jonmoulton @jonmoulton@social.cleverlibre.org

Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. https://www.pnas.org/doi/abs/10.1073/pnas.2215071120 #Morpholino

Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction. https://journals.biologists.com/dev/article/150/1/dev201058/286546/Hydrozoan-sperm-specific-SPKK-motif-containing #Morpholino

C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity. https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB01759H #Morpholino

Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs. https://www.nature.com/articles/s41598-022-26614-z #Morpholino

maea affects head formation through ß-catenin degradation during early Xenopus laevis development. https://onlinelibrary.wiley.com/doi/10.1111/dgd.12828 #Morpholino

Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA. https://www.embopress.org/doi/abs/10.15252/embr.202154350 #Morpholino

SCGN deficiency is a risk factor for autism spectrum disorder. https://www.nature.com/articles/s41392-022-01225-2 #Morpholino

Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00939-8 #Morpholino

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010586
#Morpholino

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish. https://www.mdpi.com/2073-4409/12/1/144 #Morpholino

The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation. https://www.mdpi.com/2073-4409/12/1/4 Vivo-#Morpholino

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier.
https://www.sciencedirect.com/science/article/abs/pii/S0012160622002366 Vivo-#Morpholino

Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes. https://onlinelibrary.wiley.com/doi/10.1111/cpr.13391 #Morpholino

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development. https://www.life-science-alliance.org/content/6/3/e202201800 #Morpholino

Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events. https://www.sciencedirect.com/science/article/pii/S2211124722017661 #Morpholino

Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish. https://www.mdpi.com/2073-4425/14/1/35 #Morpholino

Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish.
https://link.springer.com/article/10.1007/s00018-022-04669-5 #Morpholino

Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00943-y #Morpholino

Evaluation of Cardiovascular Toxicity of Folic Acid and 6S-5-Methyltetrahydrofolate-Calcium in Early Embryonic Development. https://www.mdpi.com/2073-4409/11/24/3946 #Morpholino

Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00587 #Morpholino