3D hydrogel #BloodBrainBarrier model (EC+SMC+Astrocyte, ɸ 600 µm)
+Defined, zonated flow profiles
Transcriptomics of #EndothelialCell with Disturbed vs Laminar flow for 24 h->
#Lumican in #VascularPermability
Dr. Peter Galie lab Fluids Barriers CNS 2022
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-022-00389-x
'We report on the protocolized use of tecovirimat (SIGA Technologies), an antiviral drug with activity against orthopoxviruses (including monkeypox and smallpox),1 under an expanded access program for all patients with monkeypox virus (MPXV) disease in Mbaïki, Central African Republic, between December 2021 and February 2022.2 Included in the study were 14 patients in whom MPXV infection had been diagnosed.'
https://www.nejm.org/doi/full/10.1056/NEJMc2210015?query=featured_home
1. It's Friday. Time for a #flu 🧵
So #influenza-like illness is still rocking the country. This year's epi curve - the one to the far left - is incredibly high & sharp. That's not all flu & it tells us nothing about severity. It does tell us a lot of people have respiratory infections these days.
@rastinza este tipo de comentarios me recuerda a una película de unos ratones rusos que viajan a america y se la pasan cantando "pero no hay gatos en América ya no más preocupacion". Y bajando del barco tremendo gatote los estaba esperando en el muelle.
Hermanos Españoles, si de verdad piensas estás cosas vos no tienes ni idea de los otros gobiernos del mundo.
En mi país, Italia, el primero ministro fue acusado por varias conductas criminales y el acusó los jueces de parcialidad, no se presentó a los procesos y hice leyes ad persona para no ir a juicio.
Un fil de discussion d’une science en train de se faire sur Twitter ! « they should have preprinted this » (via @LillyLyle)
---
RT @K_G_Andersen
🤔
"data revealed genetically diverse Omicron ancestors already existed across Africa by August 2021. Mutations, altering viral tropism, replication and immune escape, gradually accumulated in the spike gene.”
Definitely a must-read!
https://www.science.org/doi/10.1126/science.add8737
https://twitter.com/K_G_Andersen/status/1598422985077305346
@quesoloAna chilaquiles verdes con coquita de vidrio ![]()
Hi #ScienceMastodon, I'm a physician-scientist and immunologist. Our lab studies how aberrant immunity at barrier surfaces drive disease. I have a special interest in type 2 immunity and allergic diseases, but am generally fascinated by #immunology and #biology.
I will never understand far right Conservatives who claim to be fans of #StarTrek but who then complain about current Trek being “too woke”
From Day 1 the entire premise of the Federation is that it’s a post-scarcity socialist utopia whose mission is scientific discovery and the peaceful exploration of space and discovery of new cultures.
The shows have always pushed the social boundaries of the times they aired in. Trek isn’t “turning woke”, Star Trek has always been woke. How’d you not know?
In two weeks you helped us build here a community of over 42,000 people. Thank you for remembering with us.
Super happy to share the first preprint from my PhD:
“Identifying Content-Invariant Neural Signatures of Phenomenal Magnitude” with
Lau Andersen, @smfleming and @nadine_dijkstra!
If you like work on consciousness and/or higher-order theories this might be for you!
The Holocaust did not begin with killing; it began with words.
Genocides do not start with mass murder. That's where they end up.
Genocides & other mass atrocity crimes begin with words - specifically, with powerful people dehumanizing a minority.
Once they are seen as less than human, anything is possible, even mass murder.
👉 You can speak out loudly today for the rights of others, or you can stay silent & wait for tomorrow, when your rights will be taken away too.
Changes in gut microbiome composition drive fentanyl intake and striatal proteomic changes https://www.biorxiv.org/content/10.1101/2022.11.30.518531v1?med=mas
I like to know stuff