Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'A recently identified autoimmune disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic (VEXAS) provides insight into the synergistic effects of genetic perturbations and stress responses leading to autoinflammation.'
Butera et al @EmboMolMed
Thiago Carvalho
boosted
Republicans won’t fight for kids to get school lunch but they’ll fight to make them have a baby? Fuck you, GOP.
Thiago Carvalho
boosted
Did you know my free online textbook comes with 140 interactive practice questions for your students to test their understanding of p-values, Type 1 and 2 errors, effect sizes, confidence intervals, sample size justification, etc? https://lakens.github.io/statistical_inferences/01-pvalue.html#test-yourself
Thiago Carvalho
boosted
Funny how historical #UFOs always look exactly like human design objects from the period in which they were photographed...
Early-mid- 20th century UFOs all look like Art Deco Bakelite.
Oh, and they have aerials on top because that was the human technology of the day.
As the Beatles would suggest, come together, right now.
"Research on the origin and early evolution of life therefore comprises two areas of understanding that in practice make little contact with one another (Fig. 1). We understand some of the chemistry and geochemical settings that could have led to an origin of life and we can also infer details about early organisms through the most ancient protein families. In practice, however, these two fields of research remain largely disconnected."
Thiago Carvalho
boosted
'Fifty years ago this month, the best-selling novel and the best-selling nonfiction title in the country had something unusual in common: They were both illustrated.'
https://www.nytimes.com/2023/08/10/books/review/joy-of-sex-breakfast-of-champions.html
Thiago Carvalho
boosted
"Fazer plantações da mesma casta mas com clones misturados aumenta a estabilidade de comportamento da vinha. Estamos a aumentar a capacidade da videira de amortecer variações [climáticas]", explica Graça.'
Thiago Carvalho
boosted
'We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen-presenting cells (tumor-APCs). Enforced expression of the transcription factors PU.1, IRF8, and BATF3 (PIB) was sufficient to induce the cDC1 phenotype in 36 cell lines derived from human and mouse hematological and solid tumors.'
"If justice is blind, she sometimes heads down unpredictable paths. For example, only in Donald Trump’s fourth felony indictment, unsealed last night in Atlanta, has a local prosecutor managed to deliver a sweeping, nationwide view of the former president’s scheme to steal the 2020 election."
https://www.theatlantic.com/ideas/archive/2023/08/trump-georgia-indictment-election/675018/
Thiago Carvalho
boosted
Flights serving the eastern Sicilian city of Catania were halted after an eruption from nearby Mount Etna, local authorities said, bringing fresh travel troubles to the crisis-plagued Italian airport.
Catania’s mayor has banned the use of motorcycles and bikes while many streets in the city remain covered by ash as a result of the erupting volcano.
It positively glows with marital bliss
"Yet Jakob Fugger and Sybilla Artzt were man and wife. This painting, by the German artist Hans Burgkmair the Elder, was made to commemorate their wedding in 1498."
https://www.ft.com/content/3dbc2126-04eb-4b42-90ca-df5f39399f58
Thiago Carvalho
boosted
Do you see power lines (or cable tv or internet fiber) hanging above ground in Europe? No, they are buried, especially near human populations and where there is fire risk. Only high voltage transmission towers near production facilities are seen above ground. But those are designed to withstand high winds, earthquakes, and such---unlike the ancient "technology" of wooden poles barely lifting old cables used by American utilities. It is only the insularity of the USA, including reporting in media such as this article, that prevents the population from understanding that other countries have fixed this problem. It just takes investment from the utility companies to bury the cable and avoid such unnecessary and recurrent tragedy.
Experts Scrutinize Hawaiian Electric as They Search for the Maui Wildfire Cause https://www.nytimes.com/2023/08/14/us/hawaiian-electric-maui-wildfire.html?smid=nytcore-android-share
Thiago Carvalho
boosted
Boss of water company behind major beach sewage leak handed 65% bonus boost https://www.thelondoneconomic.com/business-economics/boss-of-water-company-behind-major-beach-sewage-leak-handed-65-bonus-boost-354594/
“He could actually read a room and understand how to make it a meaningful experience,” says Hesse, recalling that 1966 Monterey jazz festival performance. “From the first note, he had the people in the palm of his hand and then took them on a journey throughout the entire set.”
Thiago Carvalho
boosted
In my mind, broadly compatible that faster viral clearance with #COVID19 #vaccination 👉 less antigen 👉 lower inflammatory response.
Further supports hypothesis that #vaccine works by dampening excessive #inflammation to #SarsCoV2, which drives severe disease.
#Immunology
Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study - The Lancet Microbe
Thiago Carvalho
boosted
Environmental Scientist: Climate Risk and Resilience
GHD Group
See the full job description on jobRxiv: https://jobrxiv.org/job/environmental-scientist-climate-risk-and-resilience/?feed_id=55126
#ScienceJobs #hiring #research
Suva #Fiji #Researcher #Scientist
https://jobrxiv.org/job/environmental-scientist-climate-risk-and-resilience/?feed_id=55126
'We have identified a neural circuit for innate male sexual behavior (Figure 7U). This circuit enables recognition of potential mates and motor displays of mating, rejuvenates sexual drive, and makes mating rewarding. Moreover, our findings show that the brain employs distinct neural circuits to generate male mating and aggression.'
#Neuroscience
https://www.cell.com/cell/fulltext/S0092-8674(23)00798-5#gr7
Thiago Carvalho
boosted
Missing the point
Yes taxation rates matter. But France-Spain and France-Belgium trains are expensive to take *because the capacity is too low*
If you reduce ticket prices on those routes you WON’T TRANSPORT MORE PEOPLE. Just different people. As the trains are full anyway
So, Clement Beaune, how are you going to get more TGVs to Barcelona?
Thiago Carvalho
boosted
Cancer, and Wolf?
Causes of death in London, 1632.
h/t Very British Problems
'The administrative dissolution of groups suspected of antistate violence, the ultimate political weapon in the government’s arsenal, had until recently been used primarily against Islamic terrorists and neofascist groups. Now it is being deployed against ecological activists.'
https://www.nybooks.com/online/2023/08/13/the-war-of-the-worlds-in-france/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
