Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Gerhard Richter, Untitled from Canary Landscapes (Kanarische Landschaften), 1970–71 #museumarchive #museumofmodernart http://www.moma.org/collection/works/66509
"Smith was first and foremost an Enlightenment thinker who sought to empower humanity to reshape and reimagine the world. The utopian rigor of market thought would have cut against his entire method and approach to social and economic life—especially his democratic sensibilities, his feeling that there was no single order that could be imposed on all of society."
"Because of the important role of the ENS in controlling intestinal functions, it is not surprising that changes in ENS development and function are connected to intestinal microbiota dysbiosis in various human disorders"
https://journals.physiology.org/doi/full/10.1152/ajpgi.00166.2022
Thiago Carvalho
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RT @CyrilPedia
My latest Clinical Pipeline column is out, a look at an anti-FcRn monoclonal for severe hemolytic disease of the fetus and newborn https://twitter.com/NatureMedicine/status/1630906381376135169
Thiago Carvalho
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Online now: Can herbivores sharing the same host plant be mutualists? https://www.cell.com/trends/ecology-evolution/fulltext/S0169-5347(23)00026-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
The Torremolinos model of human evolution:
"Like retirees who flock to the Costa del Sol, ancient European hunter-gatherers sought out Spain’s warmer climate during the peak of the last ice age."
'Here, we investigated the generality, specificity and mechanistic basis of immune priming in the fruit fly Drosophila melanogaster when infected with the gram-negative bacterial pathogen Providencia rettgeri.'
Thiago Carvalho
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PNAS outlines its policy for the use of text generated by ChatGPT et al in papers. Not clear what the process will be if the AI is an Academy Member.
https://www.pnas.org/post/update/pnas-policy-for-chatgpt-generative-ai
Thiago Carvalho
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Last fall I spoke with @MarkHanson, who was then in Bruno Lemaitre's lab, for EMBO's @ReviewCommons platform for refereed #preprints. I love this detail about how flies grow - I picture a tiny little bicycle pump in there somewhere:
'When flies eclode from the pupa they are soft and squishy and they “manually” inflate their wings by pumping air through their body and that inflates the cuticle in a way that there is room for the body to move around inside that shell.'
#Drosophila #InnateImmunity
https://www.reviewcommons.org/blog/models-oddballs-and-preprints-a-conversation-with-mark-hanson/
Thiago Carvalho
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Enter the Red Queen.
"Eric Mitchell, a graduate student at Stanford University, figured a classifier would take a lot of training data. Along with colleagues, he came up with DetectGPT, a “zero-shot” approach to spotting the difference, meaning the method requires no prior learning. Instead, the method turns a chatbot on itself, to sniff out its own output."
https://www.ft.com/content/e34c24f6-1159-4b88-8d92-a4bda685a73c
Thiago Carvalho
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'Because mink are known to spread certain viruses to humans, the fear was that the disease could jump from mink to people. No humans got sick from the outbreak in Spain, but other infections have spread from mink to humans before: In 2020, COVID outbreaks on Danish mink farms led to new mink-related variants that spread to a small number of humans.'
https://www.theatlantic.com/health/archive/2023/02/mink-farm-bird-flu-virus-infection-spread/673236/
Thiago Carvalho
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Online now - our 2023 issue 5:
Activation of #plant #NLR #immune receptors
#Stereoisomer specificity in #flagellin #sialylation
Dormant #ribosome activation by #TORC1
#Cytomegaloviral #DCAF for #cullin-mediated #STAT2 degradation
Cover: Korolchuk lab
https://www.embopress.org/toc/14602075/2023/42/5
"But the oldest DNA of modern humans in Europe, dating back 45,000 years, undermines such a simple story. It comes from people who belonged to a lost branch of the human family tree. Their ancestors were part of the expansion out of Africa, but they split off on their own before the ancestors of living Europeans and Asians split apart."
https://www.nytimes.com/2023/03/01/science/dna-hunter-gatherers-europe.html
Thiago Carvalho
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Have 5 minutes? Then you have time to support preprints! ⏲️
PDF version: https://buff.ly/3KKqGTF
Thiago Carvalho
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Rosalind Franklin, born in 1920, was a British chemist whose contributions were vital to the discovery of the structure of DNA. Her work led to the Nobel Prize being awarded to two men, Watson and Crick, who allegedly stole her work and never acknowledged her contribution. #WomensHistoryMonth
Thiago Carvalho
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Great news: #EliLilly caps the price of #insulin at $35 a month. #diabetes #medicine https://www.nbcnews.com/health/health-news/eli-lilly-caps-cost-insulin-35-month-rcna72713
"The neonatal Fc receptor and the planet Neptune share the distinction of having had their existence predicted by theoretical models before they were discovered."
My latest Clinical Pipeline column at Nature Medicine is out.
Thiago Carvalho
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March 1, 1833, the HMS Beagle ⛵ arrives at the Falkland Islands, where #Darwin geologizes a bit and collects fossils ⚒ like those brachiopods.
Thiago Carvalho
boosted
Thiago Carvalho
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Sounds exciting.
"...positive feedback between cell state and signalling pattern regulates the long-range signal coding that drives morphogenesis."
Controlling periodic long-range signalling to drive a morphogenetic transition https://doi.org/10.7554/eLife.83796
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
