Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
December 27, 1831, HMS Beagle with Charles #Darwin on board departs Plymouth harbor, England, for a survey of South America. The rest is history ⛵
Thiago Carvalho
boosted
Our recent paper about rangers (or rather the lack of: https://www.nature.com/articles/s41893-022-00970-0) made the cover of Nat Sustainability 🥳
I hope it will help attract the attention of #COP15 #biodiversity folks so that they start considering the issue seriously.
Since the cover mentions nothing else, I am starting to wonder if the website is not simply reading cookies and generating a specific cover for any author...🤔
Thiago Carvalho
boosted
Maybe the greatest contemporary street photographer and one of the greatest ever, Alex Webb is known for his images full of colour, people, complexity and reading planes. He takes this shot in Nuevo Laredo, Mexico: one of the masterpieces of the stunning book “La Calle”, which collects his shots taken in Mexico between 1975 and 2007. Since 1979 Alex Webb is one of the leading photographers of Magnum Photos
"Most jazz musicians practice by themselves; “woodshedding” is part of the life. But Rollins’s notion of practicing expanded into nearly all of his life, to the point where you wonder whether he’s practicing in preparation for the thing or if practice is the thing itself — whatever the thing may be: a gig, a recording, a new level of musical expression, a higher consciousness, the next life."
https://www.nytimes.com/2022/12/20/books/review/saxophone-colossus-aidan-levy.html
Thiago Carvalho
boosted
Depression is the most common mental health condition in the world, so understanding it has major consequences for many people.
Thanks to improving research, we now have a better idea of what people experience and how their condition progresses over time. https://ourworldindata.org/what-is-depression
Thiago Carvalho
boosted
1. "Language models generalize beyond natural proteins"
https://www.biorxiv.org/content/10.1101/2022.12.21.521521v1
They asked the question: can protein language models extend natural proteins and actually serve as an engine for generative design? The answer is seemingly yes.
Copied from: https://www.linkedin.com/in/elliot-hershberg
Thiago Carvalho
boosted
What an incredible man he is- to stay so calm in the face of such challenges. I had to fulfil my responsibility’: Fauci on his career, Covid and stepping down https://www.theguardian.com/us-news/2022/dec/25/fauci-interview-covid-trump-biden?CMP=Share_iOSApp_Other
'But even though the proliferation of wet-lab techniques and analytical methods has expanded access to single-cell studies, it has also muddied the waters for researchers trying to pick the best approach. The online single-cell RNA tools catalogue, scRNA-tools, lists nearly 1,400 software packages that turn single-cell data into scientific insights. How are researchers supposed to choose?'
'Here, we investigate the susceptibility of natural variants of the main protease (Mpro/3CLpro) of SARS-CoV-2 to protease inhibitors. Multiple single amino acid changes in Mpro confer resistance to nirmatrelvir (the active component of Paxlovid).'
Thiago Carvalho
boosted
There's going to be quite a lot to learn about the interactions between viral infections and susceptibility to Group A strep infections once we get through the current wave in 🇬🇧
#GAS #streptococcus #microbiology #IDMastodon
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00865-9/fulltext?dgcid=raven_jbs_aip_email#%20
Thiago Carvalho
boosted
The historic MBL Physiology Course is now accepting applications! If you're interested in learning more about the course and the application process, be sure to join us on Friday, January 13 at 9 AM PT for a virtual open house (https://berkeley.zoom.us/meeting/register/tJIlc-6gpjgjEt3OkOiHp6MCLgLm1HQiPOX6).
More info about the course is available here: https://www.mbl.edu/education/advanced-research-training-courses/course-offerings/physiology-modern-cell-biology-using-microscopic-biochemical-and-computational-approaches
'Inevitably, it raises a question about the purpose of biography. In reviewing the first volume of my own life of Keynes, the economist Maurice Peston wrote: ‘What help is knowledge of the lives of Newton and Einstein in predicting the movement of the planets?’ To which the answer is that economics is not a natural science like physics. One needs to know the economist, and his location in the flow of events, not to test his theories but to judge their value for our own time.'
Thiago Carvalho
boosted
All 23 of Timothy Snyder’s free lectures on “the Making of Modern Ukraine” are now posted. Millions of people have tuned in — everyone should listen to the whole course (they are also on Spotify).
https://podcasts.apple.com/us/podcast/the-making-of-modern-ukraine/id1653131950
#ukraine #podcast #history #yale #timothysnyder #highered #histodons @histodons
Thiago Carvalho
boosted
Study: #COVID19 vaccines have prevented more than 18 million additional hospitalizations and more than 3 million additional deaths in the United States
https://www.commonwealthfund.org/blog/2022/two-years-covid-vaccines-prevented-millions-deaths-hospitalizations #vaccines #vaccination #publichealth #epidemiology #healthcare
Thiago Carvalho
boosted
Nice RNA virus paper from earlier this year: Transcriptome Mining Expands Knowledge of RNA Viruses across the Plant Kingdom.
"these data highlight that ... the apparent scarcity of RNA viruses found in lower plants likely reflects a lack of investigation rather than their absence"
"In this work, we explored possibility of using drug-sensitivity data together with basal gene expression data on pancreatic cell lines to predict the combinatorial options available for HDACi and developed bioinformatics screening protocol for predictions of synergistic drug combinations in PDAC. "
Thiago Carvalho
boosted
Fission is in the news, but few recognize that a woman physicist was behind the discovery.
Lise Meitner’s brilliance led to the discovery of nuclear fission. But her long time collaborator Otto Hahn, was awarded the Nobel Prize in Chemistry w/o her in 1944, even though she had given the first theoretical explanation.
Albert Einstein called Meitner “our Marie Curie." She also adamantly refused to work on the atomic bomb during WWII. https://www.aps.org/publications/apsnews/201502/physicshistory.cfm #women #history #science #energy
Thiago Carvalho
boosted
Here’s one of my favourite artefacts: an ancient amber bear. Carved some 10,000 years ago, it washed up on a beach at Fanø in Denmark, from a submerged Mesolithic settlement.
On display National Museum of Denmark, Copenhagen. Read more about amber from submerged settlements: https://en.natmus.dk/historical-knowledge/denmark/prehistoric-period-until-1050-ad/the-mesolithic-period/magical-amber-animals/amber-from-submerged-settlements/
Thiago Carvalho
boosted
Staggering charts in the FT by John Burn-Murdoch show that after 12 years of Tory rule we are poorer, sicker and will die sooner than our peers. Utterly disgraceful.
Thiago Carvalho
boosted
The great Paulino Vieira, the genius of Cabo Verde music. Here, in an thrilling harp solo (1995, Paris). https://youtu.be/WfUARGzNqY0 via @YouTube
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
