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'Consistently, these bans target materials written by and about people of color or LGBTQ+ individuals, and even though a 2022 poll found that 70% of parents oppose them, they are continuing at a rapid rate.

Now the Digital Public Library of America (DPLA) is trying to fight back. It recently launched the Banned Book Program, granting free nationwide access to books restricted in schools or libraries.'

theguardian.com/us-news/2023/a

"Even more concerning is the idea that content produced by generative AI is polluting the data sets on which future systems will be trained, threatening what some have called “model collapse”. By adding more imperfect information and deliberate disinformation to our knowledge base, generative AI systems are producing a further “enshittification” of the internet, to use Cory Doctorow’s evocative term. This means training sets will spew out more nonsense, rather than less."

ft.com/content/ed323f48-fe86-4

'Specific deletion of the nuclear isoform of RARα revealed an RARα isoform in the cytoplasm of T cells. Extranuclear RARα was rapidly phosphorylated upon TCR stimulation and recruited to the TCR signalosome.'

cell.com/immunity/fulltext/S10

'Alas, the results of most longevity studies are difficult to compare. This is in part because there are no clear, universally accepted standards for conducting such experiments or even for reporting such data.'

biorxiv.org/content/10.1101/20

'In different ways, political philosophers, economists and advertising executives have pointed out how our economic system capitalizes on the insecurities it produces, which it then prods and perpetuates, making us all insecure by design. Only by reckoning with how deep manufactured insecurity runs will it become possible to envision something different.'

nytimes.com/2023/08/18/opinion

This is great: you type your zip code into the app, and you're shown a complete list of books prohibited in your area; then download the e-reader, and these books are available to download.

theguardian.com/us-news/2023/a

I wonder if the book-banners will end up making these books more widely read than they ever were in libraries?

'Genome sequencing has also become a critical component in the development of one of the most promising alternatives to antibiotics: bacteriophage therapy.'

journals.plos.org/plosbiology/

'Our much loved Microbe Art Contest is coming back again this year to support International Microorganism Day on 17 September 2023! Help celebrate the wondrous world of microbes by getting creative and sharing your art! '

fems-microbiology.org/microbe-

'Here, we report the T1D Knowledge Portal (T1DKP), an open-access resource developed to help advance T1D research by democratizing access to genetic, genomic, and epigenomic data.'

journals.plos.org/plosbiology/

The interplay between lumen pressure and cell proliferation determines organoid morphology in a multicellular phase field model biorxiv.org/content/10.1101/20

In the end the best results were obtained using an ALFA tag labeled with primary and secondary antibodies, or a triple ALFA tag with an anti-ALFA PAINT nanobody. In both cases, we could visualize the actin mesh, rails and corrals in tagged presynapses! 20/23

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Assistant Professors of Neuroscience

Johns Hopkins University

Johns Hopkins University is currently accepting applications for six tenure-track Assistant Professor positions in neuroscience-related fields

See the full job description on jobRxiv: jobrxiv.org/job/johns-hopkins-

#ScienceJobs #hiring #research ...
jobrxiv.org/job/johns-hopkins-

Subset of neurons in #hypothalamus increases appetite & decreases #thermogenesis. @JongSohn &co show that ion channel GIRK2 functions in hypothalamic NPY/AgRP neurons to increase energy expenditure in mice and may control body weight @kaistpr #PLOSBiology plos.io/3qGa8Ev

Just published
When a nasal vaccine provides superior immune response compared with a shot (2 doses of each). Results from a randomized clinical trial, including vs Omicron, and with less local and systemic adverse effects
nature.com/articles/s41541-023

Reading:

Viome, a microbiome startup, raises $86.5M, inks distribution deal with CVS tcrn.ch/47zUkDY

Which quotes me a bit. Needless to say, I am very skeptical of Viome and many of its claims.

#EMT is an early event in cell dissemination from epithelial tissues. @EricTheveneau &co show that in frog embryos the #metalloproteinase MMP28 is produced by placodes & acts inside the nucleus of neighboring neural crest cells to trigger EMT #PLOSBiology plos.io/3snRL7F

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