Tavo @tavoglc@social.cleverlibre.org

Este libro es maravilloso, recomendado para aquellos que quieran saber un poco más sobre sus cuerpos y los medicamentos que tomamos. Se hace entender muy bien

Masks Are a Proven Way to Defend Yourself from Respiratory Infections.

Respiratory viruses have rebounded hard after COVID seclusion, and masks are one of the best ways to avoid getting them

https://www.scientificamerican.com/article/masks-are-a-proven-way-to-defend-yourself-from-respiratory-infections/

Definitely didn’t need to wake up to this article. “The flush of a commercial toilet releases a Vesuvius-like cloud of tiny droplets and aerosol particles that reaches more than 5 feet above the seat.” #MedMastodon #medicine #covid #gross https://www.nature.com/articles/s41598-022-24686-5 https://www.latimes.com/science/story/2022-12-23/green-lasers-reveal-you-should-close-the-toilet-lid-before-you-flush

Stephen Colbert:

“In the U.S. alone, the COVID-19 vaccines have saved more than 3 million lives and helped prevent 18.5 million hospitalizations. And if that’s not enough, because idiots in your party politicize the vaccine, almost twice as many Republicans died from COVID before the midterms than Democrats. Y’all killed your own voters. It’s the stupidest political strategy since the Whig slogan of 1840, ‘Tippecanoe and Taunt a Grizzly.'”

#COVID #Republicans

https://www.dailykos.com/stories/2022/12/15/2142004/-Colbert-eviscerates-stupid-motherPfizer-DeSantis-over-investigation-into-COVID-19-vaccines

A look at some of the most beautiful and unusual examples from the first 100 years of the "modern" book cover, since the rise of publishers' bindings circa 1820: https://buff.ly/36aQW24

#books #bookcover #bookcovers #bookart #coverart #art #illustration #bookillustration #booklovers #bibliophile #bookshelves #art #bookshelf #bookporn #bookaddict #histodon

I see a lot of newer people looking for jobs or hires around the fediverse, and I just wanted to let y'all know we have a hashtag for that: #getfedihired

You will have more success if you're using it :)

​

Postdoc position open on computational neuroscience. Come and join me and Sadra Sadeh on a collaborative project. The aim is to develop biologically-inspired computational models of neuronal networks, in order to study the neuronal mechanisms underlying multisensory processing. More info: https://crick.wd3.myworkdayjobs.com/External/job/London/Postdoctoral-Project-Research-Scientist---Iacaruso-Lab_R1044-1

Twitter changed science — what happens now it’s in turmoil?
The microblogging platform has transformed research communication, but its future is in doubt.

https://www.nature.com/articles/d41586-022-04506-6

ME HA TOCADO

Me ha tocado la suerte de seguir cumpliendo mi sueño de poder publicar mis libros y que esta vez sea con un prólogo de Jon Sistiaga y una encuadernación preciosa.

POR FIN TENGO MI LIBRO.

Ojo que han aparecido en un polígono con las cajas de OTRO REPARTO.

Obviamente ya hay reclamación puesta, que se ha tenido que ir mi editora a por ellos y acaba de traermelos.

A study shows that an encapsulation method for vitamin A improves the nutrient’s stability during cooking and long-term storage while allowing it to be absorbed into the body, potentially helping to develop strategies against vitamin A deficiency. In PNAS: https://www.pnas.org/doi/10.1073/pnas.2211534119

My favourite time of year... the #BMJ christmas edition! This year the article that resonates is "Global Health Nonsense" Hope I am not offending but it rings true, we need to be careful that we do not use words and jargon that make it harder to understand what it is we are trying to do or focus too much on the new and innovation that the basics are forgotten. As the old adage goes... KISS (Keep it simple stupid!). Good pull out bingo card included!
https://www.bmj.com/content/379/bmj.o2932

"Here, we tested the ability of the #leishmania major sphingolipids inositol phosphorylceramide (IPC), and ceramide to shelter ergosterol by preventing binding and cytotoxicity of the sterol-specific toxins streptolysin O and perfringolysin O using flow cytometry. In contrast to mammalian systems, Leishmania sphingolipids did not preclude toxin binding to sterols in the membrane. However, IPC interfered with cytotoxicity."

