@tillianisafox Speaking as an engineer, yes, it certainly is. An example being the Castle Bravo thermonuclear test -- unintentionally the largest the U.S. ever detonated.
It was supposed to deliver around 6 to 10 megatons but ran away to 15 megatons due to physics we didn't yet understand at the time. It worked considerably better than expected. Oops.
Nuke tests were never supposed to discover new physics but this one did.
@tillianisafox By the way, there's a lot of wrong information out there on YouTube etc. about what happened and what went wrong. If you want an explanation let me know.
In any case, the explosion yielded about twice the output expected so a lot of unexpected damage was done. Nobody was amused. This test scared the crap out of everybody including the Russians and resulted in a careful re-examination of the whole nuclear weapons program.