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Human rights activist and Scientist Rebellion co-founder Mike Lynch-White was imprisoned ten months ago for peacefully disrupting a factory providing weapons to Israel. In his own words, "the world has watched a genocide in slow motion."

Mike was arrested at the UK border in February and was sentenced to 23 months in prison in May for criminal damage after climbing onto the roof of Runcorn-based factory APPH. He received a longer sentence due to previous climate-related actions.

We’re looking for Workshops and Special Events for the 3rd Joint Congress on Evolutionary Biology in Montréal! Workshops and special events are a great way to build community around a theme, concept, or approach, so consider hosting if you have an idea! More information here:

evolutionmeetings.org/workshop

"When Claudia Goldin received her Nobel Memorial Prize in Economics, she was only the third woman to receive the award after Esther Duflo (2019) and Elinor Ostrom (2009). It was the first time in the history of the 54-year-old prize that women held more Nobels in economics than the uncles of Larry Summers (Paul Samuelson and Kenneth Arrow). An anecdote, but it illustrates the level of representation of women in economics."

blogs.lse.ac.uk/impactofsocial

Listen to Univision anchor Jorge Ramos. He charged that his network gave too friendly an interview with Trump, and in so doing it “put in doubt the independence of our news department.” Ramos added that Univision cannot “offer Trump an open microphone to broadcast his falsehoods and conspiracy theories." Let it be a warning to all news media.

“Orchids have interested me as much as almost anything in my life,” Darwin wrote. In their forms, he saw a vast landscape of the forces of selective evolution, a dance they played with their environment and their pollinators. “My little darlings,” as he sometimes referred to orchids, became his model for further exploring the forces he so broadly described in The Origin of Species. Just three years after the publication of that shattering work, he had produced his tome puzzling over the multitudinous, striking habits of orchids: On the Various Contrivances by Which British and Foreign Orchids Are Fertilised by Insects, and On the Good Effects of Intercrossing.'

nautil.us/why-is-everything-an

'Instead, the social media giant “routinely continued to collect” children’s personal information, like their locations and email addresses, without parental permission, in violation of a federal children’s privacy law, according to the court filing.'

nytimes.com/2023/11/25/technol

'What went wrong? It isn’t that the past 25 years of consciousness studies haven’t been productive. The field has been incredibly rich, with discoveries and applications that seem one step from science fiction. The problem is that, even with all these discoveries, we still haven’t identified any neural correlates of consciousness. That’s why Koch lost the bet.'

aeon.co/essays/are-we-ready-to

It's difficult to explain how great the original Netflix DVD service was - how much better than instantly streaming Vin Diesel it was to be able to get in a day or two anything from the Criterion Collection, for example.

thesmartset.com/the-long-goodb

#^Battling implicit bias


Training is a cheap solution to a hard problem. It is the systems that allow for biased behaviour that need to change
- by Jeffrey To

Read at Aeon

While I wait for my copy of my friend Dann McDorman's debut novel "West Heart Kill" to arrive, I enjoyed this podcast interview.

youtube.com/watch?v=atHr6suW8_

Tunnelling #nanotube formation is driven by #Eps8/#IRSp53-dependent linear #actin polymerization
Michael Henderson, Chiara Zurzolo, Patricia Bassereau and coworkers
embopress.org/doi/full/10.1525

"Life is for each man a solitary cell whose walls are mirrors."
Lazarus Laughed

Eugene O’Neill American dramatist and winner of the Nobel Prize for Literature in 1936 died #OTD in 1953. His poetically titled plays were among the first to introduce into the U.S. the drama techniques of realism. The tragedy Long Day's Journey into Night is often included on lists of the finest U.S. plays in the 20th century. via @wikipedia

Books by Eugene O'Neill at PG:
gutenberg.org/ebooks/author/13

#books #theatre

'Além disso, a pretensa meritocracia do numerus clausus é uma tautologia: o sistema académico define o que é considerado “melhor” e depois declara que os aceites são os “melhores”. Mas onde está a demonstração que médias altas identificam os mais aptos para determinada profissão? Alguém acha que os melhores médicos se escolhem pela capacidade de receber e memorizar “aprendizagens” de Português ou Biologia no ensino secundário?'
@lmrocha

publico.pt/2023/11/27/opiniao/

Androgen deprivation + anti-PD1 trial for .

"These data provide a reasonable therapeutic rationale to combine ADT with immunotherapy, thus leveraging anti-tumor immunity while mitigating the ADT-mediated induction of suppressive mechanisms. To that end, we designed and initiated the PRIME-CUT Phase II trial (NCT03951831) treating men with metastatic castration-sensitive prostate cancer (mCSPC) with a combination of standard of care chemo-hormonal therapy and anti-PD-1 immunotherapy using the anti-PD-1 immunotherapy cemiplimab."

cell.com/cancer-cell/fulltext/

"Here, using single-cell RNA sequencing, we demonstrate that a B cell transcriptional program poised for effector functions represents the major immune perturbation in blood samples from children with active INS. This transcriptional profile was associated with an extrafollicular B cell response marked by the expansion of atypical B cells, marginal zone-like B cells, and antibody-secreting cells"

nature.com/articles/s41467-023

"Our study provides temporal transcriptional patterns and uncovers pan-tissue parallels between prostate and lung cancers, as well as connections to normal neuroendocrine cell states."

cell.com/cancer-cell/fulltext/

"We genetically rendered a single MALT1 substrate, the RNA-binding protein (RBP) Roquin-1, insensitive to MALT1 cleavage. These Rc3h1Mins/Mins mice showed normal immune homeostasis."

pnas.org/doi/10.1073/pnas.2309

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