push through with it? It’s unclear at this point. Right now, the optics are good. There’s an opening. People are a little bit more satisfied, a little bit less frustrated. For the next month or so, it’s going to be good. But when China does get this massive wave of infection and hospitalization, what is Xi going to do?"
https://www.newyorker.com/news/q-and-a/why-xi-jinping-changed-his-mind-on-zero-covid
Thiago Carvalho
boosted
Thiago Carvalho
boosted
We're not lion: The 2022 Comedy Wildlife Photography Awards are a good laugh
https://www.npr.org/sections/pictureshow/2022/12/10/1141604273/comedy-wildlife-photography-awards-funny-animals-photos
Thiago Carvalho
boosted
The Bregenz Festival is famous for staging some of the most mind-blowing spectacles. Verdi’s opera, “A Masked Ball,” featured a stage that looked like a giant book being opened by a skeleton. The show took place in 1999 on Lake Constance in Bregenz, Austria. It astounds me every time I see it! What do you think?
#arts #skeleton #theatre #production #musical #opera #weird #followback #austria #theater #actor
Thiago Carvalho
boosted
Scary how much this describes the current situation in Austria as well. We are about to get orbanized. Well, we've been about to get orbanized for a while...
---
RT @TimothyDSnyder
Six years ago, I published a list of political advice following Trump's election, which became the pamphlet "On Tyranny." The history of #fascism was important in that advocacy. I wrote then that "post-truth is pre-fascism," which has proven true. https:…
https://twitter.com/TimothyDSnyder/status/1601231090274144257
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