#Preprint

https://www.biorxiv.org/content/10.1101/2022.06.15.496300v3#review

"The privileged treatment is part of a broader pattern, a Times investigation found. For years, NYU’s emergency room in Manhattan has secretly given priority to donors, trustees, politicians, celebrities, and their friends and family, according to 45 medical workers, internal hospital records and other confidential documents reviewed by The Times."

https://www.nytimes.com/2022/12/22/health/nyu-langone-emergency-room-vip.html

Aquí podemos ver animaciones que explican cómo se transmite el coronavirus SARS-CoV-2.
Vía Riken. #COVID19

This is one of those stories that either is the start of something huge or will sink like a stone: not much in between.

#Tessera's claims are ambitious but not unprecedented. One of our clients does something similar with stem cells, and they have a product that's actually made it to market. As far as I can tell, Tessera is claiming the ability to do this in all kinds of cells, with whole living organisms. Which would be a really big deal.

From a bioinformatics / biostatistics perspective (you knew that was coming) I have Questions about consistency. Doing it once, or ten times, or a thousand, isn't enough. You need to do it *trillions*, very accurately indeed. With cell cultures you just screen out the cells that didn't do what you wanted and keep the ones that did: insert "bury their mistakes" joke here. And with stem cells it's particularly easy to know when you have it right.

"65 percent efficiency—20 times the rate at which it performed unintended or errant edits" sounds quite good on a cell-by-cell basis, although I'd like to see the error bars on those numbers. In a patient, it would be an unmitigated disaster. Congratulations, we've cured your muscular dystrophy ... and given you ten different types of cancer.

More generally, their secrecy does not fill me with confidence, of the 95% variety or any other. As I've said many times before, science done in secret isn't science at all, it's alchemy.

Well. It's early days yet. Let's just hope Tessera isn't another Theranos, because I am *really tired* of that. If they do achieve any of what they're claiming, I'll be cheering them on.

#genetics #geneediting #genewriting #stemcell #bioinformatics #musculardystrophy #cancer

https://www.the-scientist.com/bio-business/can-gene-writing-deliver-what-gene-editing-can-t-70740

I'm desperately trying to permanently leave the bird app, but as a freelance journalist, it has also been a crucial tool in getting work

I'm posting my favorite stories from 2022 here with the hopes that I can find community here: (boosts very welcome)

1) My beat in Colombia can get pretty grisly. But this year also brought with a chance for me to focus on peace-building.

This was a fun one: I talked to demobilized guerillas who seek peace through brewing.

https://www.ozy.com/pg/newsletter/the-daily-dose/450065/

I know most of you don't want to think about #COVID, but I worry that too many people are unaware of the actual #risk and current situation, so I wrote this:
https://drkristenstuppy.substack.com/p/we-dont-talk-about-covid?sd=pf

@tootiatricians
#LongCovid #wastewater #prevention #COVIDisAirborne #COVID19 #CovidIsNotOver #longcovidkids

I think it's wild to remember how terrified we all were of AIDS back in the day, when HIV infection was so much easier to avoid. Covid comes along and... shrug.

#covid19 #CovidIsNotOver #covid #Tcells #ImmunityTheft #LongCovid #Mask #HIV #AIDS #CDC #WHO #pandemic #tripledemic

In April 2020, I observed some unusual activity involving people on Twitter who claimed to be doctors and appeared to be having an outsized influence not only on Twitter discourse related to COVID, but on actual COVID policies. I tweeted about it at the time and got shouted down by people saying I was being disrespectful to the “heroes” of the pandemic (I wasn’t). Well, that story is finally starting to unravel. As it turns out, some of those “doctors” weren’t actually doctors at all. 1/