Thiago Carvalho @cyrilpedia@social.cleverlibre.org

This is just a ludicrous policy. Think of it this way: what would happen if Australia, Japan, South Africa or India asked for the lab notebooks of American researchers every three months? This is ill-considered policy, which will dissuade global health research. This is on NIH and HHS. They put this in place. They need to fix it.

https://www.nature.com/articles/d41586-023-01930-0

@halama_immuno @physorg_bot @gpollara Absolutely - but there are some very interesting details here, like this one "For instance, we find that bats have either lost CARD8 or have a CARD8 protein that is antagonized, rather than activated, by coronavirus 3CLpro cleavage."

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002144

June 9, 1891, French painter Paul Gauguin arrives in Papeete, Tahiti - a landscape of Tahiti with #volcano 🌋🖌️

"As of January 2023, the estimated prevalence of long Covid among people in the United States who had had acute infection was 11%. According to guidance released in August 2021 by the Department of Health and Human Services and the Department of Justice, long Covid can be considered a protected disability under the Americans with Disabilities Act (ADA) and under other disability-antidiscrimination mandates (such as Section 504 of the Rehabilitation Act and Section 1557 of the Affordable Care Act)."

#covid #longcovid #covid19

https://www.nejm.org/doi/full/10.1056/NEJMp2302676?query=featured_home

My Clinical Pipeline column for Nature Medicine this week examines the state of Sarepta's new gene therapy for Duchenne muscular dystrophy application at the FDA. Whatever its final efficacy turns out to be, the general strategy behind the therapy, an engineered micro-dystrophin is very clever.

It was inspired by the case of a 61 year old patient who had a deletion of almost half of his dystrophin gene and was still alive and walking. Here's that ref, from 1990:
https://www.nature.com/articles/343180a0

And here's my column:

https://www.nature.com/articles/d41591-023-00052-4

@physorg_bot This trip-wire has been around for awhile already... @gpollara @cyrilpedia

Referenced link: https://medicalxpress.com/news/2023-06-immune-wire-covid-.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-immune-wire-covid-.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1666867708095234049#m

RT by @physorg_com: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://journals.plos.org/plosbiology/article https://medicalxpress.com/news/2023-06-immune-wire-covid-.html

'These biofilms encase immune cells and establish a high local concentration of a secreted hemolysin to kill the immune cells before the biofilms disperse in a c-di-GMP-dependent manner.'

https://www.cell.com/cell/fulltext/S0092-8674(23)00527-5

Large scale proteomic studies create novel privacy considerations | https://www.nature.com/articles/s41598-023-34866-6#additional-information #proteomics

The US Supreme Court is a farce. It should no longer be supreme.
"The US Supreme Court has gutted federal protection for wetlands — now what?"

https://www.nature.com/articles/d41586-023-01827-y?

As CSHL is the home of
@biorxivpreprint, I've put together a @preLights 'preList' of #preprints mentioned during #cshlsymp23:

https://prelights.biologists.com/prelists/cshl-87th-symposium-stem-cells/

We’re looking for African researchers keen to represent their community on our editorial board.

Does this sound like you? Apply to join our Board of Reviewing Editors! https://elifesciences.org/inside-elife/5b024d5b/elife-latest-applications-open-for-new-reviewing-editors-in-africa?utm_source=mastodon&utm_medium=social&utm_campaign=organic

This is outrageous. Spread the word. Are you a US researcher working w foreign institutions? There is something awful brewing: "For foreign subrecipients, the subrecipient to provide copies of all lab notebooks, all data, all documentation that supports the research outcomes as described in the progress report. These supporting materials must be provided to prime recipient with each scientific update (no less than once every six months, or more frequently based on risks). https://rfi.grants.nih.gov/?s=646e6654a8ba09024f09e852

One thousand samples per day capillary-flow LC/MS/MS for high-speed, high-sensitivity and in-depth proteomics | https://www.biorxiv.org/content/10.1101/2023.06.05.543682v1.full.pdf+html #proteomics