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John Greenleaf Whittier American poet and advocate of the abolition of slavery in the United States was born #OTD in 1807. At age 19 he submitted his poem “The Exile’s Departure” to the abolitionist William Lloyd Garrison for publication in the Newburyport Free Press, and it was accepted. Garrison encouraged other poetic contributions from Whittier, and the two men became friends and associates in the abolitionist cause.

John Greenleaf Whittier at PG:
gutenberg.org/ebooks/author/45

#books #literature

I think that we generally do not make enough use of clinical data. We could learn so much, if all clinical data were systematically collected and analysed...

jamanetwork.com/journals/jama/

Just Giorgia Meloni having a laugh with a fellow fascist. Probably joking about asylum seekers, stealing tents from the homeless, food banks or something equally hilarious.

#giorgiameloni #RishiSunak #RishiSnake #Tories #fascists

'The people who had longed for a “normal” Western economy faced callous, bewildering transitions. They became the subjects of imported neoliberal experiments, often driven by wild-eyed Hayekian or Friedmanite fanatics like the ones I met in Warsaw as communism foundered in 1989'

nybooks.com/articles/2023/12/2

"However, with growing emphasis placed on representative inclusion in research by the public and research funders, a practical, evidence-based approach to capture inclusive and representative research samples, minimize bias and promote equity is required"

nature.com/articles/s41591-023

William Thomson, Baron Kelvin Irish engineer, mathematician, and physicist died #OTD in 1907.

Absolute temperatures are stated in units of kelvin in his honour. While the existence of a coldest possible temperature, known as absolute zero, was known prior to his work, Kelvin is known for determining its correct value as approximately −273.15 degrees Celsius. Kelvin's work in thermodynamics led to the idea that energy can not pass spontaneously from a colder object to a hotter object.

#physics

"In contrast to the COVID vaccines, these mRNA cancer vaccines show remarkable differences in vaccine design and delivery approach, such as for the lipid carrier, the modifications or absence of modifications to the mRNA molecule, and route of immunization."

sciencedirect.com/science/arti

Today:

"Feira do Prato Falante" Porto at @this_is_the_spot from 14h to 19h (rua São Victor 143 A).

'Federal research agencies provide the primary source of support for the majority—56%—of U.S.-based biological and biomedical postdocs, whereas only 17% are primarily funded by institutions. “What I personally hope is there's a call for institutions to offer more support to postdocs,” says working group member Chrystal Starbird, who started her post as an assistant professor of biochemistry and biophysics at the University of North Carolina at Chapel Hill in February after encountering many challenges during her postdoc years. “I think institutions have forgotten that they can also have some buy in and some commitment to postdocs as well.”

science.org/content/article/ni

"Netanyahu was building alliances with the illiberal governments of Central European countries, such as Poland and Hungary, in part to prevent an anti-occupation consensus from solidifying in the European Union. For this, he was willing to lie about the Holocaust."

newyorker.com/news/the-weekend

Minimal Residual Disease (MRD) Status Predicts Outcome in Patients With Previously Untreated Follicular #Lymphoma

Just saying: Validating MRD as a biomarker predicting living longer or better (clinical benefit) is needed

... as the standard time to event endpoints (PFS, survival) take many many years to assess for indolent (slow growing) #cancer.

pubmed.ncbi.nlm.nih.gov/380964

#MEDMASTODON #lymphoma #Cancer #fedscience
#ClinicalResearch #Oncology #Medicine #lymsm @majorajay

"As the Internet Archive appeals a court decision blocking alternatives to surveillance-ridden digital book licenses, a new report reveals that the world’s largest publisher may be selling readers’ intimate personal data to the highest bidder."

fastcompany.com/90996547/e-boo

Really important study that I hope those in charge of decisions re Covid19 vaccine campaigns pay heed to: data from >10.5 million people shows that case Fatality rate for Covid highest in unvax esp older and lowest in fully vax but significantly increases to after 6 months post booster! This strongly supports that until long term vaccines available/purchased that booster campaign needed journals.sagepub.com/doi/10.11

"Here, we leveraged recent advances in ribosome profiling and MS to investigate the factors limiting detection of noncanonical proteins in yeast. We show that the low detection rate of noncanonical ORF products can largely be explained by small size and low translation levels and does not indicate that they are unstable or biologically insignificant."

journals.plos.org/plosbiology/

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