jonmoulton @jonmoulton@social.cleverlibre.org

Innate immune sensing of pathogens and its post-transcriptional regulations by RNA-binding proteins. Review.
https://link.springer.com/article/10.1007/s12272-023-01429-2
#Morpholino

Tmem88 confines ectodermal Wnt2bb signaling in pharyngeal arch artery progenitors for balancing cell cycle progression and cell fate decision. https://www.nature.com/articles/s44161-023-00215-z #Morpholino

DG9-conjugated morpholino rescues phenotype in SMA mice by reaching the CNS via a subcutaneous administration . https://insight.jci.org/articles/view/160516 #Morpholino

(Article): Unlocking New Possibilities in Research, Therapeutics, and Beyond with #Morpholino Antisense Oligos. https://www.pharmasalmanac.com/articles/unlocking-new-possibilities-in-research-therapeutics-and-beyond-with-morpholino-antisense-oligos

RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00058-X #Morpholino

The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs. https://www.nature.com/articles/s41467-023-36114-x #Morpholino

The involvement and therapeutic potential of lncRNA Kcnq1ot1/miR-34a-5p/Sirt1 pathway in arsenic trioxide-induced cardiotoxicity. https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-023-03895-0 #Morpholino

Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries. https://www.jhep-reports.eu/article/S2589-5559(22)00224-5/fulltext #Morpholino

My wife's lab's website: not a #Morpholino paper, but certainly Morpholino related! She makes delivery-enabled Morpholino conjugates (e.g. PPMOs). https://athos213.github.io/MoultonResearchGroup/

Crb3 stabilizes activated Ezrin-Radixin-Moesin to organize the apical domain of multiciliated cells. https://www.biorxiv.org/content/10.1101/2023.01.24.525309v1 #Morpholino

Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. https://www.sciencedirect.com/science/article/pii/S1534580722008954 #Morpholino

Wnt4 and ephrinB2 instruct apical constriction via Dishevelled and non-canonical signaling. https://www.nature.com/articles/s41467-023-35991-6 #Morpholino

Integrative genetic analysis illuminates ALS heritability and identifies risk genes. https://www.nature.com/articles/s41467-022-35724-1 #Morpholino

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. https://www.pnas.org/doi/10.1073/pnas.2208941120 #Morpholino

Morpholino-Mediated Exons 28-29 Skipping of Dysferlin and Characterization of Multiexon-skipped Dysferlin using RT-PCR, Immunoblotting, and Membrane Wounding Assay. https://link.springer.com/protocol/10.1007/978-1-0716-2772-3_11 #Morpholino

Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis. https://www.mdpi.com/2073-4409/12/3/376/htm #Morpholino

SMIM36, a novel and conserved microprotein, is involved in retinal lamination in zebrafish. https://www.biorxiv.org/content/10.1101/2023.01.14.524032v1 #Morpholino

Multiple pkd and piezo gene family members are required for atrioventricular valve formation. https://www.nature.com/articles/s41467-023-35843-3 #Morpholino

Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish. https://www.mdpi.com/1422-0067/24/2/1733 #Morpholino

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis. https://link.springer.com/article/10.1007/s10456-023-09865-w #Morpholino