Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'While Aβ is clearly the initiating factor in the context of mutations in the genes encoding APP and, likely, presenilin 1 and presenilin 2, I propose that accumulation of pathogenic forms of tau is not a consequence of Aβ in all cases of sporadic AD'
#alzheimers #alzheimersdisease

https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(23)00166-2

It's 1:30 AM, I'm trying to reformat an NIH biosketch for NSF using the government's own sciencv website, hitting uninformative error messages every time I click a checkbox to add or remove a paper, and wondering if maybe there isn't a greater role for ChatGPT than I've ever acknowledged.

Postdoc position in locus coeruleus connectomics of resilience at MGH

Massachusetts General Hospital / Harvard Medical School

Exciting postdoc on #locuscoeruleus functional networks project in #Alzheimers in #Boston? Come join our fun, collaborative lab at MGH!

See the full job description on jobRxiv: https://jobrxiv.org/j...
https://jobrxiv.org/job/massachusetts-general-hospital-harvard-medical-school-27778-postdoc-position-in-locus-coeruleus-connectomics-of-resilience-at-mgh/?feed_id=57015

Biomedical Scientist / Molecular Biologist for Skin Cancer Research in
Deutschen Krebsforschungszentrum

See the full job description on jobRxiv: https://jobrxiv.org/job/biomedical-scientist-molecular-biologist-for-skin-cancer-research-in/?feed_id=57022

#ScienceJobs #hiring #research
Heidelberg #Germany #Researcher #Scientist
https://jobrxiv.org/job/biomedical-scientist-molecular-biologist-for-skin-cancer-research-in/?feed_id=57022

This is correct.

Cleaner air = cleaner lungs.

The row should be about the level of subsidy the government is providing (currently none) to support drivers of polluting vehicles. These shouldn't be penalised, but rather subsidised to upgrade their vehicles at no personal expense.
#ULEZ

https://www.theguardian.com/commentisfree/2023/aug/28/the-guardian-view-on-londons-low-emission-zone-doing-the-right-thing?CMP=Share_AndroidApp_Other

Strigolactones promote plant freezing tolerance by releasing the WRKY41-mediated inhibition of CBF/DREB1 expression
Shuhua Yang and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2022112999

Mercator Projection

Excuse me?
Google now moderates your saved bookmarks? The hell?

'From 2016 to 2017, the largest single-year drop in overall cancer mortality so far — 2.2% — was reported, spurred by rapid declines in lung cancer mortality that have been partially attributed to the approval of immune checkpoint inhibitors (ICIs) and other new targeted therapies'

https://www.nature.com/articles/s41573-023-00723-4

'To fill this gap, we present here bioinformatics analysis of 1702 proteins, selected from different aging-related databases, studies, and networks to evaluate the prevalence of intrinsic disorder in these proteins associated with aging.'

https://link.springer.com/article/10.1007/s00018-023-04897-3

'E quando as vemos lá vai o pessoal ver os corpos lindos delas a dançar. Isso é o exótico. Mas o batuque é resistência, vem de uma história de resistência de escravidão. Essa relação nunca é feita. Aquilo não é tipo resiliência nem boa vibe; aquilo é uma história. Uma história de resistência e está aqui na cidade de Lisboa e é importante percebê-la.'

https://www.publico.pt/2023/08/27/sociedade/entrevista/antonio-rapaz-lisboa-maior-urgencia-cidade-direito-lugar-2061265

@Interesting
Human gene identified that prevents most bird flu viruses moving to people
https://www.theguardian.com/science/2023/jun/28/human-gene-identified-prevents-most-bird-flu-viruses-moving-to-people?CMP=Share_AndroidApp_Other

“Every kid starts out as a natural-born scientist, and then we beat it out of them. A few trickle through the system with their wonder and enthusiasm for science intact.”

— Carl Sagan

#quote #CarlSagan

Faculty job alert! CSHL is hiring a faculty position in computational neuroscience, broadly defined. Deadline to apply is Sept 1, 2023 (the earlier the better).

https://cshl.edu/about-us/careers/faculty-positions/

Yes, I snapped this view today, a 1 min walk from your new office!