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London calling.
---
RT @Raw_News1st
#MadridSeLevanta12F
Huge demonstration in Madrid. More than 250,000 people demonstrate to defend the public health system and protest against its privatization.
twitter.com/Raw_News1st/status

For the "every cell is an immune cell" files:

'In this Essay, we present fibroblasts as not only the builders and renovators of tissue environments but also the rheostat cells for immune circuits. Although they perform location-specific functions, they do not have badges of fixed identity'

journals.plos.org/plosbiology/

"Know less" seems generous:

'The Big Con of the book’s title is not a crime; it’s a confidence trick. Consultancies and outsourcers, Mazzucato argues, know less than they claim, cost more than they seem to, and — over the long term — prevent the public sector developing in-house capabilities.'

ft.com/content/fb1254dd-a011-4

Measuring antibodies in the murine central nervous system.

"In our study, we standardized a procedure and statistical analysis for a highly sensitive ELISA of a mouse Ab in mouse (C57BL/6J) CNS tissue."

journals.aai.org/jimmunol/arti

#Portugal : au moins 4 815 victimes de pédocriminalité dans l’Eglise depuis 1950 Plus de 500 témoignages ont été entendus par le groupe d’experts au cours de ce travail étalé sur environ un an. liberation.fr/international/eu

@academicchatter

Some good recent finds for #academics on mastodon. :)
- Mastodon Media List: docs.google.com/document/d/1TT list of Academic Journals and News Outlets.
- TrueSciPhi.org: truesciphi.org/ - Various comprehensive #science, #philosophy, and #mathematics lists covering podcasts, Mastodon, and Twitter.
- and of course: Academics on Mastodon - nathanlesage.github.io/academi

New from my Crick colleagues in @jpvincentlab: Ecdysone functions as a morphogen to control proliferation vs growth arrest in wing disc

Striking parallel with how bifunctional Gli proteins mediate Shh morphogen responses

biorxiv.org/content/biorxiv/ea

Interesting review about the role of sialic acids in interactions with gut microbes. Sialidases, transporters and metabolic enzymes particularly discussed.

tinyurl.com/2e6vsx78

"...reveals a previously unrealized pro-apoptotic function of the peptides generated by a variety of proteolysis-modulating compounds."
Constitutive protein degradation induces acute cell death via proteolysis products biorxiv.org/content/10.1101/20

Call for Nominations for SMBE’s prestigious Faculty Awards!

This is the time for our members to send us your recommendation of your favourite colleague for Early- or Mid-Career, Lifetime Achievement or special service to the EcoEvo community.

Details:
smbe.org/smbe/AWARDS/FacultyAw

EMBL-UNESCO Residency in Biology Research

'The successful candidate(s) will be hosted by one or more group leaders within the Infection Biology Transversal Theme, spread across EMBL’s six sites in Europe – who will mentor and co-develop the project proposed by the candidate, in line with the group’s research focus.'

embl.org/about/info/scientific

"When Twitter announced on 2 February that the social media platform would end free access to its application programming interface (API) in a week, meaning tomorrow, a clock began ticking for Jean-Philippe Cointet. Like other researchers interested in topics such as political polarization or how misinformation spreads, the social scientist at Sciences Po uses the API to freely gather data on the hundreds of millions of tweets sent daily."

science.org/content/article/tw

RT @mw_umn_labs
Excited to share our collaborative work with the @IngunnStromnes lab, out today in @NatureComms. Genome engineering and immunology join forces to create a powerful new model to study T cell development and function.

nature.com/articles/s41467-023

High quality research needs a supportive research environment. Our new paper in Nature Human Behaviour discusses how currently national academic systems fail to facilitate robust science.

Read it here: rdcu.be/c5brE

#OpenScience
#IchbinHanna
#Academic

The role of Evi/Wntless in exporting Wnt proteins

In their #OpenAccess Review, Lucie Wolf and Michael_Boutros summarise the mechanisms of Wnt ligand export and recent structural insights, with a focus on the Wnt transport protein Evi/Wntless.

journals.biologists.com/dev/ar

There’s no doubt that the UK has been a massive net beneficiary of the Horizon Europe programme for research funding.

Oxford and Cambridge alone used to receive an annual £130m of EU funding but are now down to £1m between them.

Brash declarations to ”go it alone” or form a coalition with the US, Switzerland and Japan show stunning disregard of how science works.

theguardian.com/politics/2023/

Now open for registration:

Cold Spring Harbor Asia:
Systems Biology of Gene Regulation and Genome Editing

Suzhou, China
October 23 - October 27, 2023

csh-asia.org/?content/333

#genomics #CSHL #CSHLAsia #GeneRegulation #GenomeEditing

'Back in Aix, his discussion circle had included not only Émile Zola, on a fast track to celebrity, but a formidable young scientist called Antoine-Fortuné Marion. It was Marion who alerted the group to the recent revolutions in thought advanced by Lyell and Darwin. Zola articulated their response in 1865: ‘I see in the study of geology a new faith, a faith both philosophical and religious.’'

lrb.co.uk/the-paper/v45/n04/ju

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