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Interested to hear views on the value/danger of mandating institute-wide common digital lab notebook tech

Problems I can see:

- complexity is important for some groups, but gives intolerably steep learning curve for groups who host short-term researchers.

- Tie-in to a commercial ecosystem that might degrade or raise costs. DIY options (as championed by @steveroyle) therefore ideal for some groups, but not not feasible for others.

Pros: SOPs. Am doubtful about the value of this, am I wrong?

"Despite what politicians say, Europeans have become more welcoming to people fleeing humanitarian crises."

nature.com/articles/d41586-023

Trenitalia eyes up the Paris-Brussels-Amsterdam route, currently only served by Thalys (they're also considering Paris-Barcelona, in competition with SNCF & potentially Renfe) ft.com/content/7ccb3037-64f8-4

"From a genomic perspective, the majority of post-Black Death strains of Yersinia pestis thus far identified in Europe display diversity accumulated over a period of centuries that form a terminal sub-branch of the Y. pestis phylogeny. It has been debated if these strains arose from local evolution of Y. pestis or if the disease was repeatedly reintroduced from an external source."

journals.plos.org/plospathogen

'Se aprofundarmos e detalharmos a informação disponível, temos que 66% dos trabalhadores ganham abaixo dos 1000 euros mensais e 27% ganham entre 1000 e 2499 euros. Apenas 4% ganham entre 2500 e 4999 euros. Acima dessa remuneração, estão apenas 0,7% dos trabalhadores.'

publico.pt/2023/08/18/opiniao/

From heat waves and wildfires to downpours and flooding, 2023 has given us a taste of the impacts we can expect over the coming decades and centuries.

Without very significant reductions in greenhouse gases—beginning immediately—it is very likely that global surface temperatures will exceed the 1.5C threshold set in the 2015 Paris climate agreement.

10 facts that prove the world is in a climate emergency.

wired.co.uk/article/climate-ch

#ClimateChange #Heatwaves #Wildfires #Floods #GreenhouseGas

Inexcusable.

"The UN has backed a Home Office-funded pilot that would dramatically reduce the spiralling costs of the crisis-hit asylum system – yet Suella Braverman is refusing to endorse the scheme, despite it being described as 'more humane'."

theguardian.com/world/2023/aug

🇪🇸 Spain COVID: Mask mandates reinstated in Barcelona hospital.

The Hospital Clínic de Barcelona ​will make mask wearing compulsory again in the emergency unit and for visitors due to the rebound in covid cases.

#COVID19 #Spain @auscovid19 #COVIDisAirborne #COVIDIsNotOver

Source: lavanguardia.com/vida/20230818

Charles Darwin first publishes his theory of evolution through natural selection in The Journal of the Proceedings of the Linnean Society of London, alongside Alfred Russel Wallace's same theory #OTD in 1858.

Darwin emphasised competition between individuals of the same species to survive & reproduce, whereas Wallace emphasised environmental pressures on varieties & species forcing them to become adapted to their local conditions, leading populations in different locations to diverge.
#science

"Humanity has a decision to make. We stand today at the brink of a new age, at a fork in the road of our own survival. We can become another extinct species, a blink in time in the natural history of the earth, or we can recognize that water is so vital to our continued existence that we must find a new way to live with it, manage it, and protect it."

The Three Ages of Water, Peter Gleick, Hachette, 2023
hachettebookgroup.com/titles/p

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A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release. elifesciences.org/articles/905

Sure would be swell if #government could spin up some internal #Mastodon instances for alerts, weather notifications, public safety announcements, and public statements...

Just sayin...

#Fediverse #weather #climate #ClimateChange

"Within the confines of the traditional clinical research model, studying novel treatments for rare cancer subtypes is challenging — particularly with respect to patient engagement, financial burden and timeliness. In this issue of Nature Medicine, Liu et al. describe a novel trial design that positions the patient at the focal point of clinical investigation, while exploring the safety and efficacy of first-line pyrotinib in patients with metastatic HER2+ NSCLC"

nature.com/articles/s41591-023

Meanwhile, in Portugal, one cant go to Madrid by train anymore & all the ruling parties debate is where to put a new airport.

"The Italian state-owned train operator is aiming to launch high-speed rail services between some of Europe’s biggest cities as it takes advantage of the liberalisation of the region’s network."

ft.com/content/7ccb3037-64f8-4

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