Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
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New work from the lab out in Cell today, by En Yang and colleagues:
A brainstem integrator for self-location memory and positional homeostasis in zebrafish
"Cancer and aging are accompanied by stereotyped changes to the epigenetic landscape, including progressive loss of DNA methylation over gene-poor genomic regions (1, 2). Global hypomethylation arises in cells that have undergone many divisions, likely owing to imperfect maintenance. Evidence suggests that global hypomethylation represents a “mitotic clock” that counts divisions in somatic cells and functions to restrain aging cells and limit malignant progression."
Thiago Carvalho
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Algorithm Warfare: How Elon Musk uses Twitter to control brains. Mastodon is the only way https://georgelakoff.substack.com/p/algorithm-warfare-how-elon-musk-uses
Thiago Carvalho
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I forgot to post here that my article on #RNA as the molecule of the future was publish @DavidsonOnline in the begining of the month in Hebrew https://davidson.weizmann.ac.il/online/sciencepanorama/%D7%9E%D7%95%D7%9C%D7%A7%D7%95%D7%9C%D7%AA-%D7%94%D7%A2%D7%AA%D7%99%D7%93
It was now also published in Arabic
Thiago Carvalho
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#SocialMedia #Twitter #Musk #FreeSpeech: "In the middle of a workday, Sasha Solomon, a 34-year-old software engineer in Portland, Ore., put her French bulldog, Bosworth, on a leash and walked down a leafy street to a favorite coffee shop.
It seemed like an ordinary November afternoon, or as ordinary as it could be for someone working at Twitter under its mercurial new owner, Elon Musk. Ms. Solomon ordered a latte for herself and a drip coffee with cream for her husband. Then she and Bosworth headed back home.
Sitting at her computer on her living room couch, she tried to check the latest messages on Slack, only to find her account was locked. She then pulled up her work email account, or tried to. Also locked. She logged onto her personal email account and saw something in her inbox from a human resources executive at Twitter.
“Your recent behavior has violated company policy,” the email said, according to Ms. Solomon. She turned to her husband and said, as she recalled in a recent interview, “I guess I don’t work here anymore.”
With that, Ms. Solomon had become part of a small number of media industry employees who lost their jobs this year after using Twitter to take on the institutions where they worked. In Ms. Solomon’s case, she directly challenged her boss in a series of tweets. She said she is not sure whether those tweets caused her to lose her job, or if she was just one of the roughly 3,700 Twitter employees who got the ax in layoffs that began soon after Mr. Musk took ownership of the company in October."
https://www.nytimes.com/2022/12/23/style/twitter-elon-musk-sasha-solomon.html
Thiago Carvalho
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Look! @JoyceCarolOates has joined the Fediverse.
"To their Indigenous descendants, the stories we tell about these First Peoples of the Americas are highly relevant for additional reasons. Their deep ties and claims to the lands have often been ignored or expunged by governments, media and corporations across North and South America in order to make room for narratives that are more palatable, exciting or convenient to certain non-Native groups. The historical exclusion of Indigenous peoples from making decisions about research on their own ancestors and lands has caused significant harms to Native communities and individuals; when Native scientists and community members are full participants in the research process, the stories that emerge are not only more respectful but also more accurate."
https://aeon.co/essays/the-first-americans-a-story-of-wonderful-uncertain-science
'An alternative to gene therapy is enhancing the enzymatic activity through small molecules, an approach pursued by Bial, based in Portugal, which is conducting phase 2 trials of LTI-291, an activator of glucocerebrosidase acquired from Lysosomal Therapeutics.'
Thiago Carvalho
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For the holiday, a thread on how to befriend crows.
--
Befriending crows is a wonderful thing.
I have many crow friends at home and at work. They bring joy at unexpected moments and can rescue a miserable day even without shaking down the dust of snow that Robert Frost described.
This thread is an updated version of one I posted at the bird site in July 2019.
#birding #birdwatching #birds #urbanbirding #crows #corvids #crow #corvid #crowfriends
Thiago Carvalho
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Important thread from Dr. Gwen Randolph at WUSTL on her efforts to support women and fight misogyny from the inside: https://twitter.com/gwenrandolph_/status/1606270605149368320?s=12&t=PrXM8cP9ziV_QI8jht2CYg
Thiago Carvalho
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Henrietta Lacks is about to get recognition despite the fact that it comes after decades of silence. Her sacrifice wasn’t voluntary but the entire world owes her regardless.
