Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
“America is entering its most important, pivotal year since 1860, and the U.S. media is doing a terrible job explaining what is actually happening.…
What we call the Republican Party is barely a political party in any sense of the word but a dangerous antisocial movement that has embraced many of the tenets of fascism, from calls for violence to its dehumanizing of ‘others.’”
Must read @willbunch
https://www.inquirer.com/opinion/commentary/media-2020-election-trump-authoritarianism-20230827.html https://www.inquirer.com/opinion/commentary/media-2020-election-trump-authoritarianism-20230827.html#loaded
Thiago Carvalho
boosted
Science Operations Manager
University of Washington
See the full job description on jobRxiv: https://jobrxiv.org/job/science-operations-manager/?feed_id=56910
#ScienceJobs #hiring #research
Seattle #UnitedStatesUS #Manager
https://jobrxiv.org/job/science-operations-manager/?feed_id=56910
Thiago Carvalho
boosted
10 years, 500 scientists, and €600 million, and now the Human Brain Project — one of the biggest research endeavours ever funded by the European Union — is coming to an end. How did it go?
#HumanBrainProject
Thiago Carvalho
boosted
Introducing Neuropixels Ultra, a new probe with >10x site density: an implantable voltage camera capturing complete planar images of neurons' electrical fields in vivo! ⬆️ spike sorting yield, ⬆️ detection of small fields, and ⬆️ cell type identification.🧵
https://www.biorxiv.org/content/10.1101/2023.08.23.554527
Thiago Carvalho
boosted
🏳️🌈🖖🏽
White supremacy, racially motivated hate crimes, and the murders of racial, religious and sexual minorities don’t happen in a vacuum. They are encouraged, given life, and ultimately driven by leaders who knowingly deploy the terror to advance and increase their own power.
Thiago Carvalho
boosted
You can join the Alliance of World Scientists by becoming a signatory on the paper that declared a climate emergency (https://academic.oup.com/bioscience/article/70/1/8/5610806), with 26k other scientists: https://scientistswarning.forestry.oregonstate.edu/join_AWS #ClimateChange
Thiago Carvalho
boosted
Wrote something for the Guardian about cancer screening today - for those with (undiagnosed) cancer it can save their life. But if vast majority of people screened *don't* have cancer, then it can also strain NHS resources and lead to some people being diagnosed (and worse, treated for) a cancer they do not have.
Increases in screening must come with transparent information & plan for how NHS will deliver it.
Thiago Carvalho
boosted
New chapter in our ongoing RNA Review Series:
Javier Caceres and colleagues discuss #mRNA quality control mechanisms including non-stop and no-go mRNA decay pathways and the nonsense-mediated mRNA decay pathway
Translation-coupled mRNA quality control mechanisms
https://www.embopress.org/doi/full/10.15252/embj.2023114378
'While Aβ is clearly the initiating factor in the context of mutations in the genes encoding APP and, likely, presenilin 1 and presenilin 2, I propose that accumulation of pathogenic forms of tau is not a consequence of Aβ in all cases of sporadic AD'
#alzheimers #alzheimersdisease
https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(23)00166-2
Thiago Carvalho
boosted
Public #OpenScience lecture by Prof Felix Schoenbrodt @nicebread, managing director of the @lmu_osc, on the replicability crisis for #OSCSummerSchool23
📅11.09. at 10:00 CEST
More info: https://malikaihle.github.io/OSC-Open-Research-Summer-School-2023/
Free registration: https://www.pretix.osc.lmu.de/lmu-osc/lectures/
'From 2016 to 2017, the largest single-year drop in overall cancer mortality so far — 2.2% — was reported, spurred by rapid declines in lung cancer mortality that have been partially attributed to the approval of immune checkpoint inhibitors (ICIs) and other new targeted therapies'
Thiago Carvalho
boosted
#proteomics | EMBL-EBI Proteomics bioinformatics | 15-19 Jul, 2024 | Hinxton, UK --- https://www.ebi.ac.uk/training/events/proteomics-bioinformatics-1/
'Los archivos desclasificados muestran la visión de Washington sobre los acontecimientos que sucedían en Santiago de Chile en las horas previas al quiebre democrático que dio paso a la dictadura de Augusto Pinochet (1973-1990).'
'Using several high-throughput sequencing approaches, we show that the H/ACA complex is recruited to actively transcribed genes genome-wide, where it performs mRNA pseudouridylation. Moreover, we demonstrate that this modification reduces the rate of mRNA translation and that loss of dyskerin-mediated pseudouridylation results in global elevation of protein synthesis.'
#MolecularBiology #mRNA
Thiago Carvalho
boosted
This is Switzerland taking Russia's side. This is Switzerland effectively arming aggressor Russia by stopping defender Ukraine from arming itself.
The Swiss government will not allow almost 100 Leopard I tanks stored in Italy to be sold to Ukraine.
Thiago Carvalho
boosted
George Takei on the Ugly Danger of Scapegoating: “There are few things more terrifying than demagogic populism, sharpened dangerously into authoritarian rule, with minorities left at the mercy of those now in charge of writing and enforcing the laws.”
https://www.thedailybeast.com/george-takei-on-the-ugly-danger-of-scapegoating?ref=home
'Why would blood group make any difference to SARS-CoV-2? Several new studies offer possible explanations. One from Stowell and colleagues, recently published in Blood, suggests that having type A blood makes SARS-CoV-2 “stickier” to host cells.'
'Resistant pathogens killed 1.26mn people in 2019, according to an analysis published in the medical journal The Lancet. “All of modern medicine is upheld by our ability to control infectious disease. If we can’t control infection, we can’t administer chemotherapy, do invasive surgery, and preterm birth becomes really, really challenging and risky”
https://www.ft.com/content/e9aeb9a3-a93c-439b-ab81-a7c71266d992
Thiago Carvalho
boosted
More cancer screenings sounds like good news. But can the NHS cope with them?
'But scientists who study viral transmission see another lesson in the pandemic school closures: Had the indoor air been cleaner and safer, they may have been avoidable. The coronavirus is an airborne threat, and the incidence of Covid was about 40 percent lower in schools that improved air quality, one study found.'
#Covid #Covid19 #PublicHealth
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
