'While extensive research has focused on mitochondrial dNTP homeostasis due to its defects being associated with various mitochondrial DNA (mtDNA) depletion and deletion syndromes, the investigation of mitochondrial rNTP homeostasis has received relatively little attention.'
#mitochondria
“The idea that the poor should have leisure has always been shocking to the rich.” https://www.theguardian.com/commentisfree/2023/aug/08/britain-poor-people-leisure-victorian-workhouse
Calcium and bicarbonate signalling pathways have pivotal, resonating roles in matching ATP production to demand. https://elifesciences.org/articles/84204?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Steer clear of steatosis – VEGFA lipid nanoparticles (LNPs) drive BEC-hepatocyte conversion, an alternative pathway for liver regeneration. #Gouon-EvansLab
Wonderful preLight written by Sakurako Kobayashi and Ryan Brown. They will coordinate more #preprint highlights from the Organogenesis and Cancer Program #PeterMacCC 💡📝
#preLight 👉 https://prelights.biologists.com/highlights/vegfa-mrna-lnp-promotes-biliary-epithelial-cell-to-hepatocyte-conversion-in-acute-and-chronic-liver-diseases-and-reverses-steatosis-and-fibrosis/
Anyway, Tom’s article is a fascinating read that relates changes in science to broader changes in academia.
And before you go, here’s another of Tom’s recent contributions you might find interesting: “The Invisible Workload of Open Research”: https://doi.org/10.36850/mr5
How does the science reform movement align with broader changes in the academic landscape? Tom Hostler tackles this question in a new article on “Scientific reform, post-academic research, and academic identity”: https://markrubin.substack.com/p/scientific-reform-post-academic-research
🧵👇
#OpenScience
#MetaScience
#MetaResearch
#ReplicationCrisis
#SociologyofScience
#ScienceofScience
#STS
@stsing
"This series consists of three-dimensional and collapsable (pop-up) collages, made inside cardboard boxes. The images used are engravings and illustrations found in a german encyclopedia published in the 1930’s.
Scales range from 15cmx21cm to 21x28cm."
New SARS-CoV-2 variant gains dominance in US amid mild summer COVID wave https://arstechnica.com/?p=1959483
What can you expect from one of our Open Days?
Join students Michael and Chan as they take you to an Open Day at Imperial College London 🔍
#IDMastodon #Immunology Oview & Understanding of sex differences in #immunometabolism #viralinfections ( #SarsCoV2 ) prophylaxis and therapy
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1259382/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FIMMU_XXXXXXXX_auto-dlvrit
'Meta has axed a team that used artificial intelligence to create the first database of more than 600mn protein structures, in a signal the company is abandoning purely scientific projects in favour of building moneymaking AI products.'
https://www.ft.com/content/919c05d2-b894-4812-aa1a-dd2ab6de794a
“We’re used to hurricanes ruining plans, tropical storms, even just bad thunderstorms,” she said. “But I don’t recall ever looking at anyone and saying ‘It’s too hot to go to the beach.’”
https://www.nytimes.com/2023/08/05/travel/summer-travel-climate-change.html
In the largest study to measure cytokines and chemokines during Covid, with or without vaccination, a lower inflammatory profile was seen with prior vaccination, supporting its potential short and long- term protective benefit
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00171-4/fulltext
1985 | Franz Hillenkamp and his colleague Michael Karas used a LAMMA 1000 mass spectrometer to demonstrate the technique of matrix-assisted laser desorption/ionization (MALDI) | #proteomics
Douglas Adams: "The major problem—one of the major problems, for there are several—one of the many major problems with governing people is that of whom you get to do it; or rather of who manages to get people to let them do it to them.
To summarize: it is a well-known fact that those people who must want to rule people are, ipso facto, those least suited to do it.
To summarize the summary: anyone who is capable of getting themselves made President should on no account be allowed to do the job."
A reminder to submit your symposium proposal for the 3rd Joint Congress on Evolutionary Biology, to be held in Montreal in July 2024. The Joint Congress will bring together researchers from the European Society for Evolutionary Biology, the Society for the Study of Evolution, the American Society of Naturalists, and the Society of Systematic Biologists. (1/2)
“Watch the Making of Japanese Woodblock Prints, from Start to Finish, by a Longtime Tokyo Printmaker” https://www.openculture.com/2020/11/watch-the-making-of-japanese-woodblock-prints-from-start-to-finish.html
Every time I write about the dangers of pickup trucks, I get attacked in hundreds of tweets and comments as a leftist looney. I hope it is more civil on Mastodon! But it is past time they were regulated, particularly in cities. https://lloydalter.substack.com/p/its-time-for-limits-on-truck-and
Mary Frances Winston Newson was born #OTD in 1869.
She became the first female American to receive a PhD in mathematics from a European university, namely the University of Göttingen in Germany. She was also the first person to translate Hilbert's problems into English.
Hilbert put forth a most influential list of 23 unsolved problems at the International Congress of Mathematicians in Paris in 1900. via @wikipedia
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com