Interesting paper on how the USP7 protein contributes to the activity of non-canonical PRC1.1 and 1.6 complexes. USP7 positively contributed to H2AK119ub, but re-expression of USP7 in knockout cells does not change H3K27me3 levels

#ChromatinToot

https://www.science.org/doi/10.1126/sciadv.abq7598