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“Read not to contradict and confute; nor to believe and take for granted; nor to find talk and discourse; but to weigh and consider.”

Francis Bacon, born on this day in 1561, on learning and how to read intelligently themarginalian.org/2012/07/13/

RT @Bob_Fernandes
Ex-juiz, ex-ministro, ex-Catão, ex-herói verde amarelo, Moro paralisou a demarcação das Terras Indígenas e entregou a FUNAI para o que havia de pior. É um dos grandes responsáveis pela tragédia humanitária nas terras Yanomami.

You’re a postdoc in neuroscience, ecology or any field related to our research? Apply now and give a talk in our emerging scientist talk series! The talks will be held in our institute and you will have an opportunity to present and discuss your topic with our faculty and institute members. Travel and accommodation charges will be covered.
Apply by March 1st: bi.mpg.de/2599696/postdoc-semi

#mpiforbi #maxplanck #maxplanckinstitute #research #Science

#migration#re-Introduction.

I'm a theoretical neuroscientist at U Mainz Medical Center and co-affiliated with U Bonn Medical center. Primary focus on cortical circuits, their network activity, synaptic plasticity and protein dynamics in dendrites. Broadly interested how circuits learn e.g. neuro/AI interface and want to understand how neural networks compute, both algorithmically and intracellularly. Occational posts about societal and academic issues.

Kicking off 2023 with a celebration of #SciArt by @somedonkey 🎉​. This piece is featured as the current cover of @TrendsNeuro. Let me highlight what Julia has done here ...

The context is an article by myself and @amygdaloid arguing that what the brain does is complicated and difficult to describe. But it's also crucial to get these descriptions right, given that what we figure out about the brain rests on these definitions.

Julia brilliantly captures this complexity by embedding some wonderful illustrations in a larger piece depicting what we, as a field of brain researcher sleuths, are trying to do here.

First have a look at the whole and then let me give you a tour of some of its bits ...

made a drawing for
Joseph Le Doux’s 'Map of Your Mind' - Staged reading of a new musical at The Marsh, San Francisco

"Map of Your Mind illuminates the lives of four people in a therapy group for PTSD as they share their stories and strive to heal. The insights on memory and emotion are based on the work of co-writer and neuroscientist, Joseph Le Doux."

Playwright & Director: Lynne Kaufman, Co-writer, Lyricist, and Music: Joseph LeDoux

#themarshtheater #josephledeux #PTSD #lynnekaufman #illustration #blackandwhitedrawing #lineDrawing #albumart #juliakuhl #neuroscience #memory #therapy #mind #brain #map #mapofyourmind #musical #theater

'He had been a graduate student at the time, preparing the obligatory freshman survey course in the history of science, and trying to understand how anyone ever accepted Aristotelian physics. Kuhn vividly recalls gazing out of his window for some time before suddenly grasping that Aristotle had meant something very different by “motion” from his Newtonian successors.'

lareviewofbooks.org/article/co

Pets and AMR

"To date, most veterinary antimicrobial stewardship efforts have focused on food animal medicine, rather than companion animal medicine, since the largest volume of antimicrobials is used in animal agriculture. Importantly, however, studies increasingly recognize that resistant bacteria can be transmitted between companion animals, such as dogs and cats, and their human owners, and that pets can act as a reservoir for multidrug-resistant organisms that affect human health"


nature.com/articles/s41591-022

'My father had been born in the Austro-Hungarian Empire in April 1910. Few could have then foreseen the catastrophes to befall Europe over the next 35 years. This history is not irrelevant. It must serve as a warning. It has made me aware throughout my life that political mistakes can combine with economic disasters to unleash destruction upon societies believed civilised.'

ft.com/content/877d1a2d-67df-4

The bivalent booster in people age 65+ compared with those who did not receive it, among >622,000 participants
81% reduction of hospitalizations (Figure)
86% reduction of deaths
papers.ssrn.com/sol3/papers.cf

One difficult aspect of studying microorganisms on the molecular level is being able to fully understand the genetic connections and atomic structures involved.

This is especially so for viruses.

A trio of scientists have now made a full bacteriophage biomolecular model on the atomic scale for the first time ever.

How might this benefit future research, including antibiotic studies?

#Science #Virology #Biology #Viruses #Bacteriophage #sciencemastodon #scicomm

pubs.rsc.org/en/content/articl

Wow... just learned about this story on the race to invent optogenetics.

statnews.com/2016/09/01/optoge

The difference in doing and communicating high quality research from a "small" versus "elite" university is well amplified.

#neuroscience #optogenetics

it's always a good idea to revisit older posts in rich lenski's «telliamed»
"The Ten Commandments of Statistical Inference"
telliamedrevisited.wordpress.c via @RELenski

It’s not just EBV and MS, a number of viral infections are associated with increased risk for neural degenerative disease. Good reason to stay up-to-date on your flu and other vaccines. cell.com/neuron/fulltext/S0896

Scientists generally want their research to be openly accessible to the public.

So what's stopping them?

One study of Berkeley faculty (N = 479) found that 71% supported open access to research, yet only 18% of articles published by the group were open access.

"a journal having no cost to publish in was more important than having no cost to read"

via arl.org/wp-content/uploads/202
#OpenScience #Science #AcademicChatter #SciComm @academicchatter
h/t @oatp

'Because The Communist Manifesto has been so traduced and so feared, many people who haven’t yet read it think Marx’s polemic was either an instruction manual for overthrowing the government (Step 1, raid the police stations. Step 2, seize the post office, etc.) or wistful schematics for a society free of want and poverty.'

newrepublic.com/article/170065

One of the great privileges of creating the Darwin bicentennial exhibition with Jose Feijo was meeting incredible artists and artisans who developed pieces for the exhibition.

Elisabeth Daynes was one of them: she made our young Darwin (about the age he would have been when he came home from the voyage of the Beagle) by a painstaking process of forensic reconstruction, as described in this inset from the catalog that Filipa Vala and I wrote.

'We combine longitudinal repertoire sequencing data, stochastic evolutionary modeling, and tailored inference techniques to determine the characteristic time scales of T cell repertoire evolution. These timescales are in quantitative agreement with long tails observed in the distribution of clone sizes. We show that repertoire turnover slows down with age and is maximal in the largest clones of young individuals.'
Bensouda Koraichi et al @PNASNews

pnas.org/doi/10.1073/pnas.2207

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