Ciliary length regulation by intraflagellar transport in zebrafish. https://www.biorxiv.org/content/10.1101/2024.01.16.575975v1 #Morpholino
Dyrk1a is required for craniofacial development in Xenopus laevis. https://www.biorxiv.org/content/10.1101/2024.01.13.575394v1 #Morpholino
Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS). https://www.biorxiv.org/content/10.1101/2024.01.09.574075v1 #Morpholino
Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. https://www.sciencedirect.com/science/article/pii/S096098222301655X #Morpholino
amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. https://www.mdpi.com/1422-0067/25/2/734 #Morpholino
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation. https://www.nature.com/articles/s41467-023-44611-2 #Morpholino
Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. https://www.nature.com/articles/s42003-023-05692-3 #Morpholino
Macrophages inhibit extracellular hyphal growth of A. fumigatus through Rac2 GTPase signaling. https://journals.asm.org/doi/10.1128/iai.00380-23 #Morpholino
Piezo1-dependent regulation of pericyte proliferation by blood flow during brain vascular development. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01663-7 #Morpholino
(Brief article): Dyne Therapeutics: Positive Initial Clinical Data from DMD DELIVER Trial. https://defeatduchenne.ca/dyne-therapeutics-positive-initial-clinical-data-from-dmd-deliver-trial/ #Morpholino
The RhoGEF Trio is transported by microtubules and affects microtubule stability in migrating neural crest cells. https://www.sciencedirect.com/science/article/pii/S266729012300075X #Morpholino
Histone lactylation couples cellular metabolism with developmental gene regulatory networks. https://www.nature.com/articles/s41467-023-44121-1 #Morpholino
(Article): Clinical Potential of AOC 1044 in Treating Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping. https://www.neurologylive.com/view/clinical-potential-aoc-1044-treating-duchenne-muscular-dystrophy-amenable-exon-44-skipping #Morpholino
Development of FKBP5 ASOs to mitigate tau pathology. https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.082780 Vivo-#Morpholino
AMONDYS 45 (Casimersen), a Novel Antisense Phosphorodiamidate Morpholino Oligomer: Clinical Considerations for Treatment in Duchenne Muscular Dystrophy. https://www.cureus.com/articles/215610-amondys-45-casimersen-a-novel-antisense-phosphorodiamidate-morpholino-oligomer-clinical-considerations-for-treatment-in-duchenne-muscular-dystrophy#!/ #Morpholino
Loss of coactosin-like F-actin binding protein 1 (Cotl1) decreases platelet-mediated osteoclastogenesis and causes osteopetrosis phenotypes in mouse. https://www.medrxiv.org/content/10.1101/2023.12.20.23300337v1 #Morpholino
Cost-effective strategies to knock down genes of interest in the retinas of adult Zebrafish. https://www.frontiersin.org/articles/10.3389/fncel.2023.1321337/abstract Vivo-#Morpholino
TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning. https://www.biorxiv.org/content/10.1101/2023.03.29.534583v3 #Morpholino
Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina. https://www.nature.com/articles/s41467-023-44142-w #Morpholino
β-adrenergic receptor regulates embryonic epithelial extensibility through actomyosin inhibition. https://www.cell.com/iscience/fulltext/S2589-0042(23)02546-4 #Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.