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'While extensive research has focused on mitochondrial dNTP homeostasis due to its defects being associated with various mitochondrial DNA (mtDNA) depletion and deletion syndromes, the investigation of mitochondrial rNTP homeostasis has received relatively little attention.'

embopress.org/doi/full/10.1525

Steer clear of steatosis – VEGFA lipid nanoparticles (LNPs) drive BEC-hepatocyte conversion, an alternative pathway for liver regeneration. #Gouon-EvansLab

Wonderful preLight written by Sakurako Kobayashi and Ryan Brown. They will coordinate more #preprint highlights from the Organogenesis and Cancer Program #PeterMacCC 💡📝

#preLight 👉 prelights.biologists.com/highl

#liver, #regeneration, #mice, #zebrafish

Anyway, Tom’s article is a fascinating read that relates changes in science to broader changes in academia.

And before you go, here’s another of Tom’s recent contributions you might find interesting: “The Invisible Workload of Open Research”: doi.org/10.36850/mr5

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How does the science reform movement align with broader changes in the academic landscape? Tom Hostler tackles this question in a new article on “Scientific reform, post-academic research, and academic identity”: markrubin.substack.com/p/scien
🧵👇

#OpenScience
#MetaScience
#MetaResearch
#ReplicationCrisis
#SociologyofScience
#ScienceofScience
#STS
@stsing

"This series consists of three-dimensional and collapsable (pop-up) collages, made inside cardboard boxes. The images used are engravings and illustrations found in a german encyclopedia published in the 1930’s.
Scales range from 15cmx21cm to 21x28cm."

madalenaparreira.com/Collages

Malpighian tubules are one of the most successful organs on earth 🌏 🌍 🌎

The majority of animals have them. Doesn't matter: biomass? total species? total population? Got 'em.
🐕 🐛 🐦🐜🐞 🐟 🦋🐜🕷️🙆 🐜

What I'm saying is: not having malpighian tubules is *peak* counterculture ✊✊✊

What can you expect from one of our Open Days?

Join students Michael and Chan as they take you to an Open Day at Imperial College London 🔍

youtu.be/5z_YYH3h0jU

'Meta has axed a team that used artificial intelligence to create the first database of more than 600mn protein structures, in a signal the company is abandoning purely scientific projects in favour of building moneymaking AI products.'

ft.com/content/919c05d2-b894-4

“We’re used to hurricanes ruining plans, tropical storms, even just bad thunderstorms,” she said. “But I don’t recall ever looking at anyone and saying ‘It’s too hot to go to the beach.’”
nytimes.com/2023/08/05/travel/

In the largest study to measure cytokines and chemokines during Covid, with or without vaccination, a lower inflammatory profile was seen with prior vaccination, supporting its potential short and long- term protective benefit
thelancet.com/journals/lanmic/

1985 | Franz Hillenkamp and his colleague Michael Karas used a LAMMA 1000 mass spectrometer to demonstrate the technique of matrix-assisted laser desorption/ionization (MALDI) | #proteomics

Douglas Adams: "The major problem—one of the major problems, for there are several—one of the many major problems with governing people is that of whom you get to do it; or rather of who manages to get people to let them do it to them.
To summarize: it is a well-known fact that those people who must want to rule people are, ipso facto, those least suited to do it.
To summarize the summary: anyone who is capable of getting themselves made President should on no account be allowed to do the job."

A reminder to submit your symposium proposal for the 3rd Joint Congress on Evolutionary Biology, to be held in Montreal in July 2024. The Joint Congress will bring together researchers from the European Society for Evolutionary Biology, the Society for the Study of Evolution, the American Society of Naturalists, and the Society of Systematic Biologists. (1/2)

Every time I write about the dangers of pickup trucks, I get attacked in hundreds of tweets and comments as a leftist looney. I hope it is more civil on Mastodon! But it is past time they were regulated, particularly in cities. lloydalter.substack.com/p/its-

Mary Frances Winston Newson was born #OTD in 1869.

She became the first female American to receive a PhD in mathematics from a European university, namely the University of Göttingen in Germany. She was also the first person to translate Hilbert's problems into English.

Hilbert put forth a most influential list of 23 unsolved problems at the International Congress of Mathematicians in Paris in 1900. via @wikipedia

#books #mathematics

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