"I fairly often encounter people who believe that Europe suffers from mass unemployment and has lagged far behind the United States technologically. But this view is decades out of date. At this point adults in their prime working years are actually somewhat more likely to be employed in major European nations than in America. Europeans also know all about information technology, and productivity — gross domestic product per hour worked — is virtually the same in Europe as it is here."
https://www.nytimes.com/2024/01/30/opinion/europe-economy-problems-policy.html
Good summary of some of the issues regarding Covid and risks looking ahead https://news.sky.com/story/the-virus-is-still-evolving-at-an-incredible-rate-how-widespread-is-covid-now-and-how-many-people-are-dying-with-it-13059424
The Cerro de Caballo (3009m) in Spain's Sierra Nevada comes out of the cloud above the hills between Albuñuelas and Lentegí.
As digital media took off in the 2010s, few believed magazines could survive. While the industry isn’t what is once was, magazines are still very much alive, but why?
https://theconversation.com/magazines-were-supposed-to-die-in-the-digital-age-why-havent-they-217371?utm_term=Autofeed&utm_medium=Social&utm_source=Facebook#Echobox=1706688912
'The technology may transform agriculture in LMICs beyond the genomic level: local farmers seem happy, Runo told the journal Nature, to source seeds from regional researchers rather than multinationals. The global spread of gene-editing technology may end up dispersing the commercial power currently concentrated in corporate labs — and raises the prospect of African-grown gene-edited crops being sold beyond the continent.'
https://www.ft.com/content/10a7cd0c-78f0-409a-9808-a71a11e7b46a
Lausanne Omics Days 2024, 22-23 February:
Deep learning in Biology and Medicine
Variation in genome structure and organization
Metabolomics – Towards understanding biological interaction
Single cell and spatial transcriptomics
https://wp.unil.ch/gtf/lod-2024/
#genomics #DeepLearning #ComputationalBiology #bioinformatics #Metabolomics #SingleCell
'Vertex Pharmaceuticals of Boston announced Tuesday that it had developed an experimental drug that relieves moderate to severe pain, blocking pain signals before they can get to the brain. It works only on peripheral nerves — those outside the brain and the spinal cord — making it unlike opioids. Vertex says its new drug is expected to avoid opioids’ potential to lead to addiction.'
https://www.nytimes.com/2024/01/30/health/vertex-pain-medicine-non-opioid.html
'Embora bom e barato seja um objetivo apelativo, não é realista querermos investigação científica de qualidade e, ao mesmo tempo, não investirmos de forma consequente nesse desígnio. Seguramente que os recursos destinados ao SNCT têm necessariamente de ser adequados à realidade do país, mas se este investimento for demasiado curto, imprevisível e mal estruturado dificilmente pode originar os retornos que queremos.'
https://www.publico.pt/2024/01/31/ciencia/opiniao/omeletes-ovos-ciencia-portugal-2077903
Douglas Allchin, Jonathan Osborne, and I have a new paper out about teaching science in this age of online misinformation.
The idea is simple: we tell people to trust the science, but we rarely teach students about the social processes that make it trustworthy.
Climate models have correctly predicted #globalwarming for decades.
NASA‘s Gavin Schmidt explains a few of the tricks that contrarians use to make you believe otherwise.
Spencer’s Shenanigans https://www.realclimate.org/index.php/archives/2024/01/spencers-shenanigans/
"The idea that misfolded beta-amyloid might be a prion-like disease has also been around for a long time, because it makes a lot of sense. Indeed, histopathology of patients who died from transmitted CJD has already shown (in several studies) the presence of aggregated beta-amyloid protein, with the implication that this could have been transmitted as well. There have been also reports for over ten years that injection of human Alzheimer's brain proteins into mice leads to AD-like pathology in mouse brains. In 2018, the same authors of this new paper showed that archived samples of toxic cadaveric growth hormone did indeed contain substantial amounts of soluble beta-amyloid, and that injected thse into mice caused such pathology as well. Putting these and other lines of evidence together, this newest paper fits a puzzle piece right where you'd expect one to go. It shows that some of the growth-hormone-treated patients did indeed go on to develop #Alzheimer's, as feared."
https://www.science.org/content/blog-post/infectious-amyloid-infectious-alzheimer-s
If you're in Berlin:
"The show, “Josephine Baker: Icon in Motion,” which runs through April 28, is a small but dense and deeply imaginative reconsidering of her life and work. The museum’s director, Klaus Biesenbach (formerly of MoMA and the Los Angeles County Museum of Art) has curated the show with the artist Kandis Williams, the scholar Terri Francis and the curator Mona Horncastle: The result emphasizes the importance of multiple interpretations."
https://www.nytimes.com/2024/01/30/arts/design/josephine-baker-exhibition-berlin.html
The Little Book of Irish Research
A few months ago, I blogged on the occasion of the launch by Simon Harris TD, Minister for Further and Higher Education, Research, Innovation and Science, of the Little Book of Irish Research. This book, which is aimed at school students, so is written at an elementary level, gives quick summaries of areas of research that the general public said that they were interested in, grouped into sixteen themes, and it will be distributed to…
http://telescoper.blog/2024/01/30/the-little-book-of-irish-research-2/
Yes! "CC0 is the best choice to maximize data reuse."
"The expectation that one be cited for one’s scholarly outputs, such as a hypothesis published in an article, is a standard research community practice. It is not, however, a legal requirement." #CC0 #OpenScience
From: @datadryad
https://mstdn.science/@datadryad/111846803440956895
'The Duchess was a vanishingly rare creature: a self-taught natural philosopher writing in the decades when natural philosophy was developing into what we now call science, a professionalized field that would embrace the new disciplines of astronomy, geography, mathematics, and physics. She also belonged to an emergent species: the female intellectual.'
'There are lots of lurid tales about the Wa, who once made a practice of beheading intruders. But the book’s bigger story involves America’s hapless war on drugs. Winn spent several years interviewing Wa citizens, U.S. Drug Enforcement Agency lifers and CIA spies. He learned that Wa-produced heroin found its way to American soldiers in Vietnam, and in the years that followed, CIA-linked opportunists helped the Wa become a force in Southeast Asia’s meth trade.'
'The Shanahan Foundation Fellowship at the Interface of Data and Neuroscience was created to provide freedom and flexibility to promising young scientists from diverse fields, as they work alongside neuroscientists at the Allen Institute and University of Washington. The three-year fellowship provides Ph.D.s from data science, computer science, physics, mathematics, and many other fields the mentorship and support to pursue their own research interests with our data.'
https://alleninstitute.org/careers/internships-and-postbac/shanahan-foundation-fellowship/
Another newsletter has joined the Substack Migration:
Richard MacManus, @ricmac, Cyberculture, https://cybercultural.com/, A newsletter about tech history and its impact on our culture.
"I wanted a solution that was based on the open web and that was entirely under my control... from centralized platform to open web, from corporate to indie, from being controlled to taking back control."
Substack Migrantion Roll Call >>> https://mastodon.online/@mastodonmigration/111766603495656560
'The present study illustrates great potentials of chimeric antigen receptor (CAR-T) cells targeting B cell maturation antigen in treating anti-signal recognition particle myopathy, with sustained depletion of autoantibodies and therapeutic efficacies beyond 18 mo.'
#immunotherapy #CARTcells
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com