#blackfriday #blackmastadon #blackjoy #science #medicine
https://www.theguardian.com/us-news/2022/dec/21/henrietta-lacks-statue-replaces-robert-e-lee-monument-virginia
Thiago Carvalho
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NEW: Elon Musk sent a Signal message ordering his staff to aid in the Twitter Files: "please give Bari [Weiss] full access to everything at Twitter. No limits at all.”
That triggered a frenzy inside Twitter, which was under a decade-old FTC order. IT staff refused to onboard Weiss, worried Twitter would be breaking the law.
Days later, two executives were fired.
"These guys did amazing damage,” a former employee told me of the Musk subordinates running the company.
https://www.washingtonpost.com/technology/2022/12/24/elon-musk-twitter-meltdown-tesla/
Thiago Carvalho
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RT @GwenRandolph_
Today is the opening day for the movie Women Talking. I cannot find a venue yet. Searches led me to this cancelled university screening for Dec 1. It is not hard to see “CANCELLED: Women Talking” as appropriate signage @WUSTL, for everything we have learned, seen here this month
Thiago Carvalho
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Our faculty of Maths & Computer Science at TU/e @TUEindhoven is recruiting 24 (!) new faculty - open rank. I would _love_ to welcome you as a new colleague! #hiring #tenuretrack #faculty #jobs #academicjobs #newpi https://www.tue.nl/en/working-at-tue/scientific-staff/ready-for-the-next-step-in-your-academic-career/?utm_source=linkedin&utm_medium=post&utm_campaign=teaser+broad+hire&utm_id=24+positions+M%26CS
Thiago Carvalho
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Postdoctoral Research Position in the Mi lab at Yale University @weimi11
Dr. Wei Mi's laboratory at Yale is looking for a postdoc with background in bacterial genetics, fluorescent microscopy, or structural biology.
https://jobrxiv.org/job/yale-university-27778-postdoctoral-research-position-in-the-mi-lab-at-yale-university/?feed_id=32766
#Scien...
https://jobrxiv.org/job/yale-university-27778-postdoctoral-research-position-in-the-mi-lab-at-yale-university/?feed_id=32766
Thiago Carvalho
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Last year, Jonathan Van-Tam gave 3 lectures on #covid that were available only in the UK. I pleaded with the Royal Institution to release them earlier, because they are top quality for younger students: how a virus enters a cell, PCR, exponential growth, the size of the human genome,...if you bundle up all of your B cells to form a ball: how big would that be? Even llamas make a guest appearance.
Terrific #scicomm, and everyone can enjoy them during this holiday season:
Thiago Carvalho
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#introduction Hi All. I am @tisimpson on Twitter, just starting on here.
I'm interested in the application of computational/statistical methods to biomedical areas. Much of our work involves using multi-modal data: #genomic, #clinical, and #molecular to better understand neurological disease of genetic origin.
We develop and use a lot of #network, #dataintegration, #statistics, and #machinelearning approaches in our research.
Thiago Carvalho
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"Twitter removed a feature in the past few days that promoted suicide prevention hotlines and other safety resources to users looking up certain content, according to two people familiar with the matter who said it was ordered by new owner Elon Musk"
Only a real asshole would do this. Ladies and gentlemen, Elon Musk. #Mastodon #News #Birdsite #SuicidePrevention
Thiago Carvalho
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#Twitter has privately demanded suspended journalists delete the tweets that drew Elon Musk’s ire in the first place — a condition the reporters have refused to accept. "The result is a stalemate: The suspended journalists remain in Twitter purgatory, unable to access their accounts." -- Paul Farhi in the Washington Post. https://wapo.st/3YO5KiQ
Thiago Carvalho
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1/2 Dr Peter Hotez warns: “The next big coronavirus pandemic is coming – the fourth one. I can’t tell you if it’s going to be next year or five years or 10 years, but it’s coming,” he warned.
“The reason why we’re seeing more and more of this is, in part, because of climate change and urbanization – human migrations encroaching into territories where bats are. It’s a combination of climate change with other social determinants.”
Hotez is co-director of the Center for Vaccine Development at Texas Children’s hospital and dean of the National School of Tropical Medicine at Baylor College of Medicine in the US
#Coronavirus #pandemicrisk #pandemic#zoonotic #climatechange #urbanization
https://www.theguardian.com/world/2022/dec/23/covid-cases-death-rate-risk-peter-hotez
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
