jonmoulton @jonmoulton@social.cleverlibre.org

Long-range chemical signalling in vivo is regulated by mechanical signals. https://www.biorxiv.org/content/10.1101/2024.02.15.580459v1 #Morpholino

FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System. https://www.ahajournals.org/doi/suppl/10.1161/CIRCULATIONAHA.123.064489 #Morpholino

Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: Therapeutic implications. https://www.sciencedirect.com/science/article/pii/S2666247724000137 #Morpholino

Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia. https://www.biorxiv.org/content/10.1101/2024.02.14.580281v1 #Morpholino

Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae093/7608825 #Morpholino

Apela promotes blood vessel regeneration and remodeling in zebrafish. https://www.nature.com/articles/s41598-023-50677-1 #Morpholino

(AJMC Article): Positive Phase 2 Data for SRP-5051 in Duchenne Muscular Dystrophy https://www.ajmc.com/view/positive-phase-2-data-for-srp-5051-in-duchenne-muscular-dystrophy #Morpholino

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0297420 #Morpholino

Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos. https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP285490
#Morpholino

An alternative strategy to increasing influenza virus replication for vaccine production in chicken embryo fibroblast (DF-1) cells by inhibiting interferon alpha and beta using peptide-conjugated phosphorodiamidate #Morpholino oligomers https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.001807

(Fish Diseases conference program) Learning more from knockdowns and knockouts https://fish-models.com/gene-tools/ #Morpholino

Comprehensive analysis of diel rhythmic expression of the medaka toll-like receptor gene family. https://www.sciencedirect.com/science/article/abs/pii/S0145305X24000156 #Morpholino

Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance. https://www.mdpi.com/1422-0067/25/4/2079 Vivo-#Morpholino

Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development. https://www.nature.com/articles/s41375-024-02165-2 #Morpholino

Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator. https://elifesciences.org/articles/80803 #Morpholino

Synthesis of Self Permeable Antisense PMO Using C5-Guanidino-Functionalized Pyrimidines at the 5'-End Enables Sox2 Downregulation in Triple Negative Breast Cancer Cells. https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.3c00924 #Morpholino

Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes. https://www.nature.com/articles/s10038-024-01222-z #Morpholino

Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development -A Subtype of Craniovertebral Junction Malformation. https://www.e-neurospine.org/journal/view.php?doi=10.14245/ns.2347238.619 #Morpholino

TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning. https://www.tandfonline.com/doi/full/10.1080/27694127.2024.2306766 #Morpholino

Endocardium gives rise to blood cells in zebrafish embryos. https://www.sciencedirect.com/science/article/pii/S2211124724000640 #Morpholino