Well, I had a response, it's pretty much what I expected, but I'm not going to lie, everything will be easier if the paper is accepted. But essentially, according to the reviewer, I have a coherent black box. So if you wanna forecast anything related to COVID here is the paper. Just "forget the biology" stick to the numbers.
https://www.researchsquare.com/article/rs-2797280/v3
And the interactive summary.
https://www.kaggle.com/code/tavoglc/a-computational-description-of-sarscov2-adaptation